A genetic 'gang of 4' drives spread of breast cancer
...lls of these genes decreased both their ability to grow large aggressive tumors in the mouse mammary gland...so that the cells can penetrate the lung tissue to grow there. "These findings provide a beautiful explanation for how the genes that we identified in bre...Newborn brains grow vision and movement regions first
... that control vision and other sensory information grow dramatically in the first few months following birth, while the area that controls abstract thought experiences very little growth during the same period, University of North Carolina at Chapel Hill researchers have found. The researchers discovered...How fish species suffer as a result of warmer waters
... constant low temperatures. The latter are able to grow and reproduce only within a very limited thermal tolerance window. Investigations at the Alfred Wegener Institute show the key importance of oxygen uptake and distribution ?through respiration and blood circulation ?in setting the animals' thermal...Cancer-killing invention also harvests stem cells
... kills cancer cells and captures stem cells, which grow into blood cells, bone, cartilage, and fat. When ...pecific capture of hematopoietic stem cells, which grow (or differentiate) over time into all of the different blood cells, and the specific capture of stem...Bacteria control how infectious they become, study finds
...cate balancing act. With too little RfaH, bacteria grow too slowly. But too much RfaH, and they will die. ... the researchers found that pathogens lacking RfaH grow at much slower rates. “Cells usually don't die when RfaH use changes,?Svetlov said. “Rather, bact...Liver regeneration may be simpler than previously thought
...ntists listed all the proteins that help the cells grow and proliferate in both samples. The results were unexpected. The researchers noticed that only a few proteins were common to both processes. Proteins called transcription factors, which affect DNA in the cell's nucleus, were highly involved in ...Scientists discover new, readily available source of stem cells
...uced from the stem cells were successfully used to grow bony tissue in mice, and liver cells were able to secrete urea, which the liver produces from ammonia. The potential to generate a broad range of mature cell types is why many scientists believe stem cells have promise to replace damaged cells and...Molecular differences between early and advanced melanomas could provide new drug targets
...read on the surface of the skin and melanomas that grow vertically and invasively could provide new target...to the American Cancer Society. But when melanomas grow downward, the tumors become highly resistant to chemotherapy and radiation and the five-year surviva...New mechanism for nutrient uptake discovered
...e organisms—cyanobacteria in the ocean, fungi that grow on grapes and make our wine, plants that provide our food—and even in our kidneys, which excrete nitrogen. We also suspect other different types of transporters will be discovered to work in this way." The scientists don't yet know what triggers t...Early-stage sperm cells created from human bone marrow
... cells. These cells have previously been found to grow into other body tissues such as muscle. They cultured these cells in the laboratory and coaxed them into becoming male reproductive cells, which are scientifically known as ‘germ cells? Genetic markers showed the presence of partly-developed s...Darwin's famous finches and Venter's marine microbes
...o sample the 99 percent of all bacteria that won’t grow in the lab," explains Manning. "GOS opens a huge window into biological and genomic diversity and, within this diversity, to better understand many of the fundamentals of biology." he adds. Expanding the universe of protein families But inst...New cell type identified in cancer development
...their ultimate fate ?whether they will continue to grow into cancer or cancer stem cells, lie inactive or be eradicated by the body’s immune system. "These hybrid cells are very complex. They have properties of normal and abnormal stem cells, and do not always lead to cancer ?only some of the time, an...New molecular pathway could reveal how cells stick together
...said. Many tissues undergo remodeling as the flies grow and develop, but at least one, the breathing tubes, do not develop properly in the mutant flies. Page-McCaw calls it a "cellular adhesion defect that causes problems for the animal at the tissue level." Now she plans to find how ninjurin affects b...New biofuels process promises to meet all US transportation needs
...icles and plug-in hybrid electric vehicles." To grow enough biomass for the entire nation's transportat...cally takes more than 10 times the solar energy to grow crops than it does to produce the equivalent quantity of hydrogen possessing the same energy content...Researchers urge monitoring of bone health during chemotherapy
...f chemotherapy induced bone loss and helped tumors grow in bone. So the researchers at Washington University School of Medicine in St. Louis are recommending increased awareness of bone health during cancer treatments. The medication studied is a growth factor commonly used to help cancer patients recov...RNA enzyme structure offers a glimpse into the origins of life
...onstruct." At UC Santa Cruz, he began trying to grow crystals of the ribozyme so that he could use x-ray crystallography to determine its structure. Crystallizing RNA molecules is extremely difficult, and Robertson tried dozens of different versions of the ribozyme under different conditions before he ...New species declared: Clouded leopard on Borneo and Sumatra
...eopards are the biggest predators on Borneo. Some grow to be as large as a small panther, and have the longest canine teeth relative to body size of any cat. Sumatran tigers are the largest predators on Sumatra. Between 5,000 and 11,000 clouded leopards are estimated to live on Borneo. The total numb...New research shows that flu is a trigger of heart attacks
...nary arteries in early childhood and these lesions grow over time. Inflammation plays a pivotal role in development and growth of these lesions. Most people in Western countries live with different stages of atherosclerosis and many will never show any clinical manifestations of the atherosclerosis. Howev...HIV protein enlisted to help kill cancer cells
...AT-Bim. "Unlike most healthy cells, cancer cells grow very fast. So they are always on the verge of running out of natural ingredients like sugars, and mistakes are accumulating in their DNA," Hawkins says. "This results in signals telling cancer cells to die, but the cells don't quite have the permissi...Cheaper, better disease treatments expected from faster approach to developing antibodies
... in Nature Biotechnology. Bacteria are easy to grow in an inexpensive broth. As a result, harmless forms of the bacterium E. coli have already been used as factories to produce antibodies (protective proteins of the human body that fight viruses, cancer cells and other harmful agents). However, previo...