New findings challenge established views on human genome
...n overlapping ways not yet fully understood. In a group paper published in the June 14 issue of Nature and in 28 companion papers published in the June issue of Genome Research, the ENCyclopedia Of DNA Elements (ENCODE) consortium, which is organized by the National Human Genome Research Institute (NHGRI)...Penn researchers link cell's protein recycling systems
...age-related neurodegeneration.” Taylor and his group study fruit flies in which the proteasome is disab...we wondered, could HDAC6 be the link"” Taylor’s group showed that if the HDAC6 gene is knocked out, inducing autophagy no longer rescues the fly eyes from...In nature, proteins sweep up nanoparticles
... that remains unanswered: Why do the nanoparticles group together" Something so small should disperse throughout the mine. Instead, the metal nanoparticles form blobs that measure several microns in diameter (one micron is one-millionth of a meter). And these larger blobs anchor the nanoparticles in place....Research finds that circadian rhythms dominate all life functions
...n rhythms, and the timing of the rhythms from each group of genes that are synchronized is important." Ptitsyn also discovered alternative short and long copies of some genes oscillating in the opposite phase. These genes are essential components of leptin signaling system, responsible for the sensation ...Runners -- Let thirst be your guide
... lost during exercising, the researchers say. A group of experts in this condition has issued a number o...Sports Medicine. Verbalis says the goal of the group is to understand the biological basis of EAH, and in that way, assure that no athlete ever succumbs ...Gene responsible for common hearing loss identified for first time
... for multiple testing. Analysis of a large French group showed the same association. “Combining the data from both groups with a common odds ratio gave a very significant result, from which we were able to conclude that we were the first to identify a gene that influences the susceptibility for otoscle...Clot-dissolving agent may be beneficial in treatment of severe frostbite
...rs in our series,” the authors write. “The control group underwent 14 proximal amputations, including five below the knee. The preservation of limbs, which maximizes patient functional outcome, is perhaps the greatest benefit conferred by use of tPA in frostbite injury.” The researchers suspect tPA help...Blood-brain barrier breached by new therapeutic strategy
...o the rabies peptide through the tail veins in one group of mice, while other mice served as control groups. All the mice in the control groups died from JEV infection; in contrast, 80 percent of the mice that got the antiviral siRNA linked to the rabies peptide survived. These experiments demonstrate how ...CU study reveals why starling females cheat
...te with subordinate males from within their social group when they need help to raise their chicks. (Superb...pairs get help in raising chicks from other family group members.) This additional male then also acquires food and tends to the nestlings, which increases t...Gene therapy study shows safety and statistically significant improvement in Parkinson's disease
...f the procedure. At one year, all 12 patients as a group demonstrated a clinical improvement of 25% in the Unified Parkinson’s disease Rating Scale (UPDRS) compared to baseline (p<0.005). Nine of the 12 patients showed an average of 37% and five of these patients had substantial improvement of between ...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...m has a new food source. "Although in the same group as Clostridium difficile — the Cdiff superbug — C. botulinum has a genome that is remarkable because it is so stable," commented Dr Mohammed Sebaihia, lead author on the paper from the Wellcome Trust Sanger Institute. "Unlike Cdiff, in which more tha...'Smart' mice teach scientists about learning process, brain disorders
...called Cdk5, from the brain are continuing. The group is also beginning a search for drugs that might create the same effects without genetic manipulation and monitoring the animals’ health and behavior over time. The findings may have applications in treating post-traumatic stress disorder, where g...Ants show us how to make super-highways
...prove the performance of a majority to benefit the group as a whole. It also suggests that these benefits are a consequence of the unusual and derived foraging strategy of the army ant (Eciton burchellii). This highlights the importance of considering ecology and evolutionary history in the study of social...'Virtual autopsy' helps identify drowning as cause of death
...28 consecutive male drowning victims and a control group of 12 men who were victims of sudden death from co...lling of the stomach. No members of the control group had frothy fluid or sediment in the airways or sinuses, 11 (92 percent) had subglottic airway, trac...Researchers use MRI to predict recovery after spinal cord injury
...uded 100 patients with traumatic cervical SCI. The group consisted of 79 men and 21 women between the ages of 17 and 96. Complete motor and sensory SCI was seen in 26 patients, incomplete SCI was seen in 51 patients, and 22 patients were neurologically intact upon admission. One patient could not be classi...How brain pacemakers erase diseased messages
... activity seen in people with tremors, assembled a group of these model cells and watched what would happen when the cells were electrically stimulated at various rates and intensities. In addition to showing how the therapy works, their model of neurons in action also revealed that stimulation delivere...'Virtual Patient' to simulate real-time organ motions for radiation therapy
...), co-founded by Xu. The collaboration with the group in Texas came about when Xu's former student, Chengyu Shi, a clinical medical physicist, and Martin Fuss, a radiation oncologist, expressed their interests to develop better radiation treatment by accounting for lung movement. Xu contacted De, who ha...Scientists discover 5 new species of sea slugs from the Tropical Eastern Pacific
...alacological Bulletin. __IMAGE_2 Nudibranchs—a group of mollusks lacking outer shells—have developed sophisticated chemical defense mechanisms, which is particularly important because promising industrial and medicinal products have been isolated from known species. New species may provide cures for d...Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?
...like vaccinia, orthopox and monkeypox virus. (This group includes some government employees, some emergency workers military personnel and researchers). ...Statin treatment improves spatial memory in mouse models of Alzheimer's
.../kg Simvastatin for seven days, while half of each group only received saline. Each day the mice had two swimming trials in the water maze, giving them a chance to learn how to reach a platform. Food was always available and safety makes taken during the entire trial. On the seventh day the animals were...