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St. Jude study solves mystery of mammalian ears

...explain the mechanics of hearing and what might be going wrong in some forms of deafness,” said Jian Zuo, Ph.D., the paper’s senior author and associate member of the St. Jude Department of Developmental Neurobiology. “There are a variety of causes for hearing loss, including side effects of chemotherapy f...

Art and music for the birds

...“I’m a Cuckoo” by Belle and Sebastian. “If we’re going to give birds music, we might as well give them what we consider to be our masterpieces. But the only gauge humans have on what’s good music is our own interest,” says the Rutgers-Camden artist. “Of course, we may find that birds have their own crite...

Modeling the restless brain

...ernal stimulus, there are very important processes going on in the brain which affect the stimulus-responses that the brain will produce. We believe that ongoing spontaneous activity should be studied in itself. Other researchers consider this to be unimportant 'noise' that should be filtered out." Hon...

Simulations unravel outer membrane transport mechanism

...he interaction of proteins,” he said. “And this is going in the direction of what’s called systems biology. This is essential because none of these proteins actually works alone. Each works in concert with many other things.” Tajkhorshid is also a professor of pharmacology in the College of Medicine and...

Studies to find better ways to preserve human eggs, ovarian tissue under way

... right now the standard of care for people who are going through cancer therapy is to use egg donors later on,” says Dr. Adelina M. Emmi, reproductive endocrinologist and medical director of MCG Reproductive Laboratories of Augusta. Treatment for leukemia and cervical, ovarian, breast or other cancers o...

Breakthrough developments in rheumatoid arthritis reported

...“This will help us in figuring out what exactly is going on in this illness,” he said. “It’s pretty exciting.” Early on in the rheumatoid arthritis research game, when HLA popped out as a major genetic player in the condition in the 1980s, Dr. Gregersen discovered that there was a shared bit of DNA th...

Migration alert -- How tumor cells home in on the lymphatic system

... drain fluid, there will always be slow fluid flow going away from the tumor into the lymphatic vessel. This slow flow biases the concentration distribution of this molecule towards the lymphatic, and the tumor cell follows it, like the proverbial carrot on a stick. Near the vessel, concentrations of the s...

Researchers examine carbon capture and storage to combat global warming

... ''People think, it would have been sort of sad going through all this trouble,'' said Tony Kovscek, ass...on sequestration. ''Geological sequestration is going to be one of a family of solutions for addressing the greenhouse gas issue,'' said Zoback. Energy...

Research finds that circadian rhythms dominate all life functions

...rmance; each musician continues to play, gradually going out of key with the others," said Ptitsyn. That is one likely reason why researchers previously missed the impact of circadian rhythm on all genes. Depending upon environmental factors, groups of genes can function in a synchronized manner, shiftin...

Runners -- Let thirst be your guide

...ut for an hour or two of strenuous exercise is not going to be at risk for this,” he adds. Verbalis also...ly including re-hydrating by drinking, they’re not going to be at risk of either dehydration from excessive sweat losses or EAH from excessive fluid ingestio...

Mutating the entire genome

...though probably at least half of the ‘junk’ DNA is going to end up having a pretty important function,” Capecchi says. Capecchi is known for developing gene targeting, in which mice are bred with a gene disabled or “knocked out” to see what goes wrong, thus revealing the gene’s normal function and how ...

Modified mushrooms may yield human drugs

...onomical, safe, and fast. We believe mushrooms are going to be the platform of the future." To create transgenic mushrooms, researchers attached a gene that confers resistance to hygromycin, an antibiotic, to circular pieces of bacterial DNA called plasmids, which have the ability to multiply within a b...

Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

...rch, Urban cautioned: "It doesn’t prove that we’re going to be able to do this in people — it’s just the first step up the rung of the ladder." The lead author of the paper, UTMB professor of internal medicine/endocrinology Larry Denner, said that by working with adult stem cells rather than embryonic s...

Treating HIV in war zones -- Public health emergencies need rapid advice from WHO

...HO terms", an even quicker time frame is sometimes going to be needed. Citation: Schünemann HJ, Hill SR, Kakad M, Vist GE, Bellamy R, et al. (2007) Transparent development of the WHO Rapid Advice Guidelines. PLoS Med 4(5): e119. IN YOUR ARTICLE, PLEASE LINK TO THIS URL, WHICH WILL PROVIDE ACCESS TO T...

Mice with a migraine show signs of brain damage

...der to treat a migraine, you treat the pain. We’re going beyond that. Migraines could be dangerous. The focus should be on prevention,?said Nedergaard, who notes that by the time a person feels pain or notices a visual disturbance, the changes to the brain are already well underway. To make the finding,...

Technique monitors thousands of molecules simultaneously

...olution destroys the reagent made, keeping it from going to another electrode. This was done for the genera...hat were turned on. To keep the palladium(II) from going to a neighboring electrode a second reagent was added to the solution above the chip that destroyed ...

'Insulator' helps silence genes in dormant herpes virus

...anism used to keep this small region of the genome going while nearby genes remain quiescent. Now, scientists at The Wistar Institute have discovered a molecular mechanism that keeps HSV-1 activation restricted to a single gene for months or even years. The researchers have identified an "insulator" ?a ...

A frown or a smile? Children with autism can't discern

...tterns of behavior. “They don’t pick up what’s going on ?they miss the nuances, the body language and facial expressions and sometimes miss the big picture and instead focus on minor, less socially relevant details,?Davies said. “That, in turn, affects interpersonal bonds.? ...

UQ research heralds vaccine technology breakthrough

...ll kinds of angst because their young children are going into hospital with very worrying symptoms and it w...pertise was a coup for the project. "If anyone's going to get the (vaccine) it's going to be Scott," Professor Tindle said. ...

Molecule that destroys bone also protects it, new research shows

...edicted these mice without the IL-17 receptor were going to be protected from periodontal bone loss, just like they’re protected from arthritic bone loss," Gaffen said. "In fact, we got the opposite result. The mice without IL-17 were much more susceptible to bone loss caused by periodontal disease, compa...

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