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Tag: "had" at biology news

Low level of extinction during ice age linked to adaptability

...sed by the loss and lack of recovery of those that had existed in narrow latitudinal ranges." Powell bel... those brachiopods which eventually became extinct had adapted only to small temperature changes, and thus did not survive," he said. "The other competing ...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

... control excitation of nerves, the reason for leak had not previously been understood. The first human clone of this channel, K2P1, generated a good deal of excitement, Goldstein said, but no one could learn much about it because it always seemed to be mute. "This discouraged a lot of people." The prob...

Stem cells from brain transformed to produce insulin at Stanford

...orked is a bit surprising. Until recently, people had though that stem cells taken from the brain would ...again released insulin. After four weeks the cells had survived, continued to produce insulin and had not changed into other cell types or formed tumors. ...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...fect hamsters but not humans. The new mouse strain had the same amino acid sequence as the original mouse strain but completely different infectious capabilities. With the help of atomic-level microscopic observation of prions in humans, mice, and hamsters, Jones and Surewicz discovered that it is the s...

New component of the 'brakes' on nerve regeneration found

...nerve impulses. Researchers knew that CNS neurons had receptors on their surface that accepted the inhib...ed-on inhibitory signaling within the neuron. They had also shown that a protein called p75 could function as a component of the complex of proteins that m...

Increased risk of osteoporosis associated with gene that one in five people have

...at the gene could also affect bone density. No one had ever investigated that possibility, so we set up a... of the general population, was found in women who had significantly lower blood estrogen levels and higher levels of urinary estrogen breakdown products t...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...ny antibiotics that initially came out have either had their dosages changed because they were excessive or had them increased because they weren’t enough.?/p>...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...vability of Bb within its hosts. The research team had hypothesized that the elimination of the gene would somehow impact the pathogenesis of Lyme disease in mammals, but they found no evidence of that. Knockout bacteria not only survived within mice, but also produced Lyme disease in the animals. "That...

HIV-1 spread through six transmission lines in the UK

...ences, also suggest that antiviral therapy has not had a significant impact on the growth of the epidemic... exponential growth phase, the transmission chains had an average growth rate of a doubling of the number of people infected each year, similar to that est...

Multi-purpose protein regulates new protein synthesis and immune cell development

... lacking both copies of IRE1 died before birth and had fewer hematopoietic stem cells ?precursor cells wh...IRE1 knock-out embryos into mice whose bone marrow had been destroyed by radiation. He found that stem cells deficient in IRE1 could reconstitute all types...

Light therapy may combat fungal infections, new evidence suggests

...virulence in mice, they reported. Earlier studies had linked the genes to light-sensing in another dista...ing genes more than 400 million years ago may have had major significance for fungal colonization of land, at a time when UV irradiation was particularly i...

Gray wolves maintain the food chain in winter

Climate change has already had dramatic effects on individual species, with disruptions in range, reproductive success, and seasonal phenomena like migration. But, in a new study from the open-access online journal PLoS Biology (www.plosbiology.org), Christopher Wilmers and Wayne ...

Marburg haemorrhagic fever in Angola update

...mocratic Republic of Congo from 1998 through 2000, had a case fatality of 83%. Two factors make the rapid detection of outbreaks of Marburg haemorrhagic fever difficult: the extreme rarity of this disease and its similarity to other diseases seen in countries where deaths from infectious diseases are co...

New insight into regulation of blood stem cells

...d cells. Most surprisingly, the c-Myb mutants also had a dramatic increase in the total number of HSCs, suggesting that part of the normal function of c-Myb is to hold HSC multiplication in check. These data suggest that c-Myb is a key regulator of hematopoiesis and acts at many distinct points to contr...

Promising new West Nile therapy cures disease in mice

...as five days after infection, when West Nile virus had entered the brain, and it could still cure them," ...ure tests than antibodies obtained from people who had recovered from West Nile virus infection. ...

Alzheimer's cognitive decline slowed

...amined the brain tissue of a study participant who had died and found robust growth of extensions from th...d deep within the brains of the eight patients who had volunteered for the study. The human clinical trial was undertaken following extensive studies in p...

Nanoparticles offer new hope for detection and treatment

...ight be ten to a thousand times higher than if you had administered the drug systemically," Lanza says. The nanoparticles also may permit more effective follow up, because a doctor could use them to discern whether a tumor was still growing after radiation or chemotherapy treatments. Although this stud...

Birds brains reveal source of songs

...true to the old standards. Some years ago, Bottjer had observed that disabling a young finch's AFP circui...abble arose in the first place. For years, nobody had followed up on that question. "We framed the question in a different way," Fee says of his research...

Survey finds silver contamination in North Pacific waters

...e toxic to marine life, this contamination of what had been considered relatively pristine waters highlights the increasingly global impact of industrial emissions from Asia, the researchers said. "The most likely source of the silver contamination is atmospheric emissions from coal burning in Asia," sa...

Buying Time Through Hibernation on Demand

...eartbeat, no respiration, and her body temperature had fallen to 57 degrees Fahrenheit (normal is 98.6 F)...ze to death. Before she was resuscitated her heart had stopped beating for two hours and her temperature had plunged to 61 F. "Understanding the connectio...

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