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Tag: "groups" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...ecules can be modified to include other functional groups that give it additional properties, Sherburn says. For instance, one highly active version of the superbowl molecule goes by the name tetrabromo-superbowl (C268H320O52Br4) due to the addition of four bromine atoms. The bromine atoms make the hole at...

Association of herpesvirus with lung disorder questioned

...n or the DNA in any of the 22 samples from the two groups with some form of pulmonary hypertension, whereas the antigen was detected in the control group of Kaposi's sarcoma tissue samples. These data suggest that human herpesvirus 8 infection is not associated with Japanese cases of primary pulmonary hype...

Man and mouse share genome structures

... believes. For example, proteins that place methyl groups on histones can, when mutated, cause leukemia. Bernstein hopes to apply the new technology to characterize chromatin structure in leukemic cells and gain insight into the molecular basis of disease. "The human genome still has many surprises lurking...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiation therapy ...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiation therapy ...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...he team terminated the quantum dots withcarboxylic groups by reacting them with mercaptoacetic acid. Then theyconjugated the quantum dots with the amine groups of stigma/stylarcysteine-rich adhesin (SCA) - a plant pollen tube adhesion protein.This labeled the ...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...s nothing outwardly different about them." The two groups of offspring ate the same chow diet, maintained a similar weight, and neither group was allowed to become overweight, eliminating this common risk factor for diabetes. The only difference was that the mothers had been fed differently during the final...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...hers at North Shore-LIJ, as well as other research groups in Bethesda, MD, San Diego, CA, and Barcelona, Spain, have identified genetic and protein markers that can predict whether a CLL patient will follow the benign or aggressive course. Some markers are not yet available for clinical use, however accordi...

Male circumcision reduces risk of HIV transmission from women to men

...differences insexual behavior did not matter: when groups of men were excluded fromthe analysis based on ethnic or religious characteristics, thedifference in probability of infection related to circumcision statusdid not change.In addition to the results on circumcision, another significant resultof the st...

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

...tyear. By providing the plant and animal community groups with a single,standardized platform for gene expression research, they can easilycompare results, build reliable databases and move science forward morequickly."Affymetrix Consortia Program arrays are developed using the samereliable design and manuf...

Genome-wide mouse study yields link to human leukemia

...S) to compare methylation patterns among the three groups of mice ?a method of using enzymes and gel electrophoresis to map tiny bits of DNA on a grid. The stretches of DNA, referred to as fragments, show up as smudgy blobs on a test film. If a fragment is dark and definite, it is not methylated. If, on the...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...oglycoside antibiotics have sugar rings with amino groups attached," explains Dr. Baker. "The N-acetyltransferase chemically modifies the sugar amino group by transferring an acetyl group to it. This inactivates the antibiotic because it can no longer fit into its target." However, in vitro biochemical ass...

Experiments provide proof of how traveling in groups protects insects

... And they can travel a mile or so a day. Why such groups of insects form has mystified humans for thousands of years. One firmly held belief was that God was punishing men and women for their sins. A more recent, scientific theory has been the "safety-in-numbers" idea -- that the small animals congregate p...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...ost genes, the HOX genes appear to be turned on in groups by massive numbers of tags. HOX genes also are deeply involved in cancer, making the findings particularly important. Some of the proteins that regulate HOX genes are capable of causing or suppressing tumors. Technological breakthrough Bernstein h...

Experiments provide proof of how traveling in groups protects insects

... And they can travel a mile or so a day. Why such groups of insects form has mystified humans for thousands of years. One firmly held belief was that God was punishing men and women for their sins. A more recent, scientific theory has been the "safety-in-numbers" idea -- that the small animals congregate p...

Open microfluidic and nanofluidic systems

...bility (PNAS 102, 1848-1852 (2005). Many research groups around the world work towards the construction of "labs-on-a-chip" in order to integrate chemical and biochemical analyzers on the micrometer or even nanometer scale. These devices will significantly change the way in which research is performed in t...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...R2/neu proteins, he says.In the experiments, three groups of seven mice were treated with threeinjections of...tcontained an influenza protein, and the other two groups received oneof two different doses of the VRP-neu vaccine. Researchers thenimplanted a HER2/neu-posi...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...R2/neu proteins, he says.In the experiments, three groups of seven mice were treated with threeinjections of...tcontained an influenza protein, and the other two groups received oneof two different doses of the VRP-neu vaccine. Researchers thenimplanted a HER2/neu-posi...

Development of portable infectious disease detector

...ping the ability to measurethe metabolism of small groups of cells and studying how they respondto drugs, to... toxins. The ability tomonitor the health of small groups of cells, however, makes it possibleto detect the presence of unknown poisons as long as they affect...

NYC's First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention

...ublic health officials, medical providers and AIDS groups to fine tune and develop aggressive, ongoing and innovative HIV prevention programs with a particular emphasis on targeting high-risk populations," said Michael Weinstein, AIDS Healthcare Foundation President. "Clearly men who have sex with men conti...

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