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Tag: "genetic" at biology news

Mouse gene shows new mechanism behind cardiac infarction in man

...e without. “This is an example of how an unbiased genetic strategy based on a mice model can teach us more about common human diseases,?says researcher Jacob Lagercrantz of the Gustav V research institute, Karolinska Institutet. The gene codes for a protein called OX40L, which is involved in the activation...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...ng's sarcoma tumors. Once inside these cells, the genetic machinery of the tumor cells are effectively silen...ns, including the ability to deliver these bits of genetic material in high concentrations to specific tumor sites, while avoiding degradation. To overcome th...

Protein helps regulate the genes of embryonic stem cells

... Researchers five decades ago worked to crack the genetic code, the nucleic acid sequence of As, Cs, Gs and ...formation, just as the DNA sequence is the unit of genetic information." Depending on the precise nature of the histone modification, any given gene associated...

Chromosome Deletion Predicts Aggressive Neuroblastoma

...blastoma. A new study suggests that detecting this genetic deletion during the initial evaluation of children...ve without having amplified MYCN. "The deletion of genetic material on chromosome 11 may account for a significant percentage of these high-risk neuroblastomas...

Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance

...hers to look for a single variation in the complex genetic code and know all the variations associated with it, since all are part of the same haplotype. The Maine research group challenges that proposal, demonstrating that genes within a haplotype function independently. The group included Dr. Antonio Plan...

Double triumph in stem cell quest

...uld he be sure that the stembrids contain only the genetic material of the adult donors? Verlinsky's response was that he fused male adult cells with a female ESC line, and the resulting cells were male. However, Verlinsky's team has not yet tested the HLA proteins on the cell surface to prove that the stemb...

Grizzlies set to invade high Arctic?

...the world's premier bear DNA labs. The result: the genetic analysis pointed to a male barren ground grizzly bear, rather than a Viscount Melville polar bear, the variety known to inhabit the Melville Island area. During the past 15 years there have been more and more sightings for barren-ground grizzlies on...

MUHC scientists describe genetic resistance to rampant virus

MUHC researchers have defined genetic resistance to the widespread virus, cytomegaloviru...ains in an attempt to describe the nature of their genetic resistance. "This research marks our second discovery of genetic resistance to CMV," she says. Most ...

New World founders small in number

...h addresses shortcomings in traditional population genetic studies that rely on just one gene and that assume...A sequences from nine loci, so that the population genetic history could be found despite variation among genes. He also added an additional parameter to stand...

Scientists discover that three overlapping signals in embryo help get the backbone right

...vis. Lab specimens of X. tropicalis also have less genetic variation than outbred populations of X. laevis, a... Harland is pioneering the use of X. tropicalis in genetic studies, creating numerous mutants that can be used to explore the role of various genes in developm...

Genetic therapy reverses nervous system damage in animal model of inherited human disease

...in, researchers have treated a naturally occurring genetic disease in cats. This is the first genetic disease affecting the central nervous system to be successfully treated in an animal larger than mic...

Advancements In Genomics Foster Deep Sea Discoveries

... University of Padova (Italy), presented the first genetic blueprint for bacterial life in a cold deep-sea en...resented a detailed analysis of how the bacteria’s genetic makeup allows it to function in high-pressure environments. These findings may help lay the groundwo...

Study reveals dramatic difference between breast cancers in US and Africa

...s study was 44. Studies suggest that the rate and genetic profiles of breast cancers in African American wom...based at the University of Chicago to sort out the genetic and environmental factors that contribute to breast cancer. The study will look at the genes, lifest...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...earch Hospital and colleagues used a comprehensive genetic screening technique to search for genes that are d...ed in disparate response to these drugs. Specific genetic signatures related to ALL treatment failure and chemotherapeutic cross-resistance were more effectiv...

NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses

... a high-fat Western-style diet - even when several genetic brakes to cancer formation were missing in the animals, say researchers from the Albert Einstein Cancer Center. The investigators, who presented their findings at the 96th Annual Meeting of the American Association for Cancer Research, say that whil...

Doctors closer to using gene analysis to help trauma patients

A genetic tool with the potential to identify which trauma a...atic injuries. Researchers want to understand the genetic features that enhance a patient’s recovery as well as the elements that cause people to die sometime...

To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter

...his out" in any cognitive way, that there are some genetic controls at work that scientists don't fully understand, he says. The same is true of fish that have gone to sea but don't return to their stream of origin to spawn, instead straying to some other waterway. The process of straying is entirely myste...

UCLA scientists store materials in cells natural vaults

...se Tay Sachs disease * DNA delivery to correct genetic mutations * Timed release of drugs, enzymes and DNA * Extracting and imprisoning cellular toxins into the vault * Stabilizing proteins in vaults to increase their lifespans AUTHORS: Leonard Rome, professor of biological chemistry and se...

Study reveals candidate targets for anti-retroviral therapeutics

... of Genome Research. Many organisms harbor mobile genetic elements that are non-pathogenic molecular relativ...) allowing them to search through large amounts of genetic and biochemical data to identify "clusters," or related groups of genes, that are most likely to aff...

Oldest fossil human protein ever sequenced

... similar way to DNA, to provide information on the genetic relationships between extinct and living species. As ancient DNA rarely survives, this new method opens up the possibility of determining these relationships in much older fossils which no longer contain DNA. The research presents the sequence for t...

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