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Tag: "gland" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...satile fashion. With each secretion, the pituitary gland is stimulated to secrete its own messengers, lutenizing hormone (LH) and follicle-stimulating hormone (FSH), directly into the circulation. In turn, these rising levels of LH and FSH cause the testes and ovaries to produce the sex hormones testostero...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...d, the more likely it is that the patient's thymus gland can act as an efficient factory where stem cells become T cells. The thymus is an immune system organ behind the breastbone that processes immature "precursor" immune cells into specialized T cells. T lymphocytes are specialized immune cells carryin...

Effective Cancer Treatments Follow The Clock

..., cardiac output, oxygen consumption and endocrine gland secretion. In their experiments, the researchers measured the animals' body weight as an indicator of response to the anti-cancer drug. They discovered that Clock-mutant and Bmal1-knockout mice showed high sensitivity to the drug at any time it was ...

Compounds in plastic packaging act as environmental estrogens altering breast genes

... could alter the genomic signatures of the mammary gland during critical stages of development." BPA (bisph...sure modified the genomic signature of the mammary gland primarily at 21 days of age and had less effect later," Moral said. Future studies are needed to de...

Study: Well-known protein helps stem cells become secretory cells

...lates secretion levels in the fruit fly's salivary gland and its skin-like outer layer. Described in the M...s leading to secretion in the fruit fly's salivary gland and epidermis, its skin-like outer layer. CrebA, or a closely related human gene, might play the sa...

New tool reveals secrets of migrating cells

...id of her studies in the thymus, the immune system gland that weans baby T cells into activated helper, or CD4, cells and killer, or CD8, cells primed for combat with viral invaders. "We were surprised by how rapidly and directly the cells move to their final destination." The technique could allow resear...

Hormones and growth: The control of body size and developmental growth rate in fruit flies

...one from an endocrine organ called the prothoracic gland triggers larval molting and, ultimately, metamorph...al. In contrast, inhibiting Ras in the prothoracic gland prevented ecdysone release and delayed development, creating flies that are much larger than normal....

Gene for immune deficiency syndromes found

...o autoimmunity, particularly affecting the thyroid gland and resulting in thyroid hormone insufficiency. Finally, people with CVID are susceptible to B-cell lymphomas. The researchers, led by Raif Geha, MD, and Emanuela Castigli, PhD, in the Division of Immunology at Children's Hospital Boston, found muta...

Protein amplification in melanoma is possible drug target

...o autoimmunity, particularly affecting the thyroid gland and resulting in thyroid hormone insufficiency. Finally, people with CVID are susceptible to B-cell lymphomas. The researchers, led by Raif Geha, MD, and Emanuela Castigli, PhD, in the Division of Immunology at Children's Hospital Boston, found muta...

Scientists find a maturity gene in fly

...roid hormone named ecdysone, which is emitted by a gland as the larval stages end. When the gene was disabled, the fly larvae started metamorphosis but died within 12 hours. In some, their heads failed to emerge from their bodies. "How does an animal know when it is ready to mature ?what determines that t...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

...roid hormone named ecdysone, which is emitted by a gland as the larval stages end. When the gene was disabled, the fly larvae started metamorphosis but died within 12 hours. In some, their heads failed to emerge from their bodies. "How does an animal know when it is ready to mature ?what determines that t...

Researchers find gland that tells fruit flies when to stop growing

...ly's size as it grows during the larval stage. The gland then sends hormonal signals when it senses the fly... false signals about a fly's weight. Enlarging the gland by increasing insulin signaling triggered metamorphosis at smaller sizes than usual. Suppressing the...

Building a better mouse model of lung cancer: FHIT counts

...el growth in the eyes, brain, spinal cord, adrenal gland and other parts of the body. The scientists exposed mice deficient in both genes to a second carcinogen, DMN, which is also found in smoke but also in beer, fish meal and some preserved meats. They discovered that when the VHL gene was missing as we...

Male elephants woo females with precise chemistry

...ring musth by male Asian elephants from a temporal gland located between the eye and ear, comes in two forms, each representing one half of the enantiomer pair and identified as either "plus" or "minus." The OHSU and New Zealand team showed that the enantiomers of frontalin are released in the elephants i...

Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer

...ts the robotic instruments to dissect the prostate gland and surrounding tissue. Unlike standard laparoscopic approaches that require counter-intuitive movements by surgeons (whereby the surgeon must move his hand to the left in order to move the mechanical device to the rig...

Scientists learn to predict protein-stabilizing ability of small molecules

...ts the robotic instruments to dissect the prostate gland and surrounding tissue. Unlike standard laparoscopic approaches that require counter-intuitive movements by surgeons (whereby the surgeon must move his hand to the left in order to move the mechanical device to the rig...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

... About Prostate Cancer The prostate is a small gland about the size and shape of a walnut situated just...th small changes in size and shape of the prostate gland cells which can develop into an uncontrolled growth of cells. Prostate cancer predominantly affect...

Researchers use 'trickery' to create immune response against melanoma

... About Prostate Cancer The prostate is a small gland about the size and shape of a walnut situated just...th small changes in size and shape of the prostate gland cells which can develop into an uncontrolled growth of cells. Prostate cancer predominantly affect...

Scientists discover basic defect in cystic fibrosis airway glands

... that cystic fibrosis airway glands have defective gland secretion in response to certain drugs," explains ...rovide evidence that the defective cystic fibrosis gland secretion is not due to a potentially excessive fluid reabsorption pathway within glands but is due ...

New brain hormone puts brakes on reproduction

...sing hormone (GnRH). GnRH stimulates the pituitary gland to activate the reproductive system, whereas GnIH appears to reduce the effects of GnRH stimulation. Researchers have long sought inhibitors of pituitary gonadotropins, but many had come to believe that such a direct inhibitor was unlikely in the co...

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