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Tag: "glycosylation" at biology news

Integration of Agilent's MS technology, Proteome Systems' software to help scientists in proteomics research

...r automated glycan analysis. "Analysis of protein glycosylation is a demanding task that has often been reserved for specialized laboratories," said Nicolle Packer, executive vice president and head of glycoproteomics of Proteome Systems. "The combination of Agilent's robust, sensitive MS technology with our cutt...

GlycoFi announces the first production of antibodies with human glycosylation in yeast

... the GlycoFi yeast remained identical and only the glycosylation structures of each antibody was altered. Compariso...d that antibody binding varied with changes in the glycosylation structure. Moreover certain antibody glycoforms showed significantly increased antibody mediated cel...

Report calls for improved monoclonal antibodies against solid tumors

...ize, charge, and valence; constant region type and glycosylation pattern; presence or absence of a radioisotope or a toxic moiety; dose, route, and schedule of administration; and use of a traditional or of a pre-targeting strategy.?They conclude the framework they offer “should facilitate critical choices among a...

GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

...demonstrated in vivo. "Re-engineering the yeast glycosylation system to fully replicate the full repertoire of human glycosylation reactions has been a challenging six year effort that many doubted could be accomplished," said Till...

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