Program finds lost genes in nematode genome
...hich house the coding machinery of proteins. While getting intron length is helpful for gene annotation, the process is 15 times slower than the typical, less accurate methods. Being able to define intron length has implications for the human genome, which is much larger than C. elegans and has an average in...Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
...ey can be absorbed." To sidestep the difficulty of getting these large protein drugs through the GI tract intact, pharmaceutical scientists have looked at other ways to deliver protein-based drugs-such as via needle-free injections or through inhalation. But, these delivery methods pose their own significant...Small worm yields big clue on muscle receptor action
...pplied. Using this preparation, Richmond was still getting muscle contraction when acetylcholine was applied to worms lacking any of five receptor subunits known to be sensitive to levamisole, a chemical that poisons nematodes. Two additional receptor subunits -- ACR-16 and ACR-8 -- identified using Vanderbi...Scripps research scientists identify infertility molecule
...lty that many women over the age of thirty have in getting pregnant. Successful conception depends on a variety of factors. A man has to produce an adequate amount of healthy sperm, and a woman has to produce healthy eggs. The sperm has to be able to travel up the fallopian tubes to reach the egg, and once ...To translate touch, the brain can quickly rearrange its sense of the body
...e this happened, they felt their left index finger getting longer as they felt their arm move. The team then tested how these bodily illusions rearranged the sense of touch. They touched subjects with two metal rods on the left index finger, and asked them to judge whether the distance between the rods was ...Purdue scientists may have found key to halting spinal cord damage
...rong with this approach, Shi said, it might not be getting at the root of some health problems. "Antioxidants are good scavengers of free radicals, and it's certainly wise to have plenty of them circulating in your bloodstream," he said. "The trouble is that when free radicals start attacking tissue, it hap...New tool reveals secrets of migrating cells
... studies (published in Science) we could see cells getting together, presumably signaling one another. In our current work, we observe cells that we believe have already gotten a signal beelining away," Robey said of her studies in the thymus, the immune system gland that weans baby T cells into activated he...Why are coyotes getting more aggressive?
...oid human contact. But recently, coyotes have been getting increasingly aggressive in the eastern United States, including southeastern New York state, attacking neighborhood pets on the fringe of urban and suburban areas. "This kind of aggressive behavior is usually the last stage before coyotes actually s...Gene expands malaria's invasion options
...f both genes are disrupted, it blocks both ways of getting in," he says. ...Hepatitis C responds best to combo of ribavirin and interferon, study concludes
... after six months, compared to 58 percent of those getting interferon plus ribavarin. Among those who had re...s did not respond, compared to 81 percent of those getting both drugs. Other measures reported by the researchers included patient status at the end of treatm...Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'
...e not aware of. In other words, thinking they were getting a pain drug actually allowed the participants to tolerate even more pain-inducing concentrated salt water than before. After each scan, the researchers asked the participants more questions about their mood, emotions and other aspects of how they fe...Gambling monkeys give insight into neural machinery of risk
...e, it seemed as if these monkeys got a high out of getting a big reward that obliterated any memory of all the losses that they would experience following that big reward," said Platt. Confident that they had developed a valid animal model that would reveal insights into the brain mechanism for assessing ri...Why were the HIV prevention trials in commercial sex workers abandoned?
...the male partner's consent, and the protestors are getting in the way of such development. "Activist groups have now managed to derail several PREP trials, arguably the most important studies for those at high risk of acquiring HIV infection around the globe." Lange is highly critical of the tactics used by...Slipping past the blood brain barrier: Research shows potential treatment for brain cancer
... animal model and the human condition. In terms of getting drugs across the blood brain barrier to fight cancer, there's not such a big difference. There's pretty much the same rules in any blood brain barrier - be it in a mouse or human." Laura Jaeger, the lead author of the study and a doctoral student in...Logging changed ecological balance for monkeys, damaged health
...The guenons in the logged forest, they report, are getting much less protein and vital minerals than their counterparts in undisturbed forests. Recovery of the forest also has been hampered by the growth of acanthus, an invasive shrub that has overwhelmed much of the forest floor where trees were removed, G...Affymetrix and ParAllele Launch Industry's Most Comprehensive Product Line for Targeted Genotyping
...The guenons in the logged forest, they report, are getting much less protein and vital minerals than their counterparts in undisturbed forests. Recovery of the forest also has been hampered by the growth of acanthus, an invasive shrub that has overwhelmed much of the forest floor where trees were removed, G...President Bush's cut to AIDS prevention in Africa would be devastating
...The guenons in the logged forest, they report, are getting much less protein and vital minerals than their counterparts in undisturbed forests. Recovery of the forest also has been hampered by the growth of acanthus, an invasive shrub that has overwhelmed much of the forest floor where trees were removed, G...Beauty queens urge girls not to sacrifice their bones
...osis is already a huge health problem in Asia, and getting more serious every day- in 45 years (by 2050), one out of every two fractures in the world will occur in Asia. All women and men should take immediate action to review their life styles and take the IOF One Minute Osteoporosis Risk Test. Maximum bo...UIC researchers show protein routes messages in nerve cells
...e mutated codes for a protein that is critical for getting those receptors to the right place at the right time." Featherstone and his colleagues found that a protein called coracle -- known as 4.1 in humans -- links receptors on a nerve cell's membrane to its internal structure, or cytoskeleton. Because 4....Lands surface change on Alaska tundra creating longer, warmer summers in Arctic
... is pretty dramatic," Epstein said. "The tundra is getting greener, and there is a noticeable increase in shrubs. This is observable from satellite data and by observations on the ground. Native American people in the region and nearby areas also have noted the changes in weather and vegetation." Because th...