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Tag: "greatly" at biology news

Dysentery uses 'sword and shield' to cause infection

... the immune system. Dr Tang adds: "This discovery greatly expands our understanding of how bacteria are sometimes able to evolve although it is unlikely to result in new treatments or vaccines for dysentery. In this case, the dysentery bacteria has evolved into a highly effective and dangerous infection." ...

Novel technology detects human DNA mutations

...P segment between two oligonucleotide sequences to greatly increase detection specificity and sensitivity. One segment identifies any mutations in the DNA and the probe, a highly sensitive gold nanoparticle, creates a strong signal accurately indicating the presence of a specific target SNP. Proof of princip...

Controversial drug shown to act on brain protein to cut alcohol use

...held alcohol fortwo weeks, which normally leads to greatly increased drinking when whenalcohol is again available. When they administered Ibogaine, they foundthat the heightened craving and consumption was significantly reduced."The discovery that Ibogaine reduced binge drinking after a period ofabstinence w...

Anti-bacterial additive widespread in U.S. waterways

...findings suggestthat triclocarban contamination is greatly underreported. The study ispublished in the current online edition of Environmental Science &Technology, a peer-reviewed journal of the American Chemical Society. "We'vebeen using triclocarban for almost half a century at rates approaching1 mill...

A much-needed shot in the arm for HIV vaccine development

...aid Anthony S. Fauci. "By workingtogether, we will greatly accelerate progress toward the critical goalof developing a safe and effective HIV vaccine to help curb the globalHIV/AIDS pandemic.""Being from the continent worst hit by the HIV/AIDS epidemic that hasclaimed more than twenty million lives and wiped...

New Technique for Tracking Gene Regulators

...Brookhaven National Laboratory. The techniquecould greatly speed the process of unraveling the role these proteinsplay in turning on and off the genes that establish the very identityof cells ?be they brain cells, liver, or blood ?as well as what mightgo awry in certain conditions like cancer. TheBrookhaven...

Mitochondrial DNA mutations play significant role in prostate cancer

...mitochondria. Hence, the deleteriousmtDNA mutation greatly enhanced prostate cancer growth.Since mitochondria make oxygen radicals as a by-product of makingenergy, and oxygen radicals can stimulate cell growth, the researchersthen tested the tumors for oxygen radical production. The tumors withthe mutant mtD...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...childhood live longer, but life expectancy remains greatly decreased. Although Pompe disease is a relatively rare disease, it is but one of a group of related "lysosomal storage diseases," which in total occur in about one in 5,000 births. The current study is part of a large, collaborative effort at Duke U...

Genetically modified natural killer immune cells attack, kill leukemia cells

...e triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cells. The researchers then genetically modified the growing NK cells so they carried on their surface an artificial receptor that made them particularly aggressi...

Researchers add new tool to tumor-treatment arsenal

...w, combined with possible severe side effects, has greatly limited their broader use." These factors, says Dr. Thomas, have probably contributed to recent reports of the under-dosing of patients and the failure to blunt the disease. When cancer cells are treated with a DNA-damaging agent, a cancer-suppress...

Devising Nano Vision for an Optical Microscope

...ngths of light in the visible part of the spectrum greatly exceed nanoscale dimensions. Consequently, the resolution of conventional light-based imaging methods is limited to about 200 nanometers—too large to resolve the details of nanotechnology, which, by definition, are no more than half that size. Howev...

New methods of gene delivery using lasers

...ve touched on this area, the St Andrews group have greatly simplified the technique by using an extremely simple and versatile miniature violet laser which is compatible with standard microscopes. The method is very powerful, and in contrast to other methods the team can select individual cells to be treated...

Protein offers way to stop microscopic parasites in their tracks

... be cut off at the back or they will jam the belt, greatly reducing the parasite's ability to move and thereby infect a host. A postdoctoral researcher in Sibley's lab, Fabien Brossier, Ph.D., decided to try to use the recently completed Toxoplasma genome to search for the protein that lets the parasite det...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...by an extremely sensitive detector. Each DNA piece greatly increases the sensitivity of the test and its potential to tell doctors a patient carries the ADDLs. According to the researchers, BCA is about 1 million times more sensitive than the next best thing ?standard enzyme-linked immunoassays (ELISAs). EL...

Biodiversity hotspots identify conservation priorities

...ecently in 2000. "This new analysis has benefited greatly from increased collaboration among countries and organizations, as well as from scientists' ever-increasing knowledge of species and their habitats," said Gustavo A.B. da Fonseca, executive vice president of CI. Two factors determine which areas qua...

GeneNotes - A novel information management software for biologists

...of more intelligent human-computer interfaces that greatly shorten the cycle of biology research. ...

Strongest proof yet found for prion hypothesis

...g a much-needed blood test for prions, which would greatly improve current surveillance techniques for mad cow disease and its human form, new-variant Creutzfeldt-Jakob Syndrome. ...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...e triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cells. The researchers then genetically modified the growing NK cells so they carried on their surface an artificial receptor that made them particularly aggressi...

Used in a new way, RNA interference permanently silences key breast cancer gene

...tically reduced in the STAT3 knockdown cells, thus greatly reducing the ability of these cancer cells to invade normal tissues like the lung. "Somehow STAT3 is controlling TWIST expression, and this is important to know with regards to activated STAT3 and its involvement in cancer metastasis," Arlinghaus say...

Shift of weather patterns necessitates rethinking of reforestation methods

Forest landowners can greatly increase the survival rate of pine tree seedlings by changing when and how they plant, according to research conducted here. "There's been too many (reforestation) failures over the last decade or so," said Dr. Eric Taylor, Texas Cooperative Extensi...

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