Cracking open the black box of autoimmune disease
... is important for understanding how they control a healthy immune response. "Autoimmune diseases take a tremendous toll on human health, but on a strictly molecular level, autoimmunity is a black box," says Young. "When we discover the molecular mechanisms that drive these conditions, we can migrate from...Targeting tumors the natural way
...ively seek out and kill cancer cells while sparing healthy ones. The new tumor targeting strategy, presented...s strategy has the potential to kill cancerous and healthy cells indiscriminately. "This study suggests that the cell recognition mode we used can direct an ...MicroRNAs can be tumor suppressors
... a tumor suppressor to prevent cancer formation in healthy cells. ...Organic is healthier: Kiwis prove that green is good
...significantly increased levels of polyphenols, the healthy compounds found in red wine and coloured berries. They also had a higher overall antioxidant activity, as well as higher levels of ascorbic acid (vitamin C) and important minerals compared with their conventionally grown counterparts (Journal of the ...Morphine makes lasting -- and surprising -- change in the brain
...ween inhibitory neurons and dopamine neurons. In a healthy brain, inhibitory cells would limit the release of dopamine, the "pleasure chemical" that gets released by naturally rewarding experiences. Drugs of abuse, from alcohol to cocaine, also increase dopamine release. So the net effect of morphine and ...Brown team finds crucial protein role in deadly prion spread
... proteins that cause fatal brain diseases ?convert healthy protein into abnormal protein through an ultrafast process. This good-gone-bad conversion is one way that prions multiply and spread disease. But scientists believe that there is another crucial step in this propagation process ?fragmentation of e...Light-based probe 'sees' early cancers in first tests on human tissue
...fiber-optic device reliably differentiated between healthy and precancerous digestive tissue taken from the stomach and esophagus of three patients known to have a precancerous form of a condition called Barrett's esophagus. In less than a second, their fa/LCI-enhanced version of an endoscope, instruments us...Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients
...od vessels. The MSC cells are derived from normal, healthy adult volunteer bone marrow donors and are not derived from a fetus, embryo or animal. Because they are in an early stage of development, it is believed that they do not trigger an immune response when placed in someone else's body. Similar to Blo...Magic Beans -- Anti-obesity soya could help prevent diabetes
... Protein Association, said: "Soy fits in well to a healthy balanced diet which is important in preventing diabetes ?low in fat, high in fibre and a good source of complex carbohydrates." ...Colour sensor breath test can detect lung cancer
...ith different types of respiratory disease, and 21 healthy people. Included in the group with respiratory illness were 49 people with small cell lung cancer at various stages of development. The research team used the sensor results from 70% of the study participants to develop a predictive model, the ...Brain tissue reveals possible genetic trigger for schizophrenia
...A expression between people with schizophrenia and healthy people. Using bioinformatic analyses, we found that the distinguishing microRNAs appear to regulate genes involved in synaptic plasticity." Acknowledging this was a pilot study, Perkins and her colleagues plan further research with larger tissue s...Breathing easy: When it comes to oxygen, a bug's life is full of it
...s play in the ability of its nerve cells to remain healthy even under hypoxic conditions. The research aims to lead to better ways to protect humans who suffer periods of hypoxia due to medical emergency or accidents. Mark Krasnow, of the Stanford University School of Medicine, Palo Alto, California, will...Overfishing large sharks impacts entire marine ecosystem, shrinks shellfish supply
...impact on local communities that depend so much on healthy fisheries," says Charles Peterson, a professor of ...ations of top predators is critical for sustaining healthy oceanic ecosystems," says Peterson. "Despite the vastness of the oceans, its organisms are intercon...MIT bioengineer advances survival, promise of adult stem cells
...ed to an injury site and induced to grow into new, healthy tissue. The research appears in the January 18 online issue of Stem Cells. Griffith's team focused on the potential for mesenchymal stem cells to grow into new bone in patients with bone cancer or severe bone injuries. Current treatment for such p...Widely used hepatitis B drug spurs HIV drug resistance
...f entecavir with 100,000 human immune cells from a healthy blood donor, then infected them with an HIV test virus and measured the number of cells infected over time. The lab test, developed at Hopkins by study co-author Robert Siliciano, M.D., Ph.D., a professor at Hopkins and a Howard Hughes Medical I...Light wine intake is associated with longer life expectancy in men
..., getting enough physical activity and following a healthy diet and quit smoking, if you smoke. There is no scientific proof that drinking wine or any other alcoholic beverage can replace these conventional measures....Researchers show that veins stiffen as we age
...earch team recruited 24 people for their study--12 healthy young adults between the ages of 18 and 30, and 12 healthy older adults between 60 and 70 years old. Each individual underwent medical screening at Christiana ...Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal
... a better alternative to a donor heart ?their own, healthy heart," she added. Professor Sir Magdi Yacoub, from the Heart Science Centre at Imperial and the Royal Brompton and Harefield NHS Trust, said: "We are impressed by the dramatic, sustained improvement in the condition of these severely ill patien...Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese
... fat diets. In contrast, the HCR group had normal, healthy livers. Links to Calorie Restriction Lifespan Model The researchers also looked for metabolic ties to resveratrol's impact: pathway changes that mimicked those caused by calorie restriction. They examined AMP-activated kinase (AMPK), a metabol......ng was equivalent to that accrued over 11 years in healthy people (178 base pairs). Telomere length was also significantly associated with the severity of osteoarthritis. The more severe the disease, the shorter was the telomere length. The authors suggest that both the ageing process and osteoarthritis ...