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Tag: "gives" at biology news

Scientists pinpoint inflammation gene

...ro explained, "Basically, this rarer form of SEPS1 gives you a lazy cellular 'garbage truck' that doesn't properly do its job of clearing out the misfolded proteins that lead to inflammation." As further confirmation of their study results with the Wisconsin population, the researchers looked to see if t...

Mining biotech's data mother lode

... there is again not a trivial task. Dr Schroeder gives an example. "The medical faculty here were studying pancreatic tumours. They found 1,000 genes over expressing. Using our software they were able to find, among others, three protein interactions that were particularly relevant. Using our literature ...

Yale participates in global human genome initiative

...ent of cancer. "Participation in this consortium gives us a cutting-edge technology to systematically screen the human genome using cell-based models of human diseases," said Kevin P. White , associate professor of genetics , ecology and evolutionary biology and the lead investigator for Yale. The ...

Free-energy theory borne out in large-scale protein folding

...id sequence in a protein. But knowing the sequence gives no clue to the protein's function, because function is inextricably tied to shape, and every protein self-assembles into its characteristic shape within seconds of being created. "The folded, functional form of the protein is what really matters, an...

Changes to embryos can elicit change in adult fish

...ined Streelman. "When the in-lever is long, this gives the jaw a high mechanical advantage and the jaw can produce more force for biting. When the out-lever is long, that results in a lower mechanical advantage and a better design for suction-feeding. This negative correlation is produced by genetic inte...

How E. coli bacterium generates simplicity from complexity

... only six distinct functional states. "This study gives a systems biology view of how a phenotype, or a 'network state' advantageous to a microorganism is comprised of a tiny subset of a much larger universe of possibilities as provided for in the genome," said Palsson. "On a high level we can say that E....

UCLA discovery will aid in treatment of patients with a deadly brain cancer

...e possible to induce long-term disease suppression gives us reason for hope." The study, Mischel said, also may have important implications in other cancers. "Many cancers have a similar combination of a mutant cancer-causing protein and either the expression or loss of the PTEN protein," Mischel said. ...

Worms know bad food when they smell it

...umans, Bargmann said. "If you eat something and it gives you food poisoning ?especially if it's a flavor that you haven't experienced before, and especially if it's associated with vomiting, you form a very robust memory of that flavor and won't eat food with that flavor in the future. The smell elicits an...

New methods offer insight into regulatory DNA

...detect rare variations. However, our pilot project gives us greater confidence to take on a genome-wide survey of gene activity." A global map of sequence variation and gene activity will be an important tool in the interpretation of variation and disease. Such genome-wide association studies will be able...

Technique offers new view of dynamic biological landscape

...d ask about all the processes that it affects. "It gives you a less hypothesis-biased, more objective way of looking at the structure of biological systems," Weissman said. In future studies, Weissman and his colleagues plan to develop better quantitative measures of the effects of epistatic interactions...

Mouse study: New muscle-building agent beats all previous ones

... of myostatin, known as ACVR2B, is very potent and gives very dramatic effects in the mice," says Se-Jin Lee, M.D., Ph.D., a professor of molecular biology and genetics in Johns Hopkins' Institute for Basic Biomedical Sciences. "Its effects were larger and faster than we've seen with any other agent, and t...

Access to existing medical treatments could save more lives than spending to improve the treatments

...blic health physician. "For every dollar Congress gives the National Institutes of Health to develop blockbuster treatments, it spends only one penny to ensure that Americans actually receive them," said Steven H. Woolf, M.D., professor and director of research in VCU's Department of Family Medicine and a...

Engineers discover why toucan beaks are models of lightweight strength

...e result is a solid "foam" of air-tight cells that gives the beak additional rigidity. "The beak is mostly air," said Meyers. "While the inner part of human bone also contains cancellous bone, we don't have the foam interconnections, which produce a much stronger structure with very little additional weig...

HIV accessory protein disables host immunity via receptor-protein intermediary

...y disorders," suggests Weiner. "This research also gives us a new way to think about the relationship between immune activation and sepsis, and it may have implications ultimately for our understanding of novel approaches to prevent sepsis." ...

Free HIV tests cheaper than charging when goal is preventing AIDS

...ents HIV transmission, Thielman said. Testing also gives people access to services such as antiretroviral therapy, treatment for sexually-transmitted diseases and prevention of mother-to-child HIV transmission. ...

New male contraceptive clears hurdle

...hough. This new procedure could be the answer that gives men the decisive control we lack with current contraceptives." In the RISUG study, doctors inject a gel into the tube that sperm travel through after they are produced (known as the vas deferens). The gel then disables the sperm as they swim by. In ...

Living taste cells produced outside the body

...y lose weight and become malnourished. This system gives us a way to test for drugs that can promote recovery." The findings are reported in an online issue of Chemical Senses. Taste receptor cells are located in taste buds on the tongue and in the throat. These cells contain the receptors that detect ta...

Sweetgum tree could help lessen shortage of bird flu drug

... most abundant plant source, until now. "Our work gives the hearty sweetgum tree another purpose, one that may help to alleviate the worldwide shortage of shikimic acid," says study leader Thomas Poon, Ph.D., a professor of chemistry from the W.M. Keck Science Center at The Claremont Colleges in Claremont...

MIT chemist discovers secret behind nature's medicines

...ant beauty in this simplicity," and it may be what gives other enzymes the prowess required for making other medicinally valuable halogenated natural products, too. ...

Researchers get neurons and silicon talking

...Europe should be very proud of these resources. It gives us access to equipment and expertise that would be very hard to replicate elsewhere." ...

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