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University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

... structure after it has been built."The problem is getting cells into the interior of these constructionsas they naturally stick to the sides of whatever they are beinginserted into. If they stick to the sides then this limits the numberof cells which can grow into tissues, and the lack of penetration alsoli...

Growth in the sea comes down to a struggle for iron

...artin died in 1993 just as tests of his ideas were getting underway, but scientists have embarked on a series of experiments in three major areas of the world's oceans. "The three areas are the Southern Ocean around Antarctica, the equatorial Pacific out to about 140 degrees west and the sub-Arctic Pacific,...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...sestem cells that "home" to the muscle that is not getting enough blood.These stem cells include endothelial progenitor cells (EPCs), which isthe type of cell needed to make new blood vessels and to repair damagedones.Patients in the clinical trial will be given an injection of either agrowth factor called G...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...able technical challenges, including difficulty in getting gp120 to form good crystals. "Without very well-ordered crystals you get a very blurry picture," explains Harrison. "It took a very long time, and lots of computational work, to get that picture to sharpen up enough to get an answer." One of the la...

Timing is everything: First step in protein building revealed

...e on theyeast ribosome prevents the machinery from getting started. Only afterits release from the complex can the ribosome start making proteins."No one had any idea when eIF1 was released from the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," say...

Tiny particles could solve billion-dollar problem

... at more than $5 billion. The typical approach to getting rid of TCE involves pumping polluted groundwater to the surface, where it can be exposed to chemical catalysts or microorganisms that break the TCE down into less toxic or non-toxic constituents. In general, chemical catalysis offers faster reactions...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion of using protein “bar...

New species from old data

...develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion of using protein “bar...

Cracking the olfactory code in bees

...develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion of using protein “bar...

Signaling protein builds bigger, better bones in mice

...develop a variety of proteomic diagnostic tests is getting better and we are getting more reproducible results.? Researchers worldwide are excited about the notion of using protein “bar...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...e,called telomerase, which prevents telomeres from getting too short socells can keep dividing. Telomerase is not used by healthy cells, andhas been identified as a logical target for anticancer therapeutics.However, recent studies indicate that for this therapy to be effective,telomeres must be in a critica...

GATA: a graphic alignment tool for comparative sequence analysis

...e,called telomerase, which prevents telomeres from getting too short socells can keep dividing. Telomerase is not used by healthy cells, andhas been identified as a logical target for anticancer therapeutics.However, recent studies indicate that for this therapy to be effective,telomeres must be in a critica...

U-M scientist to talk about tissue engineering at AAAS

...n cells to do tricks in a laboratory---things like getting soft cells from the mouth's lining to form bone. But in the real world, accomplishing such feats is more complex. Regenerating the jaw bone of a person undergoing radiation therapy for cancer means managing the constant bacteria bath of a human mout...

Genome-wide mouse study yields link to human leukemia

...essor genes help control cancer by identifying and getting rid of defective cells before they have a chance to mature and divide. When tumor suppressor genes lose that ability ?as they can if they are silenced through methylation or some other process, it gives cancer a chance to establish a foothold and spr...

Sea skate experiment sheds light on human cell transport

...led with phosphorylation, is a broad mechanism for getting substances in and out of cells," Goldstein said. "The idea that we can apply this knowledge to other cells and other animals ?including humans ?is what makes the findings exciting." In type 1 diabetes, cells lose their ability to transport glucose. ...

Study: Soap And Water Work Best In Ridding Hands Of Disease Viruses

...ygiene products shows that nothing works better in getting rid of disease-causing viruses than simply washing one’s hands with good old-fashioned soap and water. Among the viruses soapy hand washing flushes down the drain is the one that causes the common cold. Other removable viruses cause hepatitis A, acu...

New SARS Protein Linked To Important Cell Doorway

...s revealed that part of the protein specializes in getting orf7a to the Golgi apparatus—the structure cells use to prepare proteins for transport to the cell surface--and keeping it there. Plans for follow-up include studies of a recently produced version of the SARS virus where orf7a has been genetically k...

Nano-Probes Allow an Inside Look at Cell Nuclei

... knew we could get quantum dots inside a cell, but getting them through the nuclear membrane is very difficul...long-term biological events. "The toughest part is getting inside the nucleus, and we have already cleared that hurdle." Chen and Gerion's research was publis...

Bird Brains Show How Trial and Error May Contribute to Learning

...experimenting with different things, and gradually getting better," said senior author Michael Brainard, assistant professor of physiology at UCSF, whose lab is funded in part by a grant from HHMI. "It makes sense that one part of the brain has as part of its job introducing that kind of variability." Kao b...

Chemists identify key gene in development of type 1 diabetes

...mplications minimized by following a healthy diet, getting exercise and taking prescribed medications as directed, according to health experts. The Institute for Medical Research at North Shore-LIJ provided funding for this study. The American Chemical Society is a nonprofit organization, chartered by the ...

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