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A gene's first 'kiss' sets off that affair known as puberty

...d when the brain activates this process has been a great mystery. An appreciation of puberty's deep-seated neurobiological mechanisms could, for instance, help prevent precocious or delayed puberty from occurring in some children," noted the study's lead author, Tony Plant, Ph.D., a professor in the depart...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

... a white-hot fieldof research that has attracted a great deal of interest in thepharmaceutical industry. This picture has now been further reinforcedby new findings­ - the result of multidisciplinary and internationalcollaboration involving world experts on the interferon system,immunology, and the disease...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...imic the environment when life began. "There is a great deal of interest in the microbes of the Earth's crust because the strategies by which they survive may be similar to the earliest strategies of life on Earth, and perhaps also on other planetary bodies," said Rachel M. Haymon, UCSB professor of geolo...

UW's Rosetta software to unlock secrets of many human proteins

...are termedthe "Rosetta score." The program tries a great many conformations andreturns those with the lowest Rosetta scores; these conformations comeclosest to the actual shape of the protein.Rosetta was developed in the laboratory of UW Professor David Baker bya large team of scientists and students. Form...

Researchers find how protein allows insects to detect and respond to pheromones

...are termedthe "Rosetta score." The program tries a great many conformations andreturns those with the lowest Rosetta scores; these conformations comeclosest to the actual shape of the protein.Rosetta was developed in the laboratory of UW Professor David Baker bya large team of scientists and students. Form...

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

...r, Gene ExpressionMarketing at Affymetrix. "We had great success with this program lastyear. By providing the plant and animal community groups with a single,standardized platform for gene expression research, they can easilycompare results, build reliable databases and move science forward morequickly."Af...

Computers to be used to find blueprint for new influenza drug

...t. Using computer modelling in this way can be of great assistance in drug design. Normally drugs are produced by trial and error in a process that can take many years. Professor Williams and his colleague Dr Gus Ruggiero will use part of the grant from the Biotechnology and Biological Sciences Research ...

Study Links Ebola Outbreaks To Animal Carcasses

...is research proves that hunting and consumption of great apes represent a serious health risk for people in Central Africa, and a risk that can be avoided," said Dr. William Karesh, field veterinarian for the Wildlife Conservation Society and a co-author on the paper. "What we need now is improved awarenes...

“Nano-scissors?laser shows precise surgical capability

...section a singleaxon (the "arms" of a neuron) with great precision : Anultra-short pulse laser that can perform extremely precise surgery ontiny roundworms may be the key to understanding nerve regeneration andis an important step toward treatment of human neurological disease,according to research publis...

The secret lives of whales

...tic, where only 10% of historic populations of the great whales are estimated to still survive, Smith specu...veloped at Cornell, Clark is investigating how the great whales move in acoustic herds, communicating over 1000’s of square miles of ocean by using sound. “T...

An HIV Protein Plays a Surprising Role in Gene Activation

...es to co-opting their host's cellular resources. A great deal of human complexity stems from the vast repertoire of proteins and mechanisms dedicated to the business of regulating gene expression, and retroviruses like HIV have evolved myriad ways of redirecting that machinery to their own benefit. Humans...

Critical role in programmed cell death identified

...unifies two different hypothesis and makes worms a great model to analyze how cell death is induced, " Conradt said. Mitochondria are dynamic structures, constantly changing shape, budding and fusing. In cells instructed to die, the mitochondria tend to become smaller or fragment, but whether this fragmen...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...treatment can backfire. “Levodopa generally works great for several years, but then it actually starts creating movement problems,?Mandel said. “Our idea is that instead of taking pills that create detrimental fluctuations of L-dopa levels, a continuous, therapeutic dose would be better for you. As for e...

Jumping gene helps explain immune system's abilities

...," says Craig.But the a la carte approach provides great diversity from a limitednumber of choices, whether in the immune system or in a cafeteria. Forexample, at a cafeteria, one diner could have a meal of mashedpotatoes, broccoli and a pork chop, and another French fries, salad anda hamburger, and so on ...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

...," says Craig.But the a la carte approach provides great diversity from a limitednumber of choices, whether in the immune system or in a cafeteria. Forexample, at a cafeteria, one diner could have a meal of mashedpotatoes, broccoli and a pork chop, and another French fries, salad anda hamburger, and so on ...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

...," says Craig.But the a la carte approach provides great diversity from a limitednumber of choices, whether in the immune system or in a cafeteria. Forexample, at a cafeteria, one diner could have a meal of mashedpotatoes, broccoli and a pork chop, and another French fries, salad anda hamburger, and so on ...

Gene sequencing explains bioremediation 'bug'

...," says Craig.But the a la carte approach provides great diversity from a limitednumber of choices, whether in the immune system or in a cafeteria. Forexample, at a cafeteria, one diner could have a meal of mashedpotatoes, broccoli and a pork chop, and another French fries, salad anda hamburger, and so on ...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

..." said Akhremitchev. "And that is why it is such a great challenge. That's what we want to learn." ...

Tiny scaffolding allows stem cells to become working fat cells

...t in which a community of cells finds itself has a great deal of influence on the biology underway within those cells," Kniss said. "And that biology is always translated into changes in gene expression and assemblies of proteins." That is why the three-dimensional scaffolding for cell growth in the labora...

Boosting HIV screening can increase survival and is cost effective

...with those of our colleagues, firmly establish the great value of expanded screening." Paltiel and his team developed a mathematical model of HIV screening and treatment to predict the costs and benefits of HIV counseling, testing and referral. They found that routine, voluntary HIV screening every three ...

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