Angelman syndrome deficits rescued in mice
...ouse model," he said. "We had no idea that we were going to rescue basically everything." Although impossible to apply the genetic engineering used in the current study to correct these deficits in mice to humans, Weeber thinks that the findings may point to new therapeutic targets for the disorder. ...Yale biologists 'trick' viruses into extinction
...ording to a report in Ecology Letters. To avoid going extinct a population must not only survive, but also reproduce. Paul Turner , associate professor of ecology and evolutionary biology at Yale, tested the practicality of luring a virus population into the wrong cells within the human body, thus pr...Scientists find potential 'off-switch' for HIV virus
...me viruses will escape because they have hidden by going dormant. Eventually, these dormant viruses wake up and the infection returns, so it makes sense to try to keep the virus asleep if possible." HIV weakens the body's immune system by invading CD4+ T cells, which in essence serve as the metaphorical...Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight
...avez. "We realized there was something interesting going on with these animals, so we started watching their behavior at night and during the day." During continuous monitoring of temperature and motor activity, the researchers realized that the mice without the EP3 receptors were more active during the...Failure to meet United Nations sanitation target could affect millions of the world's poorest
...itation side, we're in big trouble. We're probably going to miss that goal by 500 million people." Sani...n water or in having sanitation facilities, you're going to be going for the water," she said. "It's a rational prioritization in the short term. Everyone ca...Proteins important in Alzheimer's, Parkinson's disease travel in the slow lane
...ergy transporting proteins separately when they’re going to the same place anyway, like car pooling" speculates Roy. "Our study reveals novel aspects of axonal transport of an important class of proteins, namely the slow component-b proteins, and also opens up new avenues for investigating axonal trans...Global 'sunscreen' has likely thinned, report NASA scientists
...gh the atmosphere and warm Earth's surface, you're going to have an effect on climate and temperature," said lead author Michael Mishchenko of NASA's Goddard Institute for Space Studies (GISS), New York. "Knowing what aerosols are doing globally gives us an important missing piece of the big picture of the...Sunshine pill for prostate cancer in 2009
... develop advanced disease. In fact death rates are going down, which means that the market for this drug is probably pretty static.' James also points out that it is far from certain that the Phase III trials will repeat the success of early trials. 'The phase II trial used a less than optimal taxoter...Custom-made cancer cell attacks
...ion. ''There's a lot of deforestation certainly going to take place in tropical regions, because those countries are going to develop biofuel businesses,'' he said. ''Already in Malaysia, Indonesia, the Philippines, the acr...Cellulosic ethanol: Fuel of the future?
...ion. ''There's a lot of deforestation certainly going to take place in tropical regions, because those countries are going to develop biofuel businesses,'' he said. ''Already in Malaysia, Indonesia, the Philippines, the acr...Researchers hot on the trail of brain cell degeneration
... Cooperation between biocentres gets research going The teams' study is a perfect example of the cooperation between biocentres in Finland (Biocenter Finland) and international networking. The research was funded mainly by the Academy of Finland and the European Union. The two research teams are p...New cigarette designs don't offer lower predicted cancer risks
...ohol by drinking 10 beers a day, but says they are going to cut down to 9." Such findings could lead to tightened restrictions on how tobacco companies market their products. Legislation is now being considered in Congress on whether and how the U.S. Food and Drug Administration should be allowed to reg...Mosquito genes explain response to climate change
...th is often the primary cue that organisms use for going dormant, and although human beings are not as stro...ly, but rather they are flowering, reproducing and going dormant at different times of the year than they used to. Many species will be unable to change qui...Neural bottleneck found that thwarts multi-tasking
...e possible to look to the sort of tasks people are going to have to do in a very complex environment, such as flying a plane, and find out under what circumstances these tasks may be less vulnerable to dual-task interference," Dux added. For the record, neither Marois nor Dux use their cell phones while...Study of planarians offers insight into germ cell development
...to get at the mechanisms that tell a cell: ‘You’re going to be a germ cell.?" S. mediterranea also has t...ple organism that also uses inductive signaling is going to help us tease apart the more conserved mechanisms (of germ cell development and maintenance)," Ne...New hereditary breast cancer gene discovered
...Plastic Surgery Clinic. The scientists are now going to perform various experiments to chart the mechanism of how TWIST1 increases the risk of breast cancer. Studies are also under way to find out what proportion of cases of hereditary breast cancer are caused by mutations in the TWIST1 gene. ...Short chromosomes put cancer cells in forced rest
... cancer free. "We were confused as to what was going on; we thought for sure that blocking the cells?ability to commit suicide would lead to the cancer’s returning," says Greider. A closer look showed microtumors in the mice’s lymph nodes that had begun the road to cancer, but stopped, falling instead ...Fish can determine their social rank by observation alone, study finds
...dvantageous for a male to know who the new boss is going to be and who his weakest rivals are. Our experiment shows that male cichlids can actually figure out their odds of success by observation alone. From an evolutionary standpoint, transitive inference saves them valuable time and energy." The resul...Syphilis rate on rise in US gay, bisexual men
...ool of Medicine, said rates among gay men could be going up for several reasons, including illicit drug use and "safe-sex fatigue." In addition, he said, prevention messages might have been "drowned out" by talk about how medications are doing a great job of keeping AIDS patients alive. "We’ve been sedu......-value plants, like natural forests. "We're not going to eradicate the adelgid," Costa says. "The best-case scenario for an insect-killing fungi is you inoculate the environment and get disease outbreaks to start cycling. The idea is to reduce the pest population to a level that is manageable, allowing ...