NIH Calls on Scientists to Speed Public Release of Research Publications
...om the publishing peer review process. The policy gives authors the flexibility to designate a specific time frame for public release ?ranging from immediate public access after final publication to a 12 month delay ?when they submit their manuscripts to NIH. Authors are strongly encouraged to exercise th...Key mechanism in genetic inheritance during cell division identified
...hly flexible cytoskeleton in biological cells that gives shape to cell walls and other structures, and controls the transportation of substances in and out of a cell. During cell division (mitosis), the microtubule fibers disassemble and reform into spindles across which duplicate sets of chromosomes line ...Glow-in-the-dark zebrafish at UH hold keys to biological clocks
...s of eggs being laid by each female per week. This gives the scientists a better chance of identifying mutant fish whose biological clocks run fast or slow, providing the ability to trace the specific genes that create the anomaly. Putting UH a bit ahead of other institutions engaged in this type of resear...Chemicals in tattoo inks need closer scrutiny
....cfsan.fda.gov/~dms/cos-204.html. This effectively gives a tattoo artist license to inject whatever he or she deems appropriate under the skin, according to the researchers. "Tattoos are no longer limited to the rough and rowdy," says Haley Finley-Jones, an undergraduate chemistry student and lead author ...Scientists identify genetic pathways essential to RNA interference
...on produced by RNAi is exquisitely specific, which gives it enormous potential for therapeutic application," says Gary Ruvkun, PhD, of the MGH Department of Molecular Biology, the study's senior author. "Imagine short, double-stranded RNA molecules that could be synthesized quickly and inexpensively to sil...Revolutionary nanotechnology illuminates brain cells at work
...e tone," Okumoto continued. "If you excite one, it gives a characteristic tone. If you bring the second fork close to the first one, it will also start to give you a tone even though they do not touch. This is resonance energy transfer." FRET is used to track the form of proteins that specifically bind me......ng local oncologists to serve as program directors gives the best results,?Ribeiro said. “The recruited oncologists serve as program directors, advocates of pediatric oncology units and coordinators of training for essential cancer care providers.?/p> The authors argue that even the low level of develo...Leprosy microbes lead scientists to immune discovery
...come much sicker," commented Bloom. "This research gives us insights about how the body develops protective immunity against bugs that invade our cells--or fails to. Now we know the players, and we would love to look at them in other diseases such as tuberculosis in the lungs and juvenile diabetes." Harva...Decoding the logic of olfaction
...atterns of activation in the cortex. "This finding gives a hint that there is some logic to the way that information is being mapped onto the cortex," said Buck. "We don't know what that logic is, but it seems as if it has something to do with the molecular features of the odorant." The researchers also f...Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer
...atterns of activation in the cortex. "This finding gives a hint that there is some logic to the way that information is being mapped onto the cortex," said Buck. "We don't know what that logic is, but it seems as if it has something to do with the molecular features of the odorant." The researchers also f...Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
...ulation of its signaling pathways". This research gives an insight into the complexity of signals that pass between vibrios and bivalve host cells and helps to explain how these processes develop in natural conditions and determine the fate of vibrios in the bivalve host. ...MUHC researchers make cancer target breakthrough
...orks in animal models is a major step forward, and gives us hope that this might also work in humans," explains Dr. Rozen. The research, funded by Strida Pharma--a McGill University spin-off company--also indicated that the antisense was particularly effective in reducing cancer tumors when administered i...Secret of smallpox's success may lead to bioterror cure
...ten projects funded under Project Bioshield, which gives federal agencies new tools to accelerate research ...rom Jacobs and his team's discovery of a gene that gives pox viruses uncanny ability to camouflage themselves from mammalian immune systems. The ability to s...Conserved amino acids play both structural and mechanistic roles in sandwich-like protein
...We believe that our discovery is novel and that it gives important new insight into the interplay between protein evolution, structure and folding." The researchers speculate that their conclusions about the azurin protein apply to most members of the sandwich-like protein family, but testing on other spe...... is unwound. This winding and unwinding of the DNA gives rise to torsional forces in the DNA, the magnitude of which increases as cell division progresses. These forces can delay the process of cell division and under certain conditions even stop it. Topoisomerase IB can reduce these torsional forces. The...Finding hidden invaders in a Hawaiian rain forest
...ve control strategies, and the Asner/Vitousek work gives us valuable insights about this problem. On a more practical level we need to know the distribution of invasives. Weeds are often difficult to find in dense, wet forest in Hawaii. This study has helped us with a particularly difficult-to-map species ...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
... combined with a randomly fluctuating environment, gives support to a current trend in fisheries toward adaptive management strategies. Fisheries harvest targets need to be flexible and precautionary. This result strengthens the scientific basis for these polices." The new study is believed to be the firs...Stem cell research - new cell lines
...earch offers a permanent answer to the problem. It gives the hope that we can produce a pure population of those cells in large numbers and transplant them into the patient." The researchers are currently in the discovery phase, where they are trying to characterise the three clonal lines they have develo......avior, found in birds but in no other vertebrates, gives them a vaguely comic appearance but is known to be critical for visual stabilization during body movement. What was not known was whether or not this means of avoiding "motion blur" was essential for high-quality vision in birds; many animals, includ......: "The rate at which mealworms were eaten by birds gives a measure of how effective each combination was at preventing detection by a predator. Combinations that gave a better disguise took longer to be seen, and it therefore took longer for the mealworms to be eaten." This research provides the first evi...