Bacteria collection sheds light on urinary tract infections
...rug-resistant bacteria could have an animal origin has major public health implications because of the pr...ording to DebRoy. The Gastroenteric Disease Center has been collecting E.coli samples since 1965 and is the largest repository of E.coli in North America. ...Bound for destruction: Ubiquitination protects against improper Notch signaling
...tant molecular signaling mechanism whose existence has beenknown, or at least hinted at, for nearly a century since theidentification of a mutant strain of Drosophila fruit flies with“notched?wings in Thomas Hunt Morgan’s lab in 1910. Later studiesrevealed that the Notch gene encodes a receptor protein t...Imaging Lymph Nodes with Nanoparticles
...t of this workup is assessing whether or not there has been lymphatic spread. Currentmethods include surgical removal of nodes for examination and varioustypes of imaging, ranging from ultrasound to newer technologies such asmagnetic resonance imaging (MRI). All these methods have problems; someare very ...U-M scientist to talk about tissue engineering at AAAS
...e graft from someplace like the hip. That approach has problems both for the wound at the donor site and ...ll not heal on their own, Krebsbach said, and that has led to research in biomaterials, bone and connective tissue function, and then tissue engineering. ...Finding Cures For Tropical Diseases: Is Open Source An Answer?
...addition to the"non-profitable" one. PLoS Medecine has an article about a possiblesolution titled "Finding Cures for Tropical Diseases: Is Open Source an Answer?" The whole article is a very good read; a summary from ScienceDaily is available in the full post. Onlyabout 1% of newly developed drugs ...Genome-wide mouse study yields link to human leukemia
...ww.nature.com/ng/. "This is the first time anyone has examined methylation in leukemia on a genome-wide basis in a mouse, and the findings offer important implications for patient care, since we know that methylation, which alters gene function, can be reversed," says Christoph Plass, senior co-author a...Breakthrough Microarray-based Technology for the Study of Cancer
...een announced by Agilent Technologies. The company has reported aninnovative method that enables the rapi...e NationalHuman Genome Research Institute, Agilent has developed a specialisedmicroarray platform that uses total genomic DNA to overcome severalscientific...The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
...Biology Laboratory (EMBL), announced today that it has signed a licensing deal with technological leader ...e group at EMBL developed SPIM. "Molecular biology has graduated upwards from studying single molecules - now we need to watch complex, three-dimensional p...Learning to fight an adversary that won't stay down
...iscovery over the past six or seven years and this has failed miserably." The scientist, whose work is s...y Science and Engineering Research Canada (NSERC), has organized a symposium on the evolutionary genetics of antibiotic resistance at the 2005 meeting of t...Scientists find missing enzyme for tuberculosis iron scavenging pathway
...of multi-drug resistant strains of M. tuberculosis has prompted the search for new drug targets and a better understanding of the mechanism of resistance in this bacterium. Several spans of DNA in the M. tuberculosis genome have been annotated as antibiotic resistance genes due to their sequence similar...Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6
...Linker products is the front-line investigator who has data andneeds a powerful, intuitive tool to analyze it....Found: Missing sequence of the human Y chromosome
... tumors associated with theundifferentiated gonad, has been genetically mapped to the region.Because the "missing" sequence described in this study contained eightputatively active genes, further functional testing of these genes mayreveal insights into the genetic basis for stature and gonadoblastoma....U of M researcher examines newly emerging deadly disease
...h due to hypertension and shock. Purpura fulminans has been identified in five cases in the Minneapolis-S... of Clinical Infectious Diseases. This new disease has also been determined in seven additional cases nationwide. Of the 12 known cases, only two patients ...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
...outhern California. Recently, the West Nile virus has been responsible for a viral encephalitis outbreak in the northeast. The NYU researchers set out to determine how the body can fight viral encephalitis. Specifically, they examined how type I interferons--proteins made by the body that are released i...Study finds more than one-third of human genome regulated by RNA
...of the most recentgenome-sequencing data, the team has compared human genome data withthat of the dog, chicken, mouse, and rat. For each of the microRNAs andprotein-coding genes that are common to these five species, the teamlooked for correspondence between the microRNAs and the protein-codinggenes. The...Marburg virus disease in Angola - update
As of 29 March 2005, the Ministry of Health has reported a total of 124 cases and 117 deaths in Cabinda, Luanda and Uige. All these cases had originated in Uige Province. Ten of these cases have been laboratory confirmed by the Centers for Disease Control and Prevention (CDC), Atlanta, USA. The t...Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
... involving the implantation of a retina mircrochip has allowed Emory Eye Center and the Atlanta Veterans Affairs Rehabilitation Research & Development Center to implant the device in several patients. The patients all have retinitis pigmentosa with moderate-to-severe vision loss. Three centers in the......says Steve Palumbi of Stanford University. Palumbi has applied new genetic techniques to penetrate over a...n. Piecing together their ancient family trees, he has discovered that the Antarctic population of minke whales is now the longest surviving whale populati...NYU researchers simulate molecular biological clock
...of the most recentgenome-sequencing data, the team has compared human genome data withthat of the dog, chicken, mouse, and rat. For each of the microRNAs andprotein-coding genes that are common to these five species, the teamlooked for correspondence between the microRNAs and the protein-codinggenes. The...... circumstances of a crime scene or the environment has caused DNA samples to become degraded. "We hope th...rk anytime soon. But we do think this breakthrough has many applications yet to be discovered and we look forward to working with our colleagues to thoroug...