RNA project to create language for scientists worldwide
...iginally believed. For instance, while genomicists had previously determined that humans and chimpanzees share 99 percent of the same protein genes, it has now been discovered in the past two years that so do mice. "The hardware (proteins) for mice and humans is practically the same–but clearly mice and...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...veld said. "In fact, all TEL2/MYC B-cell lymphomas had lost their p53 function." Grosveld's team found that this sequence of events modeled in the mouse also occurs in human lymphoma patients. Combined elevated TEL2 and MYC expression occurred in the B lymphocytes of over a third of patients with a B ly...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...ting ones. Pharmaceutical companies have also not had the luxury of protein-interaction databases. They have routinely identified promising new drugs based on trial-and-error screenings of those molecules' ability to completely disable target proteins. Ideker said protein interaction information could h...South America's vast pantanal wetland may become next everglades, UNU experts warn
... "Prior to the 1970s, the traditional stakeholders had limited impact on the resources they used and did not have the means to induce major environmental changes, such as altering the flood pulse by building dams or changing water quality by increasing the sediment load in rivers." "As economic developm...Falling ants glide back to trunk to avoid dangers of forest floor
...ee cavities and also collects adult females who've had a recent meal of blood ?his own. He and Dudley are applying for grants to do a more systematic survey to see how common gliding is among the hundreds of species of canopy ants as well as other insects that live in the trees, and to explore the biome...Unexpressed But Indispensable -- The DNA Sequences That Control Development
...day two of development, 23 out of 25 CNEs injected had upregulated GFP expression, indicating interaction of these sequences with endogenous transcription factors. Different CNEs caused different regional patterns of expression, in keeping with their presumed roles in distinct developmental processes. T...Scientists discover that host cell lipids facilitate bacterial movement
...oles these lipids play in Listeria infection. "We had expected to see PIP2 and PIP3 only at the very back of Listeria where new actin assembly was taking place," recalls Dr. Southwick. "To our surprise these lipids also localized to the front of the moving bacteria." The researchers also noticed that Li...UF Researchers Map Bacterial Proteins That Cause Tooth Loss
... specific functions.?/p> Until now, scientists had identified less than 2 percent of the pathogen’s proteins and had to guess at what other proteins might be present in the proteome based on similarities to other know...UCSD team discovers specialized, rare heart stem cells in newborns
...ardiac muscle cells formed were totally mature and had the complete array of function that one would expect in completely differentiated heart tissue," said the study's co-first author Jason Lam, Ph.D. candidate in the IMM. The cells exhibited contractility, pumping ability, the correct electrical physio...Key Trigger Of Opioid Withdrawal Symptoms Found
...biochemical studies on brain slices from mice that had been treated with morphine. Their objective was to understand what happens to a particular region of the midbrain--called the periaqueductal gray (PAG)--known to be involved in such withdrawal symptoms. Opiate addiction inhibits neuron activity in th...... rendered irresistible after the synthetic perfume had been applied. Smell is important when choosing a ..., when the perfume was added to males that already had the ideal range of MHC molecules, females could also be fooled into believing that these males smell...New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
...homa ?a cancer generally considered incurable ?who had not been previously treated with any other form of... percent responded to the treatment and 75 percent had a complete response, meaning no evidence of cancer remained. More than three-quarters of patients wi...Family trees of ancient bacteria reveal evolutionary moves
...Earth. This was a time when the Earth's atmosphere had an incredible, mysterious and inexplicable rise in...V light would have killed most things. They either had to have come up with ways to deal with the UV light ?and there is evidence that they made UV-absorbi...Gene therapy for Parkinson's disease moves forward in animals
... an approach against Parkinson's disease has truly had some ups and downs," said J. William Langston, M.D...riata. Before receiving the treatment, all animals had limited use in their left paws. After treatment, the animals receiving the therapeutic enzyme mixtur...VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
...etermined whether genes with changes in expression had a functional relationship with each other. For example, they determined that many genes regulated by alcohol participated in certain biological pathways, such as the one leading to the production of myelin. Myelin is a form of molecular insulation th...How an AIDS-Related Cancer Unleashes Inflammation
...o homology to any known gene," said Ganem. "So, we had no clue as to what the protein did. Since it was a very simple protein, we believed that it had no enzymatic function itself, but acted by binding to or activating other proteins," he said. Thus,...PCRM develops world's first cruelty-free insulin assay
...n diet on patients with type 2 diabetes. "We only had two options available to us when we began our diabetes trials," said Dr. Barnard. "One, we could use test kits with insulin antibodies grown in vivo--literally from cells injected into the abdomens of live mice--or we could use kits containing antibo...Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss
...than the thickness of a human hair. Four patients had surgery Tuesday, January 25. The fifth patient is scheduled for a later date. Rush principal investigator Dr. John Pollack performed the surgeries with Dr. Kirk Packo, Dr. Pauline Merrill, Dr. Mathew MacCumber, and Dr. Jack Cohen. All are members of...Sexual cooperation: Mating increases longevity in ant queens
...ve of whether males could transfer viable sperm or had been sterilized prior to mating. It remains unknown how mating increases the longevity of the females. Sexual cooperation, rather than sexual conflict, is promoted by the life history of social insects; whereas most insect females undergo repeated p......ve relationship with Isis Pharmaceuticals, we have had access to the very highest standard of technical and analytical resources to ensure that NittoPhase?will deliver unmatched performance.?/p> “Our internal testing and analysis of NittoPhase?has clearly validated this product in terms of technical ...