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Tag: "hemophilia" at biology news

Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers

...e treatment of liver-based genetic defects such as hemophilia A and B in humans. Mouse embryonic stem cells tre...and then injected into the liver reverse a form of hemophilia in mice analogous to hemophilia B in humans, the new study shows. A report of the study appears in t...

Redesigned protein accelerates blood clotting

Study holds hope for next generation hemophilia treatment Researchers have doubled the potency of ...sive bleeding in 30,000 Americans. In most cases, hemophilia is caused by a lack of factor VIII, one of several proteins that enable blood to solidify, or clot, ...

Gene therapy advance treats hemophilia in mouse models

...nt potential for developing improved treatment for hemophilia but are not yet applicable to people, cautioned Pa...hieve levels of gene expression that converted the hemophilia A in the mouse from a severe to a mild form. The correction lasted 30 weeks -- the duration of the s...

New results validating Pall prion reduction filter disclosed at ISBT Congress

...Society also issued a warning to 6,000 people with hemophilia that they could have caught the disease through infected blood. In the U.S., a second cow just tested positive for BSE. "Considering the lengthy, asymptomatic incubation period of vCJD in people, no one can accurately determine the magnitude of the ...

HIV inserts into human genome using a DNA-associated protein

...osomes, such as in the delivery of Factor VIII for hemophilia patients. HIV integrates into active transcription units on chromosomes within the nucleus of human cells. These units are sites that lead to efficient expression of the viral genome. Most HIV-infected cells in a patient will have a very short life...

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds

...chnique that has shown promise in skin disease and hemophilia might one day be useful for treating muscular dyst...ure for the disease and for other diseases such as hemophilia and the skin disease, epidermolysis bullosa. Early trials using her approach have looked promising i...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

... degree to which these patients have problems from hemophilia stems from how much of this protein, factor VIII, ... More than 18,000 Americans, nearly all men, have hemophilia A, the most common form of the disease, according to the Centers for Disease Control and Prevention....

Polymer aids in blood clotting, pointing way to new treatment

... sustained on battlefields or in accidents, or for hemophilia and other diseases with coagulation deficits. "The big picture is that we've found a new function for an ancient molecule," he said. "Polyphosphate has been around for billions of years. Roberto's discovery that the granules in platelets are like th...

A transplant in time

... a critical blood-clotting protein. Treatments for hemophilia and other such genetic diseases, when they exist, may consist of risky blood transfusions or expensive enzyme replacement therapy. But what if the body could be induced to begin producing these proteins, say by transplanting healthy tissue with the a...

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