Timing is everything: First step in protein building revealed
...lex can the ribosome start making proteins."No one had any idea when eIF1 was released from the ribosome,...ere surprisedand pleased by what we saw next."They had expected -- or at least hoped -- to see a shift in the colorof light once the RNA was mixed in. Inst...Tiny particles could solve billion-dollar problem
...face of the particle. Pure palladium nanoparticles had 24 percent of the metal on the surface. In the gold-palladium nanoparticles, 100 percent of the palladium atoms are accessible for reaction. "We've documented the efficiency of these catalysts in breaking down TCE, and the next step is engineering a...Plants, animals share molecular growth mechanisms
...ausing altered growth. The researchers previously had learned that a large protein complex, known as WAVE, activated ARP2/3, but they didn't know specifically which WAVE protein was the actual switch. Their latest research showed that a WAVE protein they've dubbed DISTORTED3 (DIS3) turns on APR 2/3, whi...Researchers Uncover Key Step In Manufacture of Memory Protein
...n earlier study, another team of NICHD researchers had shown that mBDNF is essential for the formation of long-term memory, the ability to remember things for longer than a day. “Understanding how BDNF is made may help us to better understand the learning process, perhaps leading to better treatments fo...Male circumcision reduces risk of HIV transmission from women to men
...lated to be .0063, orone in 160. Uncircumcised men had a more than two-fold increased riskof infection per sexual act compared with circumcised men--one in 80versus one in 200. Past studies have also found greater HIV infectionrisk for uncircumcised men. Unlike those studies, however, the presentstudy wa...Another Look Finds Promising Proteomics Test is Not Biologically Plausible
...linded samples, the test detected all patients who had ovarian cancer and only misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Canc...Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
...ector, Gene ExpressionMarketing at Affymetrix. "We had great success with this program lastyear. By providing the plant and animal community groups with a single,standardized platform for gene expression research, they can easilycompare results, build reliable databases and move science forward morequick......linded samples, the test detected all patients who had ovarian cancer and only misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Canc...Cracking the olfactory code in bees
...linded samples, the test detected all patients who had ovarian cancer and only misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Canc...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...xtremely high; microarray datafrom the RNA samples had the highest correlation values, followed bythe cell lines, and then finally the tissue samples. This was notsurprising, as RNA required the fewest steps of preparation, whiletissues required the most. The between-lab correlation values decreasedsligh...Signaling protein builds bigger, better bones in mice
...linded samples, the test detected all patients who had ovarian cancer and only misdiagnosed three healthy individuals. But among others who subsequently tested the study’s data for reproducibility were Baggerly and his colleagues (Kevin Coombes, Ph.D., and Jeffrey Morris, Ph.D., from M. D. Anderson Canc...Scientists detect probable genetic cause of some Parkinson's disease cases
... 34 of the 767 people who hadinherited the disease had at least one copy of the mutated gene.Similarly, the team detected one copy of the mutation in 8 of 482people with Parkinson's disease, but who didn't report a family historyof the disease. The Parkinson's Study Group is a non-profit,cooperative grou...Newly discovered virus linked to childhood lung disorders and Kawasaki disease
...imensfrom 895 symptomatic children under age 5 who had tested negative forother viral infections. They fo...breathing, abnormal breath sounds, and hypoxia; 35 had an underlyingcondition, such as prematurity (19 patients). Indeed, 11 of thoseinfected with the new ...Ancient olfaction protein is shared by many bugs, offering new pest control target
.... A group of Rockefeller University scientists who had previously identified a key gene essential for the...species. Research by Leslie Vosshall's laboratory had previously shown that of 62 odorant-receptor proteins expressed by fruit flies, 61 are exclusively e...Bound for destruction: Ubiquitination protects against improper Notch signaling
...eptor from activation.Recent studies by other labs had shown that a number of stages in theNotch cascade ...tly bindto proteins marked for degradation), as it had previously been shownthat Nedd4 plays a role in the processing of other types oftransmembrane protei...Research on Worms Yields Clues on Aging
...earchers found that an epilepsy drug used inhumans had the unexpected effect of prolonging the life span ...s that control body movement.Scientists previously had found genetic mutations in C. elegans thataffect both the nervous system and life span. The research...Cytoplasm affects the number of vertebrae in carp-goldfish clones
...ldfish have 26 to 28. Six of the seven cloned fish had between 26 and 28 vertebrae; one had 31. Although the initial rate of success in producing carp-goldfish clones is low--seven offspring ...Found: Missing sequence of the human Y chromosome
...hromosome-linkedphenotypes. Rappold and colleagues had previously physically mapped theGCY locus, which is thought to be the genetic determinant ofsex-related stature differences in humans and is in close proximity tothe Y centromere. In addition, the GBY, or gonadoblastoma locus, whichis responsible for......eaths in Cabinda, Luanda and Uige. All these cases had originated in Uige Province. Ten of these cases have been laboratory confirmed by the Centers for Disease Control and Prevention (CDC), Atlanta, USA. The team from WHO, including experts from the Inter-country programme for southern Africa, the Regi......f ocean acoustics right now,?says Clark. “The Navy had heard the whales for years but hadn’t focused on the significance of their low voices. To me it was like —ohmygawd!?/p> Access to the U.S. Navy’s underwater listening systems took researchers from fixed-point observations such as ships, to synopt...