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Discovery Promises Simpler Therapy for Sickle Cell Disease
...pite the fact that the disease stems from a single genetic defect, Stamler said. "This finding, if verified in clinical trials, could change physicians' approach to sickle cell disease," Stamler said. "Current efforts for managing the disease completely miss the role that red blood cell-derived nitric oxide...Researchers discover chemical compounds that affect plant growth
...hemical genomics, the team could identify valuable genetic characteristics beyond the reach of conventional m... membrane components. Combined with the formidable genetic mapping and information available from the Arabidopsis plant, chemical genomics is becoming a powerf...Increased risk of osteoporosis associated with gene that one in five people have
About nineteen percent of people have a genetic variation that may increase susceptibility to oste...t least one year past menopause. They analyzed the genetic sequence of each woman's CYP1A1 gene to identify which of the genetic variants they possessed. One ...Key mechanism in genetic inheritance during cell division identified
A key mechanism in the passing of genetic material from a parent cell to daughter cells appe...ntribute to cancer and birth defects. From various genetic experiments we know that the activity of a 10-protein complex of kinetochores, called Dam1, is respo...Gene Therapy Cures Inherited Liver Disease In Rats
...o long term effect. It does not become part of the genetic machinery of the cell and poses no risk of causing cancer, said Lee. "This approach would be applicable to many diseases where you are trying to put something back, targeting the liver," he said. He is hesitant to predict when the treatment can be ...Gene therapy promising for growing tooth-supporting bone
...e virus' ability to enter into cells and use their genetic machinery. Once inside the cell, the viruses help...ecause the team did not want to make any permanent genetic changes. The gene acted quickly to get bone growth started, then disappeared within about 28 days. ...Glow-in-the-dark zebrafish at UH hold keys to biological clocks
...hese per3-luc zebrafish contain something in their genetic makeup that gets their clocks ticking without parental influence, however, we determined that it does take some sort of environmental input for the clock to start. In this case it was exposure to light/dark cycles after the fourth day of development,...New lab technique identifies high levels of pathogens in therapy pool
A research team using a novel genetic cloning and sequencing technique has identified a surprisingly high number of airborne pathogens in a Midwest therapy pool, pointing to the need for closer scrutiny of public hot pools, says a new study. Led by Washington University in St. Louis and...Researchers find new genes necessary to make embryo
... development. The new findings also probe into how genetic networks are built and how they could evolve. The...hers to have a first genome-wide look at a classic genetic phenomenon called "partial penetrance" ?whereby the same genetic mutations may elicit different resu...Researchers rein in regulatory RNAs
...hat poly(A)+ mRNAs are major mediators in flows of genetic information," Abe explains. "However, the information obtained from this study implies that some classes of poly(A)-negative nuclear RNA may have important biological functions." Among these functions may be the regulation of gene expression on a do...Scientists identify molecule that regulates well-known tumor suppressor
...nd the University of Toronto and colleagues used a genetic screening method in fruit flies and identified the molecule DJ-1 as a PTEN suppressor. In studies with mammalian cells, low levels of DJ-1 correlated with decreased PKB/Akt activity, while increased DJ-1 led to activation of PKB/Akt and enhanced cel...Newly discovered pathway might help in design of cancer drugs
...ing up with the cancer cells' DNA and sticking its genetic code together so it dies. Our discovery takes that a step further, establishing that there is a way to efficiently create this type of damage by modifying the DNA itself." In the lab, Greenberg and his team used organic chemistry to create a synthet...Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
...nce on social behaviors that have reproductive and genetic consequences." Diverse emotions occur, but reward response primary "It's a stark reminder that the mind truly is in the brain," noted Lucy L. Brown of the Albert Einstein College of Medicine. "We humans are built to experience magical feelings like...Navigating an integrated yeast network
...haromyces cerevisae: protein-protein interactions, genetic interactions, transcriptional regulation, sequence homology and expression correlation. The authors are the first to integrate so many types of data to search for network motifs. The authors conclude that most network motifs found in the integrated S...Researchers make gains in understanding antibiotic resistance
