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Tag: "growth" at biology news

Researchers identify target for cancer drugs

...romotes cell division, often contributing to tumor growth as a result. However, as long as it stays within the cell cytoplasm, it remains relatively inactive. That's because the tumor-suppressor protein PTEN keeps Akt in check by destroying lipids in the cell membrane that normally draw Akt to the surface. ...

Plant hemoglobins: Oxygen handlers critical for nitrogen fixation

...monia, which is subsequently used by the plant for growth and colonization of nitrogen-poor soils. Symbiotic nitrogen fixation is important for sustainable agriculture and contributes millions of tons of reduced nitrogen to crops and pastures each year. As reported this week, researchers led by Dr. Michael...

Scientists rid stem cell culture of key animal cells

...ed the molecular interactions within the stem cell growth medium. He discovered that, in certain conditions, a protein known as fibroblast growth factor 2 (FGF2) accomplishes the same critical role that feeder cells are thought to play: ensuring ...

U-M scientists find genes that control growth of common skin cancer

...er Institute haveidentified genes that promote the growth and recurrence of skin cancer.Andrzej Dlugosz, M.D...treating these cancers, which generally have aslow growth rate and seldom spread or metastasize. However, untreatedBCCs can cause extensive local tissue damag...

Critical role in programmed cell death identified

...Also, if cells do not die on schedule, unregulated growth can lead to tumors and other complications. "Mammalian studies that have implicated mitochondrial fragmentation in cell death have been done under rather artificial conditions, in tissue culture, not using natural cell death stimuli, " Conradt expla...

Genetically modified natural killer immune cells attack, kill leukemia cells

...mes their original number. The technique triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cells. The researchers then genetically modified the growing NK cells so they carried on their surface an artificial recep...

UCSD researchers maintain stem cells without contaminated animal feeder layers

The growth and maintenance of human embryonic stem cells in t...dy. The scientists knew that a cocktail of various growth factors and chemicals had previously been shown to modulate cellular growth and differentiation in h...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially homes to specialized immunesystem cells known as dendritic cells, and infects them. Inside,VRP-neu produces high levels of the HER2/neu protein, which thedendritic cells then display on th...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...s cells to make thousands ofcopies of the HER2/neu growth protein, says Lachman.In addition, the VRP-neu preferentially homes to specialized immunesystem cells known as dendritic cells, and infects them. Inside,VRP-neu produces high levels of the HER2/neu protein, which thedendritic cells then display on th...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...mental biology, the study of how genes control the growth and specialization of organs. In 1976, Crick moved to the Salk Institute for Biological Studies in La Jolla, California, where he took up neurobiology, his other long-standing scientific interest. He never let up in his passionate pursuit of scienti...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

Deficiencies of growth hormone and similar compounds may reduce cancer an...archers used a rat model to explore the effects of growth hormone and another compound, IGF-1 (insulin-like growth factor 1) on adult rats and found paradoxic...

DNA Recombination and Repair—A New Twist to RecA Function

...ite blood cells toward pathogens is powered by the growth of actin filaments pushing against the cells?membranes. In all cases, coherent motion implies a coordinated and polarized use of energy. Now, Julia Cox, Oleg Tsodikov, and Michael Cox present evidence indicating that filaments of the bacterial RecA ...

Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells

...tic food containers has been shown toencourage the growth of a specific category of prostate cancer cell,pot...cer depend on androgens like testosterone fortumor growth and cancer cell proliferation, said Dr. Knudsen, thestudy’s senior author. A common treatment for pr...

Breast Cancer May Be 'Uniquely Sensitive' To Inhibitors Of PI3K Pathway

...apeutics. Thispathway, which is linked to critical growth factor receptors and isinvolved in programmed cell death, is aberrant at multiple levels inbreast cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstalk between the PI3K pathway an...

Genetic Variation Visualization - From EMBL

...apeutics. Thispathway, which is linked to critical growth factor receptors and isinvolved in programmed cell death, is aberrant at multiple levels inbreast cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstalk between the PI3K pathway an...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...t inhibits destructive cell signals that drive the growth of one-third of all cancers. The scientists showed they could block the growth of cultured colon cancer cells using this new compound, called cysmethynil. Their finding, reported...

New Mixing Method for Microchip-Sized Labs

...apeutics. Thispathway, which is linked to critical growth factor receptors and isinvolved in programmed cell death, is aberrant at multiple levels inbreast cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstalk between the PI3K pathway an...

Tiny scaffolding allows stem cells to become working fat cells

...res, cells usually grow as flat deposits bathed in growth medium. While useful, these "two-dimensional" patc... is why the three-dimensional scaffolding for cell growth in the laboratory is so important. The researchers' focus on fat cells as a test bed for this appro...

Scientists identify new model Of NK cell development

...de a major discovery that sheds new light upon the growth and development of human natural killer (NK) cells, powerful but somewhat mysterious components of the body's immune system that are the first line of defense against cancer and infectious diseases. Scientists have believed for years that human NK c...

Study of genomic DNA leads to new advances in cancer diagnostics

...ch interactions must be aberrant for abnormal cell growth and metastasis to occur. Indeed, Dr. Maniotis and his colleagues found that the extracellular matrix (ECM), or the microenvironment surrounding the cell, influenced whether the cell's chromatin was sensitive or resistant to Alu I. The group also impl...

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