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Tag: "halted" at biology news

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...hers." If compounds could be found that slowed or halted cancer spread, doctors could gain valuable time in shrinking the primary tumor. "If we had the luxury of time, we could treat that primary tumor at lower doses, too, with fewer side effects for the patient," Dr. Huang said. Until now, agents that sp...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...technology company, conducted the trials and later halted use of the drug because of safety concerns, creating an outcry from hopeful Parkinson's patients. But the gene therapy used in monkeys represents a different way to deliver the GDNF to the brain, causing the body to produce it naturally. It also pro...

Gene therapy for Parkinson's disease moves forward in animals

...technology company, conducted the trials and later halted use of the drug because of safety concerns, creating an outcry from hopeful Parkinson's patients. But the gene therapy used in monkeys represents a different way to deliver the GDNF to the brain, causing the body to produce it naturally. It also pro...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...ientists also show that E. coli evolution could be halted in its tracks by subjecting the bacteria to compou...ocking LexA in rodent models of E. coli infections halted the growth of antibiotic resistance. Three days after being subjected to antibiotics, the rodents sh...

Elusive salamanders have role in developing new sampling models

...e of a 100-year drought event that dried ponds and halted reproduction from 1999 through 2002. Since the first salamander was found six weeks ago, 36 more have been found in one pond, but none in 11 others that have supported them in the past. In the United States, flatwoods salamanders are found only in F...

New study finds how cells with damaged DNA alert the immune system

...hen genetic abnormalities occur, the cell cycle is halted so that the cell has time to fix the damage before the DNA is replicated. If the damage is too severe for the cell to repair on its own, it can trigger cell death, a process known as apoptosis. "All of this is happening autonomously within the cell,...

Renewed hope for Parkinson's patients

...hen genetic abnormalities occur, the cell cycle is halted so that the cell has time to fix the damage before the DNA is replicated. If the damage is too severe for the cell to repair on its own, it can trigger cell death, a process known as apoptosis. "All of this is happening autonomously within the cell,...

Chernobyl: The true scale of the accident

...tares taken from production. Timber production was halted in 694,200 hectares of forest. Remediation made "clean food" production possible in many areas but led to higher costs in the form of fertilizers, additives and special cultivation processes. Even where farming is safe, the stigma associated with Che...

Kenya halts first field trials of GM maize

...aize growing in open field trials. The government halted the research and ordered the destruction after discovering that a technician had sprayed a restricted pesticide on maize modified to resist attack by insects called stem borers. Wilson Songa, Kenya's agriculture secretary and chair of the National B...

DNA gene vaccine protects against harmful protein of Alzheimer's disease

...ed into muscle, Dr. Rosenberg said. That study was halted when a small percentage of participants developed inflammation of the brain and spinal cord. Injecting the gene, in contrast, caused no brain inflammation in the mice. Dr. Rosenberg said the difference was partly because in the human trial, the pro...

International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy

...DSMB recommended that enrollment into the trial be halted in light of the findings to date, and the SMART Executive Committee and NIAID agreed with the recommendation. Upon reviewing the results, the Executive Committee also conveyed to local study investigators its recommendation that it would be prudent t...

Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure

...to terminate this wave." The pulses successfully halted the wave 80 percent of the time, they reported. In the remaining cases, however, the pulses converted the single wave into multiple waves that continued to activate the cardiac cells at an accelerated rate. "In other words, instead of terminating it...

Anti-inflammatory drug's potentially deadly side effect found to be rare

...a serious brain infection in large clinical trials halted in early 2005. The new study found no new cases o...ral nervous system. Prior to the studies that were halted last year, earlier studies showed a 66 percent reduction in the rate of relapses in MS patients trea...

Jumping gene could provide non-viral alternative for gene therapy

...cy comes at a price. Gene therapy trials have been halted because of major complications, including deaths. As examples, one patient died because of his immune response to an adenovirus and three children in another study developed leukemia because the virus inserted itself upstream of a cancer-causing gene...

Mayo Clinic collaboration mining of ancient herbal text leads to potential new anti-bacterial drug

..., because that illness or affliction should not be halted too quickly; and some considered this medicament a great secret, and relied on it completely."...

Buildup of damaged DNA in cells drives aging

...DNA damage somehow triggered hormonal changes that halted growth, while also boosting maintenance and repair. Because growth hormone levels go down as we get older, contributing to loss of muscle mass and bone density, the investigators systematically compared the gene expression pattern of their progero...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

...attack islets and found that the protocol not only halted the immune destruction caused by diabetes but also allowed the insulin-producing pancreatic islet cells to regenerate. Evidence indicated that the spleen cells were the source of at least some of the regenerated islet cell and hastened the restoratio...

Male circumcision reduces HIV risk, study stopped early

... board's review, the National Institutes of Health halted the trial and recommended that all men enrolled in the study who remain uncircumcised be offered circumcision. "Circumcision is now a proven, effective prevention strategy to reduce HIV infections in men," said Robert Bailey, professor of epidemio...

British cattle give TB to badgers, finds UC Davis expert

...c of foot-and-mouth disease in England temporarily halted routine TB testing of cattle, infection rates in badgers doubled. At this time, infected cattle remained in their herds and the researchers suggest that this allowed them to transmit the disease to other cattle and to badgers. "Our findings helps to...

New research shows why too much memory may be a bad thing

...e, showed that mice in which neurogenesis had been halted made more correct choices and found the food faster. "In our world, we are constantly bombarded by new information so we are constantly filtering –and if we did not do this, we would be overwhelmed," said Dr. Malleret. "Our research indicates tha...

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