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Tag: "graft" at biology news

U-M scientist to talk about tissue engineering at AAAS

...moved from the jaw, that often means taking a bone graft from someplace like the hip. That approach has problems both for the wound at the donor site and for the site where it is implanted. In addition to discussing the sometimes-messy real world applications of tissue engineering, Krebsbach plans to talk...

Gene therapy converts dead bone graft to new, living tissue

...transform the dead bone of a transplanted skeletal graft into living tissue in an experiment involving mice...asily handled, and painted it directly onto a bone graft during surgery. Numerous tests in mice confirmed that the virus permeated the inflammatory tissue a...

Gene therapy promising for growing tooth-supporting bone

...uctive surgery today involves either taking a bone graft from the patient's chin or jaw, which leaves a second wound needing to heal, or using donated bone from a tissue bank, which yields unpredictable results. William Giannobile, professor of periodontics, prevention and geriatrics, led a team at the U-...

Monkeying around to improve organ transplantation

...ery prolonged ?80 days?and perhaps even indefinite graft survival in three long-surviving animals without administration of additional immunosuppressive agents. This study shows for the first time that anergic T cells generated ex vivo suppress renal allograft rejection in non-human primates. This may be a...

Simple sea sponge helps scientists understand tissue rejection

...ls known as gray cells migrate to and amass at the graft site, a clear suggestion that they are involved in non-self tissue recognition and rejection. Researchers believe that gray cells may be a primitive form of our immune system's human killer cells. Fernndez-Busquets has also been researching the role...

Nanotubes inspire new technique for healing broken bones

...largest scientific society. The success of a bone graft depends on the ability of the scaffold to assist t...cial bone materials, leading to a new type of bone graft for fractures that may also be important in the treatment of bone-thinning diseases such as osteopor...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

...2003, approximately 750,000 coronary artery bypass graft (CABG) surgeries were performed worldwide and approximately 1.8 million balloon angioplasty procedures were performed. While these interventional therapies are now the standard of care, there are still a significant number of people for whom these me...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

...in the transplanted heart tissue that indicate the graft is being rejected by the body's immune system. These procedures are costly, uncomfortable and must be repeated annually for a few years to monitor and treat any rejection. Biopsies also are problematic, according to Ho, because they do not look at t...

Cyclosporine inhibits hepatitis C virus in vitro

...to the accelerated rate of disease progression and graft failure after liver transplantation in HCV patients," the authors conclude, "it will be very important to determine the ideal immunosuppression regimen." ...

Sticky surfaces turn slippery with the flip of a molecular light switch

...ated, but so is the patented procedure required to graft spiropyran molecules to poly(ether sulfone). "We used a relatively simple two-step process that could be easily incorporated into a commercial manufacturing process," Belfort says. "The relative ease of this grafting and switching process suggests ma...

Finding paves way for better treatment of autoimmune disease

... cell therapy also resolved symptoms in a model of graft versus host disease, a problem for some bone marrow transplant patients when immune cells from the donor start attacking. This finding indicates a potential role for helping transplant patients keep new organs, the researchers say. Dr. Iwashima has...

Common cold virus leads to death in lung transplant patients

...ients, leading to progressive respiratory failure, graft dysfunction and death. The two were part of a grou...iratory infections, and two subsequently died with graft dysfunction." Dr. Kaiser noted that the persistent infection suggests that certain cases can act ...

Machine preservation may promote more organ sharing

...ction in the rates of viral infections and delayed graft function, which is the inability of the kidneys to start working on their own without dialysis. "The routine use of machine preservation for ECD kidneys may lower hospital costs by reducing complications," said Stratta. "In addition, it may promot...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...tient’s leg continues to be the most commonly used graft for coronary artery bypass grafting even though a ...tsburgh School of Medicine, developed its vascular graft by “bulk seeding,” or spraying, MDSCs inside a biodegradable porous, tubular polyester urethane scaf...

Research shows cord blood comparable to matched bone marrow

...n the body, it was associated with a lower risk of graft versus host disease, a potentially lethal complication, especially when HLA types are mismatched. Rates of leukemia relapse also are lower with mismatched umbilical cord blood transplants. This study also showed that in addition to having a good matc...

Research identifies protein that signals flowering in squash plants

...umpkin) stocks (the stock is the portion below the graft union containing the roots) grafted to non-induced...LD-grown C. moschata scions (the portion above the graft union). These experiments led to flowering of the C. moschata scions, indicating efficient transmiss...

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