HIV-1 spread through six transmission lines in the UK
...rus has subsequently spread and evolved. However, given that the first UK cases of AIDS reported in 1982 were probably infected within a window of 10 years prior to that time, the currently circulating strains may not represent the first HIV-1 lineages within the UK . If earlier strains existed they may h...GeneNotes - A novel information management software for biologists
... integrated gene annotations to (a) identify genes given various types of gene IDs (e.g., RefSeq ID, GenBank ID, etc.), and (b) provide quick views of genes. GeneNotes is free for academic usage. The program and the tutorials are available at: http://bayes.fas.harvard.edu/genenotes/. GeneNotes provides a ...Glow-in-the-dark zebrafish at UH hold keys to biological clocks
...ith an instrument called a luminometer. "This has given us the tool we need to find other parts of systems that influence biological clocks," Cahill said. "We are optimistic that this will shed light upon such things as reproduction in other light-dependent animals." These findings have laid the groundwo...Sickle cell and protection against malaria
...i, Kenya, show that the protection against malaria given by carrying the gene for sickle cell haemoglobin may involve the immune system. Studying a group of children and adults in the Kilifi District of coastal Kenya, they found that this protection increased during childhood up to age 10, and then decline...Medical whistleblowers speak out
...accessed by state officials. These officials "were given unrestricted educational grants that were deposited into an off-the-books account - unregistered, unmonitored, literally operated out of a drawer." The officials, he said, were responsible for writing guidelines for the treatment of patients in the s...Study reveals new technique for fingerprinting environmental samples
...he intricate physical and biochemical details of a given environment without having to know the actual identities of the resident microbes. This finding is crucial for studies of microbes in the wild since the sheer number of different organisms present in nearly all environments makes it a daunting task t...Nanoparticle Breast Cancer Drug Approved by FDA
...es to avoid hypersensitivity reactions and must be given in infusions for up to three hours. Because Abrax...jection. Without toxic solvents, Abraxane could be given at higher doses than Taxol, which may account, in part, for the increased anti-tumor activity. In a...Different microarray systems more alike than previously thought
...tories in the Washington, D.C./Baltimore area were given identical samples of RNA -- DNA's cousin -- to ana...e in consideration of cost versus performance in a given experiment. Additional studies can also include more recently introduced versions of microarray plat...Live vaccines more effective against horse herpes virus
...ndings, many inactivated vaccines, especially when given too often, don't appear to do much good," said Osterrieder. ...Grasping metaphors: UC San Diego research ties brain area to figures of speech
...n hominids than other primates, the angular gyrus, given its strategic location at the crossroads of areas specialized for processing touch, hearing and vision, Ramachandran conjectures, is critical both to conceptual metaphors and to cross-modal abstractions more generally. "While it would be premature t...Protein helps regulate the genes of embryonic stem cells
...he precise nature of the histone modification, any given gene associated with modified histones is marked to be turned on or off. In the study, eed is the first protein shown to be required for the addition of a single methyl group to histone H3, said Montgomery. Knowing which proteins are responsible for...Measuring hormone cuts antibiotic use in half in pneumonia patients
...domly divided them into two groups. Once group was given the standard antibiotic treatment, while the other...re presumed to have viral pneumonia; they were not given antibiotics. The remaining 85% had high levels and were started on antibiotics. The researchers meas...Genetic therapy reverses nervous system damage in animal model of inherited human disease
...ideo comparing a cat with AMD to one that had been given gene therapy is available at www.mrw.interscience.wiley.com/suppmat/0364-5134/suppmat/2005/57/v57.3.355.html. ...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
... with soybean oil) did not. And p27 knock-out mice given a Western diet, full of fat and lacking calcium and vitamin D, formed the most number of tumors. The researchers then looked at the role that diet plays when expression of two tumor suppressor genes is reduced. The researchers mated mice that had on...To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter
...e same time, a way of "straying in time" so that a given pair hasn't lost all their descendants if one year's worth is wiped out. There is undoubtedly an environmental aspect in all of these, he says. The most obvious being when conditions in the home river are so degraded that salmon move elsewhere to spa...Putting ecology back into river restoration
...e ecologically healthy river that could exist at a given site. The second step should be to demonstrate tha...judging ecological success." The debate is timely given the many waterfront regeneration projects under way worldwide. But, Palmer argues, many such schemes...Protein prevents detrimental immune effects of bacterial sepsis
...ration. In fact, when annexin 1 knockout mice were given small doses of human recombinant annexin 1 in the ...s to use these new targets (e.g., a receptor for a given anti-inflammatory mediator) to develop better and safer drugs." The data for annexin 1 provide a new...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...uch a test, however, will require that patients be given the drug for a short period of time so that the ag... the effects of Tarceva were reduced when CDK2 was given back to the cells, so this shows us that CDK2 is the real target of Tarceva. "This presents a conce...The lopsided brain: Attention bias is shared by humans and birds
...ibit spatial pseudoneglect is somewhat surprising, given that birds lack a corpus collosum, the structure in human brains that is thought to facilitate rapid communication between the two hemispheres. In the past, such communication via the corpus collosum has been thought to form the basis for asymmetries...Master gene controls healing of skin in fruit flies and mammals
...arrier in insects and mammals have been conserved, given the differences in the molecular composition of insect cuticle and mammal skin. "The proteins that link together to form the insect cuticle and stratum corneum--the outer layer of mammal skin--are completely different," says McGinnis. "So it is rema...