Changing ecosystems throw scientists mega-challenges
...f water," it says. With continued human population growth and the uncertain impacts of of environmental change, the report states, ensuring an adequate quantity and quality of freshwater for sustaining all forms of like is a growing challenge. " Integrated, multidisciplinary, and multi-scale, water-related ...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
...nlinearity means that different sets of biological growth rules will apply in each different physical enviro...ent theory using fixed production functions (fixed growth rules) and fixed harvest targets is no longer supportable," says Sugihara. "The beguilingly simple s......" said Hicks. In the snake, the rapid ventricular growth coincided with an increased production of the musc...isms leading to cardiac remodeling and ventricular growth in other animals, including humans. Hicks' research is supported by the Integrative Organismal Biol...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
... in rodent models of E. coli infections halted the growth of antibiotic resistance. Three days after being subjected to antibiotics, the rodents showed no level of resistance to rifampicin or ciprofloxin, when they harbored a variant of LexA that was catalytically inactive. In control experiments, the roden...Cousin of Asian super termite invades Florida
... bait system has a chemical called noviflumuron, a growth regulator that prevents termites from molting, thereby reducing the ability of the worker population to sustain underground colonies. The chemical has a low toxicity to humans and the environment. Less than one gram kills an entire colony containing ...'Smart drug' targets deadly brain cancer
...urable form of recurrent brain cancer slowed tumor growth in more than one-third of the 65 adult patients who tried it. The same research team also developed a screening technique to help predict which patients will respond best to this treatment. Mayo researchers will present these findings at the 2005 Am...Characterizing Skin Cancer by Microarrays
...ne expression pattern characteristic of the radial growth phase, which implies that both radial and vertical melanomas can metastasize. The authors identified over 2,000 genes that distinguished the stages of melanoma progression. The authors say that their results will provide a basis for developing new m...Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage
...rength determines the level of expression of early growth response (Egr) proteins, with cells choosing the gamma-delta lineage expressing far greater quantities of Egr proteins than those adopting the alpha-beta lineage," explained Wiest. "Egr proteins regulate which cellular genes are turned on or off so w...Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
...use embryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a ...n the study, ES cells were treated with fibroblast growth factor for seven days prior to injection. As expected, this resulted in ES cells differentiating int...Engineers improve plastic's potential for use in implants by linking it to biological material
...ules that promote nerve regeneration, blood vessel growth or other biological processes. In the study led b... to polypyrrole in the future that stimulate nerve growth or serve other functions," said Schmidt, an associate professor of biomedical engineering at the uni...Researchers pioneer new gene therapy technique using natural repair process
...eventually given back to the patient, spawning the growth of healthy blood cells, Dr. Porteus said. ...Researchers Closer To Helping Hearing-Impaired Using Stem Cells
...rrow stromal cell transplantation to stimulate the growth of the nerve cells that are often missing from the inner ears of patients with profound hearing loss. “Sonic hedgehog and retinoic acid are molecules found in embryonic tissues, but not in adult tissues,?said Dr. Hashino. “This suggests that treatin...Function of new cancer genes discovered
...protein is mutated. This results in increased cell growth and the occurrence of tumours. An important implication of this research is that inhibition of the NF-kappa B route in cylindromatosis patients could be an adequate form of treatment. Aspirin is a well-known inhibitor of this route and a clinical st...Unlike other mammals, newborn dolphins and orcas stay active 24/7 during first months of development
...t respiration at the surface, and facilitate rapid growth of brain and body and related behavioral development. "Somehow these seafaring mammals have found a way to cope with sleep deprivation, facilitating rather than hindering a crucial phase of development for their offspring," said Dr. Jerome Siegel, p......tes of these species were generally very high, the growth rates were very slow and unpredictable. Moreover, ...tities of the substance needed are small or if the growth can be optimised in combination with other reared organisms. Nicole de Voogd's research was funded ...Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
...r compound, PTSB, shown in CMLD studies to inhibit growth in the test organism (baker’s yeast) as well as in human small lung carcinoma cells. Their algorithm predicted, and subsequent experiments verified, that PTSB acted on thioredoxin and thioredoxin reductase, findings that not only validate the tool’s...Tamoxifen-like drug suggests new ways to selectively block estrogen
...e uterus, acting like estrogen to stimulate tissue growth and increasing the risk of uterine cancer. A newe...agonist. As a consequence, GW 5638 can inhibit the growth of breast cancers that have become resistant to tamoxifen. It may also be more effective than tamoxi...Major new UNC-based drinking water study suggests pregnancy fears may be overstated
...e was some indication, however, that reduced fetal growth might be associated with higher exposure levels." Particularly helpful to the study were the women who participated and the participating water work utilities, he said. "We are grateful to all these people since we could not have done this useful s...New understanding of cell movement may yield ways to brake cancer's spread
...r of outside cellular attractants like chemokines, growth factors and other molecules. Meanwhile at the hind end of the cell, enzymes degrade the PIP3 lipid, creating a gradient from one end of the cell to the other. It is this PIP3 lipid gradient that sets the cell into motion toward the right direction. ......earch shows how EBNA1 interferes with natural cell growth regulation by binding to a particular protein in cells, causing them to continue growing and therefore increasing the risk of becoming cancerous." Frappier explains that all cells contain the two proteins ?p53 and USP7 ?that work together to regulat...