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Tag: "guidance" at biology news

FDA Warns Consumers Not to Use Home-Use Diagnostic Kits Marketed by Globus Media

... importation of the Globus Media devices, provides guidance as to their detention and refusal of admission into the U.S., and also advises U.S. Customs officials about these products. ...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...found in both worm and fly that is involved in the guidance of nerve cell axons to their synaptic targets, or junctions, with other nerve cells. The process, considered an initial step in the development of the central nervous system, would not be needed by lower organisms, such as yeast, which don't have ner...

Cerebral navigation: How do nerve fibers know what direction to grow in?

...to give insight into how the various steps of axon guidance are controlled." The first paper found that when ephrin binds to Eph receptors on the axon, it activates a protein called Vav2 in the cell's growth cone. Activation of Vav2 induces the cell to engulf the ephrin-Eph complex, breaking the bond between...

Roche clinical trial registry and results database launched

...dical Association on ethical principles to provide guidance to physicians and other participants in medical research involving human subjects. Roche also strictly follows the rules of good clinical practice (GCP), which ensure the protection of patients?safety and rights. ...

FDA Works To Speed The Advent Of New, More Effective Personalized Medicines

...and Drug Administration (FDA) today issued a final guidance titled "Pharmacogenomic Data Submissions." Pharma...ble drug therapy and dose from the start. Both the guidance and a new Web page are part of a broad effort underway at FDA to foster pharmacogenomics during drug...

Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments

..."Our findings identify one of the first endogenous guidance molecules for migrating neurons in the adult brain," Zhou said. "We are learning that molecules, like PK2, which direct the movement of neurons are crucial for neuronal replacement, and they demonstrate how adult stem cells might be manipulated for t...

Leading scientists rank endangered dolphins, porpoises most in need of immediate action

...s Cetacean Specialist Group. "It's crucial to give guidance to agencies and organizations on how they should invest their resources for bycatch mitigation." Between 1993 and 2003, fisheries in the United States introduced changes that reduced cetacean bycatch to one-third of its previous levels. But so far l...

Canada's first embryonic stem cell lines

...s Cetacean Specialist Group. "It's crucial to give guidance to agencies and organizations on how they should invest their resources for bycatch mitigation." Between 1993 and 2003, fisheries in the United States introduced changes that reduced cetacean bycatch to one-third of its previous levels. But so far l...

Novel targets found for the development of drugs to complement, or replace, statins

...s Cetacean Specialist Group. "It's crucial to give guidance to agencies and organizations on how they should invest their resources for bycatch mitigation." Between 1993 and 2003, fisheries in the United States introduced changes that reduced cetacean bycatch to one-third of its previous levels. But so far l...

Virulizin granted orphan drug status in Europe

...s Cetacean Specialist Group. "It's crucial to give guidance to agencies and organizations on how they should invest their resources for bycatch mitigation." Between 1993 and 2003, fisheries in the United States introduced changes that reduced cetacean bycatch to one-third of its previous levels. But so far l...

Gradient guides nerve growth down spinal cord

...iven down the cord, away from the brain, under the guidance of a receptor, known as Ryk, with very different t... the hand or foot. Zou and colleagues studied the guidance system used to assemble this complex network in newborn mice, where corticospinal axon growth is sti...

Scientists and engineers apply nature's design to human problems

...ffice of Naval Research on understanding olfactory guidance in crabs. The Navy was interested in this process because it wanted to build autonomous devices with a similar capability, he explained. Then, earlier this year, Yen, Weissburg and Professor of Industrial and Systems Engineering Craig Tovey studied...

Researcher says flu responders can learn from 1918 epidemic

...today." Higgins' research has been done under the guidance of three Lehigh history professors: Roger Simon, John Pettegrew and John Smith, as well Dan Wilson, professor of history at Muhlenberg College. In each case, Higgins said, the professors have helped him focus on a component of the flu epidemic to gai...

New cell transplantation technique restores insulin production in diabetics

...iety of North America (RSNA). "We used ultrasound guidance to inject donor cells into the portal vein of diabetic patients, which is accessed through the skin," said co-author Saravanan Krishnamoorthy, M.D., radiology resident at the University of Minnesota in Minneapolis. "This is a safe method of cell tran...

Minimally Invasive Cancer Treatments Highlighted

...radiologists are uniquely skilled in using imaging guidance to deliver targeted cancer treatments throughout the body non-surgically, through the blood vessels or other pathways. Highlights of the Symposium Include: Treatments for Liver Cancer (Monday, November 28) Although surgery provides the best chance...

Magnetic probe successfully tracks implanted cells in cancer patients

...with MRI-compatible injection systems to allow MRI guidance of injection in large animals. The current clinical trial builds on Bulte's earlier work tracking magnetically labeled cells in animals. Four years ago, he and colleagues reported that stem cells containing so-called magnetodendrimers could be follo...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

...isory Board for Biodefense (NSABB), which provides guidance and advice on the implications for dual use research and publication," Kennedy said. To make the virus, the researchers used an approach called "reverse genetics," which involves transferring gene sequences of viral RNA into bacteria and then insert...

Watch your step when the going gets rough

...d your slipping or twisting an ankle. "This visual guidance mechanism could also help gymnasts on the beam, or acrobat walkers on a tightrope, as in these situations accurate foot placement becomes crucial," says Reynolds. ...

Low-cost drug gaining favor for use in HIV-infected children in poor countries

...o be released early this year -- will provide some guidance for countries as they make their own decisions, Vitória said. The recommendations include guidelines on monitoring toxicity and when to begin cotrimoxazole treatment given the child's age, whether the patient has symptoms of HIV disease and the stre...

A new focus for the mechanism of nerve growth

... thought to play a key sensory role in growth cone guidance -- suggesting actin filament recycling and signaling may be intimately related. The team is now investigating the implications of these findings for control of nerve growth, with particular interest in repair of spinal cord nerves after injury. ...

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