International trial of two microbicides begins
...date topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsor...y Indevus Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in both laboratory and animal testing. It is believed to a...Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease
...nry Dreyfus Foundation and by Duke University. It has been difficult to study the chemistry of formation of these fibrils within the brains of humans and other animals, said Akhremitchev, who is an assistant professor of chemistry. In the brain, "monomers of all kinds are suspended in a soup in equilib...MetaChip provides quick, efficient toxicity screening of potential drugs
...date topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsor...y Indevus Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in both laboratory and animal testing. It is believed to a...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...ilable to researchers nationwide. Duke University has filed a patent application for cysmethynil, Casey ...e small molecule inhibitor of Icmt, a protein that has been shown to be an important player in keeping a cancer-causing gene called 'Ras' turned on inside ...Simple drug has the potential to save many lives threatened by malaria
...en with severe malaria before they reach hospital, has the potential to save many lives, say researchers ...timalarial treatment close to home to reduce delay has the potential to save many lives, they conclude. http://press.psprings.co.uk/bmj/february/ppr334.p...Tiny scaffolding allows stem cells to become working fat cells
...ronment in which a community of cells finds itself has a great deal of influence on the biology underway ...ng and obesity, a person's population of fat cells has other vital roles. Fat cells extract lipids, or fatty acids, from the bloodstream. They also become...Plants defy Mendel's inheritance laws, may prompt textbook changes
Contrary to inheritance laws the scientific world has accepted for more than 100 years, some plants reve...ster. "If you take this mutant Arabidopsis, which has two copies of the altered gene, let it seed and then plant the seeds, 90 percent of the offspring wi...UCSD discovery may help extend life of natural pesticide
...logists at the University of California, San Diego has discovered a molecule in roundworms that makes them susceptible to Bacillus thuringiensis toxin, or Bt toxin--a pesticide produced by bacteria and widely used by organic farmers and in genetically engineered crops to ward off insect pests. Their fin...The very unexpected life and death of a leukemic cell
.... The progression of the disease is slow and there has been a lack of information regarding the rate of p... Heavy water is made using a form of hydrogen that has twice its normal mass, making the water molecule "heavier" than normal. The special hydrogen serves ...White blood cell waste disposal system plays critical regulatory role
...lecule called IL-23 that is produced by phagocytes has been shown to stimulate IL-17 production. Dr. Klaus Ley and colleagues from the University of Virginia investigated whether ingestion of apoptotic neutrophils influenced IL-23 production by phagocytes. The researchers observed that the amount of IL-...New RNA polymerase discovered in plants
...rsity professor of biology in Arts & Sciences, has discovered a fourth kind of RNA polymerase found o...re different for Pol IV." Pikaard said the Pol IV has a perfect match in rice, the only other plant genome to be sequenced, despite rice being a monocotyl...Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
...the initiation and progression of these tumors. It has been established that interfering with the functio... one gene, called Adenomatous Polyposis Coli (APC) has a profound effect on the cells lining the innermost layer of the colon (called the epithelium) and c...NJIT Presidential Award winner takes stem cell research another step
...icine and Dentistry of New Jersey, Newark. Arinzeh has received a $100,000 grant from the Musculoskeletal...drive to advance the science of stem cell research has gained her national recognition. In the fall, she earned the highest honor given to a young research...Bird Brains Show How Trial and Error May Contribute to Learning
...m HHMI. "It makes sense that one part of the brain has as part of its job introducing that kind of variability." Kao began with an experiment to stimulate the region of the forebrain called LMAN (lateral magnocellular nucleus of the anterior nidopallium). In the avian brain, LMAN receives input about co...Agilent Technologies releases automated literature search tool for biology researchers
... to facilitate our own research collaborations and has proved very successful for us. We are excited to provide this to researchers everywhere so that they can analyze their own data more effectively and put it into a biological context." With the Agilent Literature Search tool, researchers enter the na...New methods of gene delivery using lasers
...in biomedicine and healthcare. Optical technology has huge potential for novel developments in the bio-medical field and St Andrews has outstanding research groups in this area. The new method -which involves a miniature violet laser -i......stitute of Bioengineering and Nanotechnology (IBN) has developed a novel method to simultaneously control...nal, Angewandte Chemie, and a United States patent has been filed on the invention. Research Scientist Dr. Yu Han and IBN Executive Director Prof. Jackie ...Influenza vaccine uses insect cells to speed development
...to produce the hemagglutinin. The FluBlok vaccine has recently finished phase II clinical trials, where it has established safety and the ability to elicit a strong antibody response in humans. "Since all the m...Boosting HIV screening can increase survival and is cost effective
...antial morbidity and mortality," said Paltiel. "It has a long asymptomatic phase, which can be diagnosed using very effective, inexpensive tests. Most importantly, early detection speeds linkage to proven, life-prolonging care and effective counseling to prevent further transmission." Rochelle Walensky,......f organisms. The rapidly growing body of knowledge has created the need for researchers to develop a shar... scientists, known as the RNA Ontology Consortium, has now been formed to do just that. "The consortium will develop a common vocabulary and scientific co...