Unchecked DNA replication drives earliest steps toward cancer
...ibit many genetic mutations, sometimes dozens in a given tumor. An important scientific question, and one with significant clinical implications, has been what happens after the initial mutation that leads to dangerous later-stage cancers with multiple damaged genes. In a new study, researchers at The Wis...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
...inactive. In control experiments, the rodents were given rifampicin or ciprofloxin, and the scientists found that nearly all the wild-type E. coli cells had grown fully resistant to the antibiotics after three days. This research is also significant for cancer because cancer cells mutate readily and often...Insects, viruses could hold key for better human teamwork in disasters
... of rules govern the behavior of each insect for a given situation and the group's behavior emerges from su... ant behavior under threatening situations for any given application in engineering. However, the way ants "detect and propagate alarms and the interactions ...Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes
...rimordia, embryonic kidney tissue, if they are not given immune suppression drugs. Prior research by other scientists into the immune system's interactions with transplants had suggested that a second unsuccessful organ transplant can "wake up" the immune system and lead it to reject an earlier successful...Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips
... species that produces erythromycin, an antibiotic given to treat bronchitis, diphtheria, whooping cough, pneumonia and other conditions. Reverse engineering involves taking something apart to see how it works. For Kao, it means asking how one strain of Saccharopolyspora erythraea produces ten times the er...While on trail of dioxin, scientists pinpoint cancer target of green tea
...ter School of Medicine and Dentistry. The award is given at graduation each year to a student who has produced an outstanding thesis. The research also has earned Palermo awards from the Society of Toxicology in each of the last three years; the current research was published in the April 5 issue of the jo...... sites for establishing a new vaccine barrier. And given how fast raccoon rabies could spread, Real and colleagues make a strong case that halting its western march depends on a strategy based on early detection and high-powered intervention programs - a sensible approach for any infectious disease. ### ...... the flood of electronic signals on the air at any given time. When the transducer captures the signal, it is processed with advanced signal processing algorithms, specially developed by Marmarelis' group, to form the multi-band images. Different kinds of tissue allow slightly more, or slightly less of th...Ebola virus: from wildlife to dogs
...therefore become infected and excrete virus over a given period, thus becoming a potential source of infection for humans. This could explain certain as yet un-elucidated human infections. It now appears necessary to assess the role of dogs in Ebola fever outbreaks and take this risk into account in epidem...Active Vaccine Prevents Mice From Developing Prion Disease
... is also the first to use a mucosal prion vaccine, given by mouth rather than through the skin, which localizes the initial immune response to the gut and mainly stimulates an antibody response, says Dr. Wisniewski. "By giving our vaccine orally, we're stimulating an immune response mainly in the digestive...Researchers pioneer new gene therapy technique using natural repair process
...correct version of the mutant gene, and eventually given back to the patient, spawning the growth of healthy blood cells, Dr. Porteus said. ...Asymptomatic HIV babies could use earlier treatment
...illness, what kinds of treatment the children were given and the ages when they started treatment.?/p> The researchers divided the HIV-infected newborns into three groups: those born from 1988 to 1991, from 1992 to 1995 and from 1996 to 2001 based on the types of therapy available in those years. Membe...Shark attack worries? Driving to the beach is more deadly
... "There are millions of people in the water at any given moment of the day," he notes. "When you consider all of the people in the water at the same time, the number of shark attacks is very, very remote. Your chances of winning the lottery are greater than being attacked by a shark. "But when a shark at...New HIV drug candidate developed in Sweden
... "There are millions of people in the water at any given moment of the day," he notes. "When you consider all of the people in the water at the same time, the number of shark attacks is very, very remote. Your chances of winning the lottery are greater than being attacked by a shark. "But when a shark at...... "There are millions of people in the water at any given moment of the day," he notes. "When you consider all of the people in the water at the same time, the number of shark attacks is very, very remote. Your chances of winning the lottery are greater than being attacked by a shark. "But when a shark at...Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
...ical algorithm that predicts the precise effects a given compound will have on a cell’s molecular components or chemical processes. Using this tool, drug developers can design compounds that will act on only desired gene and protein targets, eliciting therapeutic responses free of unwanted side effects. T...New vaccine means bye-bye to bacteria in the lung
...acteria. Importantly, the mice could be repeatedly given the vaccine and the immune response against P. aeruginosa was boosted. Usually, adenovirus vectors do not allow for repeated infection. These results may be useful in the development of vaccines against bacterial pathogens. The findings that a vacci...High fidelity keeps human DNA assembly line humming
...orld of molecular biology, much attention has been given to how RNA is made. Burton explains that it is similar to an industrial assembly line, with DNA being a conveyer belt to load building blocks, or bases, called nucleoside triphosphates (NTPs) to hook up with a growing strand of RNA. Burton's insight...Census of Marine Life explorers surprised by diversity, density of Arctic creatures
...m-based skeleton, a finding that amazed scientists given the depth (about 4,500 meters) at which it was found. Research in the Southern Ocean is the most expensive in the world. The recent ANDEEP III expedition by icebreaker cost one Euro per second. The Antarctic Census will also harmonize with efforts ...Understanding how bacteria communicate may help scientists prevent disease
...son by a community of bacteria. The example often given is bioluminescence. Scientists noticed that once a population or colony of particular bacteria reached a certain size, the colony began to emit light. "Now many people realize that other important activities also depend upon a quorum, such as biofilm...