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Tag: "guide" at biology news

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

... assimilated into large multiprotein complexes and guide those molecules to destinations in the cell where they turn off genes. "The size of these small RNAs is a determinant of their function," Hannon explained. "If the RNAs are too big or too small, they don't make it into the effector complexes." Thro...

Supersized 'island' of resistance genes discovered in an infectious bacterium

...iotic resistance," Claverie said. "This work will guide a future international effort on identifying all major A. baumannii resistant strains throughout the world, and help follow the emergence of new strains and understand their mode of evolution." ...

Zebra finches remember songs dad sang

...r's song is stored first, and that it may serve to guide the vocal learning process. The paper is titled "E... the brain and how the stored memories are used to guide the development of vocalization." ...

Chemical signaling helps regulate sensory map formation in the brain

...ggested that two such forces would be necessary to guide axons as they establish the connections that relay...tly showed how members of the Wnt family served to guide pathfinding axons up and down the spinal cord by attracting or repelling receptors on the growth con...

Secrets of the sea yield stronger artificial bone

...earchers thought of sea ice. "We allow nature to guide the process. Seawater can freeze like a layered material, so why not use this property to cast ceramics that mimic nacre," says Antoni Tomsia of Berkeley Lab's Materials Sciences Division, who developed the composite with fellow Materials Sciences Di...

Common molecular 'signature' identified in solid tumors

...rowing the list of the most active ones provides a guide to directing future research. "We know that there are hundreds of miRNAs, and some of them may have multiple gene targets. Finding the ones that appear over and over again in various forms of cancer will help us design new and better interventions,...

Cincinnati surgeons report new treatment for often-fatal injury

...ent provides an easy-to-see 'scaffolding' that can guide the surgeon to more accurately secure the extender cuffs and create a strong seal." Once in place, the dual lining supports the weakened vessel walls and allows blood to continue flowing through the aorta without applying pressure to damaged area. ...

Progress being made in exploring potential use of stem cells to treat heart disease

...llenges ahead: Developing the ability not only to guide and expand stem cells into the cardiac lineage but also to repress alternative cell fates Developing methods for safe delivery and proper integration of stem cells within patients' heart tissue to avoid such complications as arrhythmias (irregular ...

Parkinson's disease mechanism discovered

...ist and her colleagues believe their findings will guide the search for new drugs that suppress alpha-synuclein toxicity by enhancing the machinery of ER-to-Golgi transport. Thus, she said, they have already conducted a screen of 150,000 compounds for those with therapeutic potential. "We have found compo...

Adult stem cells are touchy-feely, need environmental clues

...al messenger signals that are generally thought to guide stem cells through the process of differentiation,...nce, soft microenvironments, that mimic the brain, guide the cells toward becoming neurons, stiffer microenvironments, that mimic muscle, guide the cells tow...

Scientists aim to thwart use of flu as bioweapon

...mpletely," said Wu. "Mathematical models will help guide flu experts to ask the right questions, so that we understand it more thoroughly than we do today. Understanding exactly what is happening should help scientists evaluate how the virus will respond to drugs designed to treat an infection." Since flu...

Seeing the serpent

...d grasping hands and feet, and use their vision to guide reaching and grasping. Scientists have thought that these characteristics evolved together as early primates used their hands and eyes to grab insects and other small prey, or to handle and examine fruit and other foods. Isbell suggests instead tha...

Breast stem cells have features similar to 'basal' tumors

...elp define the subtypes of breast cancer; and also guide currentapproaches to therapy. The WEHI team, together with the Eaves group in Vancouver, have found that the breast stem cell in mice is 'triple negative' for oestrogen, progesterone and Her2receptors but does express certain 'basal cell' markers....

New GI technologies improve internal organ visualization

...oscopic ultrasound to visualize the heart and help guide interventions. This study by researchers at Ho...tect abnormalities in the GI tract. Using EUS to guide them, researchers punctured the myocardium and aortic valve or coronary artery in the six pigs; thre...

Light guides flight of migratory birds

...gbirds use multiple sources of directional cues to guide their seasonal migrations, including the Sun, star patterns, the earth's magnetic field, and sky polarized light patterns. To avoid navigational errors as cue availability changes with time of day and weather conditions, these "compass" systems must ...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...lecular characteristics of each patient's tumor to guide treatment decisions," said Geoffrey Ginsburg, M.D., Ph.D., a professor of medicine and co-author of the study. Eventually, physicians will use genomic tests not only to predict patient outcomes, but also to select the individual drugs that will bes...

New roles for growth factors: Enticing nerve cells to muscles

...nth of attractive and repulsive chemical cues that guide them to their target. While several recent studi...ironment, explains Pfaff, "Most external cues that guide immature motor neurons during embryonic development will be missing." Hence the need to identify axo...

Polynesia explorers created worldwide web of scientific knowledge

...ed their courses using Linnaeus as their botanical guide and Jean-Jacques Rousseau as their intellectual guide. The first wave of travelers expected to find the same "natural" societies in Polynesia that had been discovered earlier in the Americas and "became the stuff of European stereotypes," Liebersohn...

Loosen up, DNA: Leukemia gene changes genetic packaging

...vering the major themes, and then using those as a guide when studying people directly. ...

Large-scale genomics project will hunt genes behind common childhood diseases

...hood diseases, to use this diagnostic knowledge to guide physicians to the most appropriate therapies. In addition, we plan to form strategic partnerships with biopharmaceutical companies to develop novel therapeutics," said Dr. Hakonarson. Tailoring treatments to a patient's genetic profile represents a...

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