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Tag: "guardian" at biology news

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

... Researchers found that the P-gp system, an extra guardian located at the blood brain barrier that usually keeps anticancer drugs out of the brain, intercepted some of the JV-1-36 that was injected into mice but let much of it pass into the brain to treat cancer. "The blood brain barrier is set up to very c...

New clues to the dark side of a key anti-tumor guardian

...dence that despite the protective role of p53 as a guardian against tumor formation, normal levels of p53 activity--at least in some cell types--may indeed contribute to aging and decreased lifespan. The p53 protein is known to be a critical player in our body's natural defense against cancer--it is absent ...

Study pinpoints protein's role in cancer spread

...K, said: "p53 is a crucial protein that acts as a guardian of the normal cell. Its failure to do its job properly is associated with many types of cancer. If p53 is being destroyed by another protein in a cancer cell, then it offers an excellent target when designing new anti-cancer drugs. This research sugg...

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