Scientists identify genetic pathways essential to RNA interference
...hose genes were essential to the RNAi process that had been suppressing expression of the fluorescence gene. Some of the identified genes ?many of which have human counterparts ?code for proteins involved with the packaging and processing of RNA, but others may be involved with the regulation of DNA its...Same mutation aided evolution in many fish species, Stanford study finds
...ion in a large number of marine fish, all of which had a complete set of armor plates. A small number of these fish had one copy of the Eda gene that contained the mutation in question. It's likely that when a pocket of...Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
...ich the foxes were driving toward extinction, Byrd had noticed the differences between islands with and w... speculated that nutrients might play a role. "He had these interesting ideas about foxes and birds and nutrient chains, and I thought we should do some s...Gene Therapy For Parkinson's Disease Moves Forward In Animals
... an approach against Parkinson's disease has truly had some ups and downs,?said J. William Langston, M.D....riata. Before receiving the treatment, all animals had limited use in their left paws. After treatment, the animals receiving the therapeutic enzyme mixtur...Researchers trace evolution to relatively simple genetic changes
...d, so much so that in the 19th century naturalists had counted about 50 different species. But since then...g because many of the men were missing their hair, had very few teeth, and couldn't sweat in hot weather. It's a very unusual constellation of symptoms, an...Scientists reveal molecular secrets of the malaria parasite
...project isAssociate Investigator Jane Carlton, who had led the sequencing of P.yoelii. At TIGR, Carlton constructed a composite of all three rodentgenome sequences (P. yoelii, P. berghei, P. chabaudi) by aligning themagainst the P. falciparum genome to create a whole-genome synteny mapof the four species...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...d, so much so that in the 19th century naturalists had counted about 50 different species. But since then...g because many of the men were missing their hair, had very few teeth, and couldn't sweat in hot weather. It's a very unusual constellation of symptoms, an...Studies reveal methods viruses use to sidestep immune system
...ted why cells with functioning RIG-I protein still had persistent HCV infection. In a study to appear in PNAS, Dr. Gale and his group found an explanation for HCV's tenaciousness. Once HCV infects the cell, it launches a counterattack against RIG-I, producing a protein called a protease to disrupt the ce...Development of portable infectious disease detector
...siderably moredifficult than most of the inventors had expected and the products thatthese companies have created thus far have been too expensive for thepoint-of-care diagnostics market.For their home fertility tester, Pria kept costs down by keeping theirsystem as simple as possible. Instead of trying ...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
...moth being studied, was filled first with air that had been freed of carbon dioxide. Next, a device measured when and how much carbon dioxide originated from the insect. Bradley explained that insects typically maintain 4-5 kilopascals of oxygen in their respiratory systems, 4-5 times lower than the nor...Scientists discover unique microbe in California's largest lake
...d switched places with the portionof the gene that had originally been inherited from the cyanobacterialp...utionary innovation bygenetic exchange has in fact had consequences for ribosome function inthese bacteria.The new species of Acaryochloris is the latest i...Potential Cure for Lymphoma in HIV patients
...ncer Center studied 20 patients(aged 11 to 68) who had HIV and lymphoma, either Hodgkin’s ornon-Hodgkin’s. The selected patients had undergone previousstandard-dose frontline chemotherapy for their lymphoma, but themajority either fa...Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...Then hormone treatment was stopped and the animals had lower growth hormone and IGF-1 levels the rest of their lives. That had an effect on cancer: 88 percent of "normal" male rats have tumors at death. The male rats that had a...New SARS Protein Linked To Important Cell Doorway
... that the organisms never use, and the researchers had no proof yet that SARS actually made use of the sequence their analysis identified. Geneticists call such sequences of genetic information open reading frames, and the SARS sequence therefore came to be known as open reading frame 7a, or orf7a. To p...NYC's First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention
...According to City health officials, the man -- who had previously had five negative HIV tests done by his private physician between September 2000 and May 2003 -- had unp...Jumping gene helps explain immune system's abilities
... similar tothe excision of jumping genes, but none had matched one of itscharacteristic oddities: As the unwanted DNA is being removed, theremaining DNA forms a tiny loop.Unexpectedly, when Hermes is being cut out of the DNA, the leftover DNAalso forms a hairpin loop, temporarily doubling back on itself,...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
... similar tothe excision of jumping genes, but none had matched one of itscharacteristic oddities: As the unwanted DNA is being removed, theremaining DNA forms a tiny loop.Unexpectedly, when Hermes is being cut out of the DNA, the leftover DNAalso forms a hairpin loop, temporarily doubling back on itself,...Scientists document complex genomic events leading to the birth of new genes
...squito, and pufferfish) for single-copy genes that had evolved more than one copy in humans. "Gene duplic...colleagues was largely derived from RanPB2, but it had also acquired a domain from the neighboring GCC2 gene, whose protein product contains a GRIP domain ...New therapy for HIV/AIDS eliminates needles and excessive toxicity
... similar tothe excision of jumping genes, but none had matched one of itscharacteristic oddities: As the unwanted DNA is being removed, theremaining DNA forms a tiny loop.Unexpectedly, when Hermes is being cut out of the DNA, the leftover DNAalso forms a hairpin loop, temporarily doubling back on itself,......nformation resides there," says Chen. First, they had to breach the nuclear membrane, which has pores that are only about 20 nanometers wide. To fit through these tiny slits, Chen and Gerion used an especially compact cadmium selenide/zinc sulfide quantum dot coated with silica. Next, they stole a trick...