Changing length of days reverses how estrogen affects aggressiveness in mice
...ort days (limited daylight as in winter), the drug halting estrogen production made the normally aggressive mice less aggressive. In mice kept in long day length conditions (as in summer), the normally docile mice were more aggressive. This showed that estrogen was indeed controlling levels of aggression in ...Hope for a more effective and less toxic cancer drug
...ding cancer cells. This is sometimes successful in halting the disease, but these drugs inevitably damage many normal tissues. Hence, even when the chemotherapy works, the side effects for the patient can be very serious. ABT-737 is a drug with a different strategy for attacking cancer. Rather than attem...Plant-derived molecules, genetic manipulation point to future chemoprevention methods
...pounds inhibited inflammation in a number of ways: halting nitric oxide production, blocking cyclooxygenase and nitric oxide expression, curbing proliferation and inducing apoptosis in human lung cancer cells. They tested CDDO-MA and LG100268 on mice for 20 weeks. CDDO-MA and 268 reduced the number of lun...MIT material stops bleeding in seconds
...sed to achieve complete hemostasis, the process of halting bleeding from a damaged blood vessel. Doctors currently have few effective methods to stop bleeding without causing other damage. More than 57 million Americans undergo nonelective surgery each year, and as much as 50 percent of surgical time is sp...Key to zebrafish heart regeneration uncovered
...how poor invasion of the newly regenerating cells, halting the formation of new heart muscle." Poss said that a continued understanding of the processes involved in regeneration of the zebrafish heart could lead to therapies to repair human heart muscle damaged by disease or heart attack. "Multiple typ...New research shows why too much memory may be a bad thing
...ecision making. "We were surprised to find that halting neurogenesis caused an improvement of working memory, which suggests that too much memory is not always a good thing, and that forgetting is important for normal cognition and behavior," said Gaƫl Malleret, Ph.D., a research scientist at the Center f...Destructive enzyme shows a benevolent side
...s pulled and the enzyme destroys the mRNA, quickly halting production of that protein. This new study found, however, that under stress conditions, the same enzyme ?while attached to the mRNA ?helps form temporary shelters within the cell called stress granules. There, the mRNA can be protected so that pr...A genetic 'gang of 4' drives spread of breast cancer
...ll four together had a far more dramatic effect on halting cancer growth and metastasis. Metastasis occurs when cells from a primary tumor break off and invade another organ. It is the deadliest transformation that a cancer can undergo, and therefore researchers have been looking for specific genes that prop......chestrates the expression of genes responsible for halting the uncontrolled growth of cancer cells. Although the study of the exact molecular mechanism is in its early stages, the researchers believe the separate chemical components work together to bolster the cancer-fighting power of butyrate. The doub...