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Tag: "halt" at biology news

Study fishes out new role for prostaglandins

...Solnica-Krezel, "and sometimes one train wreck can halt the entire process." While 'bad timing' during development can spell the end for an embryo, finding ways to exploit this pathway could have beneficial effects in cancer cells. "The pathways important for regulating development are also dysregulat...

Neurons grown from embryonic stem cells restore function in paralyzed rats

..." Previous studies have shown that stem cells can halt spinal motor neuron degeneration and restore function in animals with spinal cord injury or ALS. However, this study is the first to show that transplanted neurons can form functional connections with the adult mammalian nervous system, the researche...

Possible birthplace of malignant brain tumors identified

...ed that the PDGF infusion caused the stem cells to halt their normal production of mature brain cells and launch into the abnormal proliferation pathway. Importantly, the researchers found that stopping the PDGF infusion caused a complete regression of the nodules. The researchers wrote that "these find...

Novel therapy combinations gain ground in treating hepatitis

...ighest dose (800 mg), forcing the research team to halt the use of that dose and continue using only the lower doses of 200 to 400 mg of the drug. "For patients whose disease has not responded to current therapies, this new combination treatment may produce excellent results, at the maximally acceptable ...

Researchers appeal for new regulations to save coral reefs from live fish trade

...ambridge, have called for action by governments to halt the unsustainable plunder of the world's ocean resources. For decades tropical coral reefs have battled for survival against a complex array of threats including pollution, coral bleaching triggered by rising sea temperatures and over-fishing. ...

New treatment for food poisoning

...atory. These tests measure whether antibiotics can halt the growth of Listeria in laboratory conditions. Such tests are usually a measure of how effective the drug will be in the body. When tested this way, Listeria had been shown to be resistant to the antibiotic, fosfomycin. As a consequence, this drug...

Dopamine drug leads to new neurons and recovery of function in rat model of Parkinson's

...h time. There are no treatments proven to slow or halt the course of PD. However, many researchers have been trying to find ways of replacing the lost neurons. One possible way to do this would be to transplant new neurons that are grown from embryonic stem cells or neural progenitor cells. However, ...

New angiogenesis finding may help fight cancer growth

... vessels, or angiogenesis. The finding may help halt tumor growth in cancer patients, says Emery Bresni... blocking angiogenesis could be a promising way to halt tumor growth. Also in June, the FDA approved a compound that inhibits VEGF for treating colon cancer...

UGA scientists engineer root-knot nematode resistance

.... Hussey and his research team have found a way to halt the damage caused by one of the world's most destructive groups of plant pathogens. Root-knot nematodes are the most economically important group of plant-parasitic nematodes worldwide, said Hussey, a distinguished research professor in plant pathol...

Mayo Clinic collaboration mining of ancient herbal text leads to potential new anti-bacterial drug

... Writes Rumphius: "... these same kernels ... will halt all kinds of diarrhea, but very suddenly, forcefully and powerfully, so that one should use them with care in dysentery cases, because that illness or affliction should not be halted too quickly; and some considered this medicament a great secret, an...

UGA scientists unravel 'molecular inch-worm' structure of walking-pneumonia bacterium

...ing a way to stop such attachment or gliding could halt infections or make them far less severe. "M. pneumoniae accounts for 20 percent of community-acquired pneumonias in this country," said Krause. "Finding out more about how the bacterium that causes the disease works gives us a new edge in thinking...

Insulin receptor stops progression of Alzheimer's disease

... that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School. Researchers have found that per...

Cancer stem cells linked to radiation resistance

...the drug in conjunction with radiation appeared to halt the resistance of cancer stem cells to radiation. This finding, the researchers said, suggests that use of a checkpoint inhibitor during radiation ruins the cells' potential to repair themselves and increases the likelihood that the cells will die. ...

Common cold virus leads to death in lung transplant patients

...ents, with impaired immune systems due to drugs to halt rejection, are at potentially higher risk from the virus. "Our evidence demonstrates that rhinoviral disease is not exclusively limited to the upper respiratory tract," said Dr. Kaiser. "It can also lead to lower respiratory complications, which i...

'Trojan Horse' agent halts bone metastasis in mice

...h this study tested the ability of VEGF121/rGel to halt the growth of human prostate cancer cells in the bones of mice, investigators say it likely could help prevent the growth of other cancers in bones such as breast, multiple myeloma, lung and renal cell. "Many tumors invade bone in the same way, so...

Distinguishing friend from foe in the battle against cancer

...nical trials has been combined with other drugs to halt cancer cell growth. But to cancer cells, rapamycin is both friend and foe. "Rapamycin is not as successful as initially expected in treating cancer," explains Ghosh. "Instead of killing cells, you end up triggering a survival response in them." Thi...

Key to lung cancer chemo resistance revealed

...d enzymes that sweep the cell clear of toxins. To halt the detox process, proteins manufactured by KEAP1 bind to the NRF2 triggers tagging them for destruction. In cancer cells, NRF2 activity runs amok, sweeping away all cellular toxins, including chemotherapy agents. Biswal says that blocking NRF2 a...

New study aims to stop sepsis in its tracks

...dy to determine whether specific interventions can halt the progression to severe sepsis and septic shock. Key to the project is determining whether there are "golden hours" during which prompt, rigorous, standardized care can save patients' lives. The project may establish the first set of standard pro...

Prion disease treatable if caught early

... intervention in human prion disease will not only halt clinical progression but allow reversal of early behavioral and cognitive abnormalities," wrote the scientists....

How T lymphocytes attack

...ey have previously learnt to recognise. They then halt to eliminate it, before resuming their rounds. The rapidity of the advance achieved by T lymphocytes is indicative of either the absence of an adversary, or defeat of the immune system in the battlefield. This scenario was published in The Journa...

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