Discovery of an HIV inhibitor in human blood points to new drug class
... Germany. "That's a big advantage." Kirchhoff's group also provided evidence that HIV-1 does not easily develop resistance to VIRIP, at least in cell culture. Furthermore, their collaborators led by Wolf-Georg Forssmann of IPF PharmaCeuticals GmbH and Hannover Medical School found preliminary evidence s...The origin of the brain lies in a worm
...een in animals today is what Detlev Arendt and his group study at EMBL. To do so, they investigate the nerv...ng a prototype invertebrate CNS." Arendt and his group investigated how the developing CNS in Platynereis embryos gets subdivided into the regions that lat...No sex for 40 million years? No problem
A group of organisms that has never had sex in over 40 million years of existence has nevertheless managed to evolve into distinct species, says new research published today. The study challenges the assumption that sex is necessary for organisms to diversif...Parasite infection may benefit MS patients
...were three clinical relapses of MS in the infected group and 56 relapses in the uninfected group. Only two infected patients showed minimal Expanded Disability Status Score changes (EDSS is used to measure disability due to MS) that lasted less than three months, while the other 10 had no changes in EDSS s...Uganda's mountain gorillas increase in number
...et out with the intention of counting every family group in the population, a method possible only with sma...re. Particularly encouraging, however, is that one group of gorillas are starting to use the northern sector of the park for the first time in living memory....Scientists uncover new target in cancer mutation puzzle
...olved in half of all human tumors, Land's research group is taking the opposite approach. They are looking for ways to stop tumors by interfering with features of cancer cells dependent upon p53 and Ras mutations. For cancer to develop, several mutations must arise and collaborate within a single cell. ...Buckyballs used as 'passkey' into cancer cells
...s did not pass through the cell walls. Barron's group collaborated with Yang's brother, Baylor College of Medicine assistant professor Jianhua Yang at Texas Children's Cancer Center, and found the Baa-containing peptides could mimick viral proteins and pass through the walls of cancer cells. The peptide...DNA analysis reveals rapid population shift among Pleistocene cave bears
...changes. The new work, reported by a collaborative group of researchers including Michael Hofreiter of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, appears in the February 20th issue of the journal Current Biology, published by Cell Press. To investigate the stability of anc...New test for most virulent HPV strains under study
...s likely would continue to be used in the under-30 group to catch the few infections that become problematic in this age group. Currently, there are not FDA-approved drugs to cure cervical pre-cancers and cancers caused by HPV, although centers such as MCG are evaluating potential therapies. Resulting c...NIH announces phase III clinical trial of creatine for Parkinson's disease
...m laboratory research to pilot studies in a select group of patients, to the definitive phase III trial of effectiveness in people with Parkinson’s disease. "This study is an example of the Institute's commitment to Parkinson's research," says NINDS director Story C. Landis, Ph.D. "We are trying to exp...Can engineered immune cells stop AIDS?
...to achieve the desired targeted delivery. With a group of USC biomedical engineering students and Caltech biologists, Wang is experimenting with CD20 as a target antigen for human B cells. His strategy, published in the August 1, 2006 issue of Proceedings of the National Academy of Sciences, targets the...Tiny clue reveals new path toward heart disease
...ire genome -- the body's genetic blueprint -- of a group of families in which at least two siblings had early onset coronary artery disease, looking for regions of "linkage" where DNA variations appeared to be inherited along with the disease. They found just such a region: a small section of the long arm ...A steady, high-fat diet is bad, but the news gets worse
...he stress responses of two groups of students: one group consumed a fast-food breakfast from McDonald’s, the other ate dry cereal with skim milk, cereal bars and non-fat yogurt. "What’s really shocking is that this is just one meal," says Dr Tavis Campbell, a specialist in behavioural medicine and seni...Experimental vaccine given during pregnancy reduces stillbirths from common virus
...igs not receiving the vaccine. The vaccinated group (10 litters) produced 28 live pups and 4 dead pups—a mortality rate of 13 percent. The control group (8 litters), which received a vaccine for the flu, produced 9 live pups and 12 dead pups—a mortality...Stanford scientists make major breakthrough in regenerative medicine
...pecifically, sea squirts, like humans, belong to a group of animals called chordates (organisms with some l... a landmark in regenerative medicine; the Stanford group has accomplished the biological equivalent of turning a sow’s ear into a silk purse and back again."......trands is altered upon exposure to UV light. Now a group of researchers at Duke University have developed a method to measure changes in the mechanical properties of DNA upon irradiation with UV light. Piotr Marszalek and his colleagues have conducted single-molecule force spectroscopy measurements on vir...Bumblebee house warming -- it takes a village
...ng workers and lowering the nest temperature. One group of bees was consistently involved incubating across a range of temperatures. In a second experiment, the researchers removed the most active incubating workers. When this happened a colony's remaining incubators responded within 24 hours by increas...Key found to kill cystic fibrosis superbug
...The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia. These investigators, under the leadership of Dr. Miguel Valvano, Department of Microbiology and Immunology, have had their research published in the...Natural polyester makes new sutures stronger, safer
...ocused their "biopolymer engineering" efforts on a group of genes that code for enzymes in a pathway that produces polyesters. Those polyesters can be broken down into metabolites naturally produced by humans, so they cause no harm when absorbed. Once the genes were identified, they could be transferred...A tiny whitefly is responsible for spreading a group of plant viruses that cause devastating disease on... exclusive insect vector (transmitter) for a large group of emerging plant viruses that infect several hundred plant species worldwide. "Once considered an o...