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Tag: "genome" at biology news

Unraveling the viral mechanism

.... I think the virus does the same thing. The virus genome has to enter the capsid during the birth of the virus and then inject into the cell during infection. It has to come in and get out easily. The hub anchors the tail spikes, but is also a conduit for the DNA to get in and out." Below is the "portal" ...

New method enables gene disruption in destructive fungal pathogen

..."The development of this protocol is timely as the genome sequence of A. brassicicola is scheduled for compl...dies with the weedy mustard plant Arabidopsis. The genome sequence of Arabidopsis was determined in 2001 and many methods are available to ascertain gene func...

Where 'jumping genes' fear to tread

... Genome Research that large segments of the human genome are conspicuously devoid of ubiquitous mobile DNA ...enetic elements are scattered throughout the human genome ?separated, on average, by only 500 base pairs. But Dr. John Mattick's laboratory at the University...

Scientists identify molecular structure of key viral protein

... cellular membranes, permitting entry of the viral genome into the cell. "What we've learned about the structure of the parainfluenza virus 5 fusion protein will be directly applicable to the whole family of paramyxoviruses," said virologist Robert A. Lamb, John Evans Professor of Biochemistry, Molecular ...

Tandem transcripts team together

...ists describe a widespread phenomenon in the human genome called transcription-induced chimerism (TIC), wher...mates that at least 2-5% of the genes in the human genome are involved in these events. "In a certain way, this phenomenon challenges our very concept of a g...

Genome changes tracked during multiple myeloma initiation, progression and treatment

...rs. "This integrated and detailed view of the MM genome is consistent with the concept of widespread chang...on a broader scale in relation to the human cancer genome project, their results will serve to direct costly sequencing efforts toward those specific regions ...

Virginia Bioinformatics Institutes launches microbial database

...le microbial database to host a range of microbial genome sequences. The VBI Microbial Database (VMD), whic...cleic Acids Research (Vol.34, D379-D381), contains genome sequence and annotation data for the plant pathogens Phytophthora sojae and Phytophthora ramorum. Th...

Researchers discover way to transport environmental arsenic to plant leaves in new clean-up strategy

...identified a single gene, ACR2, in the Arabidopsis genome as one that allows the plants to move sequestered arsenic in roots. By engineering plant lines with a silenced ACR2 gene, they discovered they could get 16-fold more arsenic in shoots than in natural wild-type Arabidopsis. This experiment identified ...

Biologists develop genome-wide map of miRNA-mRNA interactions

...ts, the research team examined the function of the genome of C. elegans, the first animal species whose genome was completely sequenced and a model organism to study how embryos develop. Using PicTar, an algorit...

Berkeley researchers lay groundwork for cell version of DNA chip

...eural networks. "Just as DNA chips revolutionized genome analysis, we hope to make cell chips (self-assembled arrays of cells on a thumbnail-sized chip) using our DNA-based cell adhesion strategy," said Ravi Chandra, a researcher affiliated with Berkeley Lab's Physical Biosciences Division and UC Berkeley'...

Variation in bitter-taste receptor gene increases risk for alcoholism

...tigation, Goate's team took advantage of available genome sequence databases to speed work in identifying and studying genes on chromosome 7. She says data from the Human Genome Project allowed the investigators to more quickly recognize individual variations in genes, called polymorphisms, that can influen...

MBL leads effort to update E. coli genome

... As such, the accuracy and completeness of E.coli genome information is of great importance to the scientif...efforts of scientists working independently on the genome of the E.coli K-12 strain, an international team of biologists, led by MBL (Marine Biological Labora...

Strawberries by design

...icient transfer of specific DNA sequences into the genome of strawberry. The scientists have used Agrobacterium tumefaciens, nature's genetic engineer, to introduce DNA into the woodland or alpine strawberry Fragaria vesca. The method takes advantage of Agrobacterium's circular DNA molecule (T-DNA) to del...

'Genetic network' guards against lethal DNA damage

...ions of the 5,000 non-essential genes in the yeast genome would require about 25 million tests, he added. In the current study, 74 genes were tested in pair-wise combination with the 5,000 non-essential genes, a feat approximately equivalent to 370,000 gene-pair tests. The Hopkins team used a technology kn...

Soil-bound prions that cause CWD remain infectious

...hanisms of microbial killing in CGD. Comparing the genome of this organism to other 13 available genomes of CGD pathogens may provide clues to virulence properties that they share in common," according to the article. ...

Scientists discover a new disease-causing bacterium in an immune-compromised patient

...hanisms of microbial killing in CGD. Comparing the genome of this organism to other 13 available genomes of CGD pathogens may provide clues to virulence properties that they share in common," according to the article. ...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...ymetrix Inc. of Santa Clara, Calif., to accelerate genome association studies to find the genetic roots of w...e public domain. Background information on whole genome association studies can be found at www.genome.gov/17516714 . Background information on environment...

New mechanism for essential genome-wide gene silencing identified

...0 percent of the roughly 25,000 genes in the human genome are activated, or "on," at any given time in a par...ple. Gene silencing is also thought to protect the genome from viruses and other potentially damaging entities, thus preserving genetic integrity. In a new s...

Cracking the genetic code for control of gene expression

...is work are published in Cell, in January 2006. A genome milestone was reached in 2001 when sequencing of the human genome was completed. This has been followed by complete chemical read-outs of DNA sequence for several spe...

Supersized 'island' of resistance genes discovered in an infectious bacterium

... is a demonstration of the efficiency of the whole genome approach in characterizing new pathogens," said Je...ding to the study. "It is like the A. baumannii genome is 'anticipating' any antibacterial challenge by setting up some kind of easily accessible 'shelves'...

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