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Tag: "glioblastoma" at biology news

'Smart drug' targets deadly brain cancer

...kind of tumor arising from brain tissue of adults, glioblastoma mutiforme. Current treatment outcomes for this typ...World Health Organization categorizes fast-growing glioblastoma multiforme as a grade IV cancer. Significance of the Mayo Clinic/NCCTG Research This discouraging ...

UCLA discovery will aid in treatment of patients with a deadly brain cancer

... critical." Between 8,000 and 10,000 new cases of glioblastoma will be diagnosed in Americans this year. Average ...f the protein and speed cancer growth. A subset of glioblastoma patients responded to Tarceva and Iressa, but it was not clear what characteristics made them respon...

Preclinical study of a new brain tumor therapy

... PLoS Medicine, has applied the approach to combat glioblastoma multiforme (GBM). This is the most aggressive form...n as epidermal growth factor receptors (EGFR). The glioblastoma cells overexpress EGFR (that is, in comparison with normal brain cells, they have many more of these...

Radiotherapy advance points way to noninvasive brain cancer treatment

...r cell nuclei, using four different kinds of human glioblastoma cells in culture. De Stasio developed and oversees the X-ray PhotoElectron Emission spectroMicroscopy (X-PEEM) program at UW Madison's SRC, where she also serves as interim scientific director. The technology necessary for eventual treatment would ...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

...ne strain of the measles virus to attack recurrent glioblastoma multiforme, a largely untreatable brain tumor. Th...lanis, M.D., oncologist and lead researcher on the glioblastoma multiforme project in the measles virus investigation. "We have shown in the laboratory and in seve...

Scientist works to improve treatment for brain tumors

....D., Ph.D., pioneered a method to destroy cells of glioblastoma multiforme (GBM) with less damage to healthy cells...s development was based on Debinski's finding that glioblastoma cells over-express large amounts of a receptor for interleukin 13 (IL13), a protein that regulates t...

Killing brain tumors from within: A 'Trojan horse' approach

...ypical of certain types of cancer cells, including glioblastoma multiforme (GBM), the most lethal form of brain cancer. The nucleic acid-EFG molecule acts as a "guided missile," explained Prof. Levitzki, which, when injected into the blood stream, is avidly gobbled up by the multiple EGF receptors on the canc...

Cancer stem cells linked to radiation resistance

...aid. In the current study, the researchers used glioblastoma tissue removed from patients during neurosurgery a...atory. For the second model, they transplanted the glioblastoma tissue into the frontal lobes of the brains of mice. The researchers first measured the number of...

Natural protein stops deadly human brain cancer in mice

...r ability to divide. First they pretreated human glioblastoma cells with bone morphogenic protein 4 (BMP4), then... "beads" directly into mouse brains with implanted glioblastoma cells. Mice that got empty beads developed large malignant tumors and died. Mice with BMP4 beads sur...

Investigating the measles virus as a tool to kill multiple myeloma

...ing tested today in several tumor types, including glioblastoma multiforme (a brain tumor), recurrent ovarian canc... and potentially even more potent viral doses. The glioblastoma multiforme trial, which opened in the fall, is testing the safety of another strain of the measles v...

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