Viral DNA sequence a possible trigger for breast cancer
...e in question is usually found in immune cells and helps trigger the activation and proliferation of the cells. These sequences have also been found in proteins from some other cancer-causing viruses such as Epstein Barr virus and Kaposi's sarcoma virus, but what role this sequence plays in cancer developm...Molecular biology fills gaps in knowledge of bat evolution
...n that is now North America. This latest research helps fill gaps in the evolutionary history of one of the most diverse group of mammals on earth and the only mammals capable of powered flight. The fossil record alone left bat evolutionary history about 61 percent incomplete, according to Springer. Bats ...Lack of enzyme turns fat cells into fat burners
...2 diabetes."This adds another tissue or organ that helps out in the process ofenergy maintenance," said Wakil. "ACC2 is potentially a key enzyme inthe regulation of weight, obesity, and related problems."Wakil and his colleagues studied the oxidation of fatty acid andglucose in cultures of fat cells isolat...Research advances quest for HIV-1 vaccine
...the critical features of 4E10 recognition of HIV-1 helps to define potential immunogens able to elicit 4E10-like antibodies. This is an excellent example of the tremendous potential for accelerating HIV vaccine design when scientists from multidisciplinary laboratories come together to tackle a major scien...U-M scientist to talk about tissue engineering at AAAS
...o badly to simply heal on its own. A tiny scaffold helps direct the engineered cells to the right place, then dissolves once the cells begin to generate to fill in the wound. "In certain kinds of defects, the body cannot heal itself and the body needs a jumpstart," Krebsbach said. To heal a large wound, l...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...is focused on afamily of genes known as P53, which helps to regulate the cell cycle.They have also moved their studies to a new model system: thezebrafish, a vertebrate with more similarities to humans.Reinisch's work on BCE is funded by a STAR grant from the United StatesEnvironmental Protection Agency. S...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...is focused on afamily of genes known as P53, which helps to regulate the cell cycle.They have also moved their studies to a new model system: thezebrafish, a vertebrate with more similarities to humans.Reinisch's work on BCE is funded by a STAR grant from the United StatesEnvironmental Protection Agency. S...New Clues Add 40,000 Years to Age of Human Species
... deposits and the Mediterranean sapropels not only helps us resolve an anthropological mystery, but it provides a whole new perspective on the history of the Turkana Basin, a setting that has provided so much important evidence regarding human evolution,?says Brown. “However, while our research pushes ...Enzyme shown to help protect genomic stability
...tential destabilizing molecular events. The enzyme helps to keep the genome structurally closed, unavailabl...d a molecular mechanism to explain how this enzyme helps keep telomeric DNA silenced and potentially protects the genome from destabilizing activity," says N...Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
...how one key player -- a protein called clathrin -- helps regulate endocytosis like a well-oiled machine. It may also give us insights into the kinds of disease states that can happen when clathrin-regulated endocytosis goes wrong. The findings, already published online, will appear in the April print edit...Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...e of a protein on the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec. 16 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atprotecting children against the disease. The St. Jude researchersdeterm...New comparative toxicogenomics database
...e of a protein on the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec. 16 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atprotecting children against the disease. The St. Jude researchersdeterm...Highly adaptable genome in gut bacterium key to intestinal health
...vive rapidly changing nutrient conditions but also helps maintain the functions and stability of the gut's ...ing behavior benefits the bacterium and presumably helps maintain the stability of the microbial society that it is an integral part of." The dietary switch...Gene Therapy For Parkinson's Disease Moves Forward In Animals
... by producing therapeutic levels of a protein that helps nourish brain cells, said Ron Mandel, Ph.D., a scientist with the University of Florida's McKnight Brain Institute and Genetics Institute who was part of the research team. The protein, called GDNF, short for glial cell line-derived neurotrophic fac...New RNA polymerase discovered in plants
...certain death in mice. Pikaard thinks that Pol IV helps make siRNAs that then direct DNA methylation to sequences matching the siRNAs. The results were published in Cell online, Feb. 10, 2005 and will appear in the March, 2005 print version of the journal. "Pol IV is somehow involved in maintaining the ...Gene therapy for Parkinson's disease moves forward in animals
... by producing therapeutic levels of a protein that helps nourish brain cells, said Ron Mandel, Ph.D., a scientist with the University of Florida's McKnight Brain Institute and Genetics Institute who was part of the research team. The protein, called GDNF, short for glial cell line-derived neurotrophic fac...International HapMap consortium expands mapping effort
... of one percent difference is important because it helps explain why one person may be more susceptible to a certain disease than another. For any given disease, such as type II diabetes or coronary artery disease, researchers can use the HapMap to compare the genetic variation patterns of a group of peopl...Antibiotic might fight HIV-induced neurological problems
...ion known as encephalitis. The other protein, p38, helps trigger a series of events that result in a cell's programmed death, called apoptosis. Only one of the five treated monkeys showed any signs of encephalitis, and that monkey's condition was deemed mild by a set of standard measures. After the same a...Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
...purs an immune response without live bacteria, LPS helps to reveal how the immune system works on its own, without the complication of side effects. The team found that E. coli-infected pups later injected with LPS had significantly lower concentrations of cytokines called interleukins than control pups (...... Pulsed-HIFU instead renders tissues permeable and helps target them for taking up genes and other therapeutic substances injected into the body. "Basically, we're using sound waves to open up the tissue by producing gaps between the cells, making it leakier and more prone to taking up various genes, agen...