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Tag: "genetically" at biology news

Early-stage immune system control of HIV may depend on inherited factors

...es that an individual expresses, something that is genetically determined, seems to have a significant impact on the specificity and strength of that response. "Identifying the HIV epitopes [viral fragments] that are particularly good at priming an early T cell response may be important to vaccine design, and...

Living view in animals shows how cells decide to make proteins

...ent. As a model system to study, the scientists genetically created a "glowing" mouse. The mouse carried in its FGFR2 gene a green fluorescent tag that would glow when a common type of silencer, called an "intronic silencer," chopped out a specific exon, called IIIb. In this way, the scientists could track...

With fruit fly sex, researchers find mind-body connection

... pathways," McKeown said. "If sexual behaviors are genetically controlled in humans, I expect that this system would be just as much, if not more, complicated." ...

Chronic jet-lag conditions hasten death in aged mice

...unrelated study: A surprising fraction of old (but genetically altered) rats exposed to a six-hour advance in their light cycle died after the shift in schedule. In the new work, the researchers examined the mortality link in earnest by looking at how young mice and old mice fared when subjected to two differ...

Invasive ants territorial when neighbors are not kin

...hip between behavior and genetics. Ants that were genetically similar had peaceful relations. Ants that were genetically different attacked each other. "Our results are strong evidence that lack of genetic diversity per...

Science researchers genetically transform immune cells into tumor fighters

A team of researchers has genetically engineered normal immune cells to become specializ...lls from people with advanced metastatic melanoma, genetically engineering these normal cells to carry the receptor that recognizes melanoma cells and returning th...

Evolution of influenza A virus

...tate. Comparative analysis of the samples revealed genetically distinct viral strains circulate across the state within any one season and occasionally exchange genes through reassortment. These results indicate that adaptive evolution occurs only sporadically in influenza virus, and that influenza virus div...

Hundreds of thousands of viral species present in the world's oceans

...ples from the British Columbia coast were the most genetically diverse (consistent with its nutrient-rich environment). The other three samples showed increasing diversity with decreasing latitude, a trend that parallels previous findings from terrestrial ecosystems. In fact, the researchers predict that the wor...

Researchers seek to design first treatment for neuroAIDS

...HAD to determine that they work in a living system genetically similar to humans. If these tests are successful, human studies will proceed with an existing MLK3 inhibitor, CEP-1347, developed by Pennsylvania-based biotech Cephalon. Ira Shoulson, M.D., professor of Neurology at the University of Rochester Medic...

Weighty viruses

...ding of the structure and characteristics of these genetically varied little organisms, it would be highly useful to be able to determine their masses and how much these vary within a given population. Researchers in Taiwan have now used very gentle ionization techniques and a miniaturized ion trap of their own ...

Sequencing of the oyster mushroom genome

...ll be the first edible mushroom in the world to be genetically sequenced but, apart from its characteristics that make its consumption beneficial (rich in vitamins and proteins), this fungus is a model for studying the CO 2 cycle ?carbon dioxide being one of the principal gases of the greenhouse effect ?and hol...

Tarantula venom and chili peppers target same pain sensor

... the peptides, which they call vanillotoxins. Mice genetically engineered to lack capsaicin receptors did not respond. ...

Scientists show drug can counteract muscular dystrophy in mice

...o Duchenne muscular dystrophy in humans, the other genetically altered to develop a form of dystrophy similar to the human limb-girdle muscular dystrophy. At 45 to 90 days of age, the muscles of the MD mice showed much fibrous tissue and infiltration of inflammatory cells. Unlike healthy mice, the mice with MD ...

Scientists discover way to block growth of prostate cancer cells

...and inhibited tumour development in mice that were genetically engineered to spontaneously develop prostate cance...ostate cancer cells. They injected MDL into the genetically engineered mice and found that it inhibited polyamine oxidation and reduced oxidative stress in the ...

New research identifies gene important for nicotine's effects on the brain

...s of nicotine. Their new study shows that using a genetically altered virus that blocks CREB activity in the nuc...r types of abuse. Picciotto's research used both genetically engineered mice with altered nicotine receptors and viruses that could block CREB function. She and ...

Genome archaeology illuminates the genetic engineering debate

...t genomic evolution may well fuel the fires of the genetically modified organism (GMO) controversy. "Our findings elucidate an active evolutionary process in which nature inserts genes much like modern biotechnologists do. Now we must reassess the allegations that biotechnologists perform 'unnatural acts,' the...

Eating protein boosts hormone that staves off hunger

...y found. In addition, the researchers found that genetically modified mice unable to produce PYY ate more and became markedly obese. The genetically modified mice were also resistant to the beneficial effects of a high-protein diet, the researchers ...

Researchers identify neurons that assign value during learning

...ts neuronal simplicity and the fact that it can be genetically manipulated, the fruit fly offers a favorable study case to address a principal question in the field of learning and behavior: Which neurons attribute attractive or aversive values to so-called neutral stimuli, such as odors, in the course of associ...

Researchers identify a key regulator for skin stem cells

...sought to pinpoint which genes Tcf3 controls. They genetically engineered a mouse in which they could switch the Tcf3 gene on at will in skin cells. They then used DNA microarrays to analyze which genes were affected when Tcf3 was activated. Microarrays, also known as "gene chips," enable scientists to determine...

Studies find general mechanism of cellular aging

...6INK4a (the gene was deleted, or 'knocked out") or genetically altered to have an excess of the protein to a degree seen in aging. According to Sharpless, islet proliferation persisted in p16INK4a -deficient animals as they aged, "almost as if they were younger animals." In mice with an excess of p16INK4a, "is...

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