Natural tumor suppressor in body discovered by UCSD medical researchers
... called Akt that controls the balance between cell growth leading to cancer and cell death that prevents tum...ug that turns on PHLPP, so that it suppresses cell growth caused by Akt, could be a potential cancer therapy," said the study's senior author, Alexandra C. Ne...Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed
...lso influence pattern formation -- Wnt, fibroblast growth factor and Notch -- and found that none of them was responsible for coordinating the antero-posterior and left-right axes. However, blocking the retinoic acid pathway generated an uneven distribution of tissue on the right and left halves of the body...Massey Cancer Center researcher helps to identify a piece of the cancer puzzle
... and characteristics of proteins involved in tumor growth and development, researchers can identify therapeutics that may eventually lead to cures for cancer." ...Key to elephant conservation is 'in the sauce'
...eutsch, director of WCS' Africa Program. "With the growth of human populations in the Zambezi Valley and beyond, people and wildlife come into more frequent contact than before. Elephant Pepper products are a working example of how the survival of elephants can be reconciled with the livelihoods of farmers....Cancer related gene p53 not regulated as indicated by previous tissue culture research
... of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer. Not surprisingly, the regulation of this vital safeguard has been studied in great detail for many years but mainly in tissue culture, or in vitro, mo...Discovery could be key to bioterrorism defense
...entral nervous system development and blood vessel growth in the embryos of humans and other mammals. Broder and his team are among only a handful of scientists focusing on the viruses, which have been under investigation by USU researchers since 2000. Broder is a principal investigator on one of six proje...Research on antibiotics receives historical recognition
...taminant on a Petri dish culture had inhibited the growth of bacteria. Streptomycin was the third antimicrobial agent isolated under Waksman's direction at Martin Hall at Cook College, Rutgers University. Streptomycin, however, was the first agent not toxic to humans, and it attacked a type of bacteria res...The making and breaking of microtubules
...cally as "dynamic instability," this ongoing rapid growth and shrinkage is key to the diverse workings of mi...igned and targeted to put a monkey wrench into the growth of cancer cells. "Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembl...Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
...urrently injectable protein drugs such as insulin, growth hormone, and erythropoietin, a medication to increase red blood cell counts." Recombinant DNA technology has and will enable the pharmaceutical industry to produce safer, more pure and more effective versions of therapeutic proteins, Shen adds. "Si...Fungus-farming termites descend from an African rain forest Eve
...ring those domesticated fungi a constant supply of growth substrate, and humid, highly buffered, rain forest like climatic conditions in their nests, termites have been able to export this rain forest process into the savannas. The marrying of termites and fungi in a mutualistic symbiosis has thus allowed b...Combination therapy leads to partial recovery from spinal cord injury in rats
...iated stem cells with gene therapy can promote the growth of new "insulation" around nerve fibers in the dam... treatment, which mimics the activity of two nerve growth factors, also improves the animals' motor function and electrical conduction from the brain to the l...Scientists inhibit cancer gene
...er-causing gene that has been shown to promote the growth of cancers in the pancreas, colon and lung, as well as thyroid cancer and leukemia. Attempts to inhibit activated Ras have had limited success until now, but the Huntsman Cancer Institute researchers explain that they have discovered an enzyme that,...Proteomics brings researchers closer to understanding microbes that produce acid mine drainage
...he community, and then what are the feedbacks from growth of these organisms that result in changes in the environment," Banfield said. "The proteomic approach will allow us to begin to understand how organisms change their behavior in response to the presence of other organisms and when their physical and ...New method shows it is possible to grow bone for grafts within a patient's body
...have all failed. Recent attempts to stimulate bone growth within the body--in vivo--have had limited success...ut having to coax the bone to grow by applying the growth factors required by previous in vivo efforts. Furthermore, they found that the new bone can be detac...Researchers grow stem cells from human skin
...n the laboratory. The scientists used hormones and growth factors to coax the stem cells into becoming fat, muscle and bone cells. When the differentiated cells were seeded onto three-dimensional molds and implanted in mice, they maintained features consistent with bone, muscle and fat tissue. "Our study s...Researchers extend mouse lifespan by protecting against free radicals
...ake. Another method relied on the restriction of a growth factor, but a side effect was that the mice suffered from dwarfism. However, neither of those methods of elongating the mouse lifespan was clearly connected to the free-radical theory of aging. A group of scientists led by Dr. Peter Rabinovitch, pro...Modified collagen could yield important medical applications
...red protein could help deliver drugs and shape the growth of engineered tissueCollagen often pops up in beau...Yu says. Still other medical uses are possible. A growth factor joined to collagen could encourage new cells to multiply. An antibiotic attached to collagen ...Unusual antibiotics show promise against deadly 'superbugs'
...red protein could help deliver drugs and shape the growth of engineered tissueCollagen often pops up in beau...Yu says. Still other medical uses are possible. A growth factor joined to collagen could encourage new cells to multiply. An antibiotic attached to collagen ...... of joint space, loss of protective cartilage, and growth of bone cysts (or osteophytes). Interestingly, Wnt-7b was strongly upregulated within joints at sites of disease manifestation: mainly in synovium of RA but in synovium, cartilage, osteophyte, and bone of OA. In addition, the findings that Wnt-7b wa......easing cancer cell proliferation rates and causing growth arrest. In this study, the team first used HPV infected epithelial cells and normal human epithelial cells, which are natural hosts for both AAV2 and HPV. In cultures infected with both AAV2 and HPV, the team found that after six days, all HPV infec...