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A gene's first 'kiss' sets off that affair known as puberty

...It takes two to tango," whereby a signal literally gets turned on by a molecule that is produced by a gene aptly named KiSS-1. The couple ?a biochemical equivalent to Adam and Eve ?makes its sudden appearance in a region of the brain called the hypothalamus just as puberty begins, according to a study pu...

Growth in the sea comes down to a struggle for iron

...ty in choppy seas, a benefit to Wells who normally gets seasick on these voyages. For nine days, she steamed northwest to rendezvous with a research vessel from the University of Tokyo, the Hakuho Maru, carrying a large group of Japanese scientists. The Japanese project is known as SEEDS (Subarctic Pacif...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...al benefits of plaque-clearing treatments and also gets usrethinking our theories on how plaques cause nerve cell damage."Prior to the experiment, Holtzman and some other scientists hadregarded plaque damage to nerve cells as a fait accompli--somethingthat the plaques only needed to inflict on nerve cells...

Key molecule in plant photo-protection identified

...al benefits of plaque-clearing treatments and also gets usrethinking our theories on how plaques cause nerve cell damage."Prior to the experiment, Holtzman and some other scientists hadregarded plaque damage to nerve cells as a fait accompli--somethingthat the plaques only needed to inflict on nerve cells...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...prevents them from differentiating completely. "It gets the show going, but at the same time, prevents the final act," says Epstein. "I call this dual function a "biological capacitor," because Pax3 tells the cell: Get ready to go, but at the same time won't let it proceed." Pangenes Express Behavioral Q...

Poplar trees redirect resources in response to simulated attack

...e scientists have not yet determined if more sugar gets stored in the plants' roots, a key component of the theory. "Because the radiotracer has such a short half-life (20.4 minutes), we can see that more is going to the roots, but not the chemical form it takes there," Ferrieri said. "We will have to do ...

Scientists rid stem cell culture of key animal cells

...onprofit research institute. "This work completely gets rid of the need for feeder cells," says Xu. "It also significantly reduces the daily labor of preparing the feeder cell-conditioned medium." "It is important that the culture of human ES cells be simplified so that the average scientist can use them...

South America's vast pantanal wetland may become next everglades, UNU experts warn

...on. Without cattle to eat or step on the grass, it gets dry and more easily burns, leading to more frequent fires which destroy flood-adapted trees, in which aquatic birds nest, while killing swamp deer and other animals. (The Pantanal's other fauna includes giant anteaters, armadillos, capybara, the Braz...

Potential treatments for neurofibromatosis

...m lack of blood vessel support. Neurofibromatosis gets its name from neurofibromas, the disfiguring and often painful tumors that grow along nerve coverings and form on or under the skin. In most patients, the tumors begin to appear in adolescence or adulthood. A patient may develop hundreds of neurofibr...

Epstein-Barr virus protein crucial to its role in blood cancers

... cell cycle of the usually quiescent human B cells gets a jump start, which ultimately initiates uncontrolled growth. EBV, a member of the herpesvirus family and one of the most common human viruses, plays a role in cancers such as lymphoproliferative diseases in transplant or AIDS patients, Burkitt's ly...

Defensins neutralize anthrax toxin

... cell cycle of the usually quiescent human B cells gets a jump start, which ultimately initiates uncontrolled growth. EBV, a member of the herpesvirus family and one of the most common human viruses, plays a role in cancers such as lymphoproliferative diseases in transplant or AIDS patients, Burkitt's ly...

Computational Method Speeds Mapping of Cell Signaling Networks

...ntists have been studying how external information gets transmitted from outside of cells to the control centers inside them that trigger particular responses. But cell signaling networks are so complex that mapping them has been a slow, arduous process. Now, a research team from Stanford, MIT and Harvar...

Glow-in-the-dark zebrafish at UH hold keys to biological clocks

...ish contain something in their genetic makeup that gets their clocks ticking without parental influence, however, we determined that it does take some sort of environmental input for the clock to start. In this case it was exposure to light/dark cycles after the fourth day of development, about the age wh...

Birds brains reveal source of songs

...s memory of the father's song. Gradually, the bird gets it right more often and eventually sings only the songs of its elders. ...

Researchers make gains in understanding antibiotic resistance

...mutates to avoid the effects of one drug, it still gets hit by another. However, in the case of these antibiotics, the binding sites are linked in one molecule. It's like a multi-drug treatment, but in one compound," he said. ...

Harmful chemicals may reprogram gene response to estrogen

...f gene-environment interaction that determines who gets cancer and who doesn't." According to Walker, the increase in frequency and size of the uterine tumors is due to DES' ability to influence estrogen, a female hormone that is involved in promoting the growth of tumors by regulating the activity of ke...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...ic blueprint isn't delivered and the protein never gets made. "Gene silencing is an example of using "molecular scissors" at its most advanced level," Raoul explains. Raoul and colleagues used RNA interference to reduce levels of mutant SOD1 protein in the spinal cords of transgenic ALS mice (mice bred ...

NASA study finds snow melt causes large ocean plant blooms

...toplankton breaks down and decomposes, more oxygen gets consumed in the process. An increase in phytoplankton could therefore cause oxygen deficiencies in the Arabian Sea to spread, leading to fish mortality. Oxygen-depleted waters also provide the perfect environment for the growth of a specialized grou...

Some Brain Cells 'Change Channels' To Fine-tune The Message

...the cells' AMPA receptors, and so too much calcium gets inside. If these threatened nerve cells can swap their calcium-allowing channels for the kind that keeps calcium out, it might be possible to harness that switch to prevent the cells from dying. "But that's a big 'if' at this point," says Huganir. ...

Medical whistleblowers speak out

...tive relationship" with industry, and that the FDA gets money from drug companies through the Prescription Drug User Fee Act "to approve new drugs and approve them more quickly." A senior official at the FDA, said Graham, had told him, "industry is our client." "The pharma-FDA complex has to be dismantle...

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