... molecular machine responsible for translating the genetic information on messenger RNA into the long strings of amino acids called polypeptides that are used to build the cell's enzymatic machinery. "These antibiotics are clinically very important, and resistance to such antibiotics is a major health probl...Harmful chemicals may reprogram gene response to estrogen
...genes respond to the female hormone estrogen. This genetic reprogramming may determine whether people with a genetic predisposition for a disease actually develop the disease. The new research shows that when rats wi...Disease diagnosis, biodefense among UH chemical research projects
...eic acids (DNA and RNA) is important in diagnosing genetic diseases, genome sequencing and making DNA-based vaccines for diseases like Ebola and HIV. ### For more information about the ACS meeting and to access a schedule of presenters and presentations, visit http://acswebcontent.acs.org/nationalmeeting/s...Silence the gene, save the cell: RNA interference as promising therapy for ALS
...that protects cells from invading viruses or other genetic threats. It works by interrupting messenger RNA as it transfers the genetic code for a protein from the nucleus to the site in the cell where the protein is synthesized. To tr...Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis
...from the genome of HSCs and progenitor cells. Upon genetic deletion, these mice developed anemia and had severely reduced numbers of bone marrow (BM) cells, such as HSCs and progenitor cells. This was strong evidence that Mcl-1 was needed to maintain these cell populations. The team also demonstrated that B...Revolutionary nanotechnology illuminates brain cells at work
...to overcome this obstacle by successfully applying genetic nanotechnology using molecular sensors to view cha...of glutamate. The sensors are encoded by genes and genetic ZIP codes can be used to target the sensors to any location in the cell and to its surface. "We use...Other Tagscontinual 2turned 2turned 3turned 4turned 5turned 6turned 7turned 8turned 9turned 10leading 2leading 3leading 4leading 5leading 6leading 7leading 8leading 9leading 10resist 2resist 3age 2age 3age 4age 5age 6age 7age 8age 9age 10years 2years 3years 4years 5years 6years 7years 8years 9years 10add 2add 3add 4add 5add 6add 7add 8add 9text 2Other Contentsendosymbiosisendosymbiosisendothermentropyentropyenvironmentenvironmentenvironmentenvironmentenvironmentenvironmentenvironmentenvironmentenvironmentdamagedamagedamagedamagedamagedamagedamagedamagedamagedamageenvironmentalenvironmentalenvironmentalenvironmentalenvironmentalenvironmentalenvironmentalenvironmentaleosinophilseosinophils
(Date:12/4/2009)...skovar, a Texas AgriLife Research plant physiologi...nter in Uvalde, has been investigating ways to hel...n from the greenhouse to the field. , "This rese...ibly even the further profitability of some vegeta... plants that will establish well," Leskovar said. ...
(Date:12/4/2009)...lable in German . , A new study of the Max Pl... understand the positive effect of dietary restric...ferent organisms (fruit flies and mice) have shown... with a potential negative side effect of diminish...ess frequently with a reduced litter size on a low...
(Date:12/3/2009)...n new information and adapt to changes in our dail...ies, appears to lie in the minute junctions where ...by NYU Langone Medicine Center researchers. The st...Nature . , The scientists, led by Wen-Biao Gan,...cience at NYU School of Medicine, discovered that ...
Breaking Biology News(10 mins):Texas AgriLife researchers helping 2Texas AgriLife researchers helping 3Texas AgriLife researchers helping 4How nutrition affects healthy aging 2Lifelong memories linked to stable nerve connections 2NIDDK announces availability of more current kidney disease data 58802 1NIDDK announces availability of more current kidney disease data 58802 2The real world of a forensic scientist 10247 1The real world of a forensic scientist 10247 2Uncertainty Surrounds Testing for Alzheimers 58797 1Uncertainty Surrounds Testing for Alzheimers 58797 2Uncertainty Surrounds Testing for Alzheimers 58797 3(Date:12/4/2009)...w study shows that muscle cells grown in the lab c...properly. The work, performed in dogs and rats, mi... such as gastric reflux and fecal incontinence. ,...ers, which are the bands of muscle that separate t...ss in these areas can cause gastrointestinal esoph...
(Date:12/4/2009)...t men can be bastards and women must wear pearls a...nswer, according to an article in the Journal of ...xpressions. , In two studies, researchers asked ... In the first study, androgynous faces with lowere... more likely to be identified as male, and faces w...
(Date:12/4/2009)... federal regulators to crack down on abuse of opio...hDay News) -- The makers of 24 different prescript...tors with plans to curb the abuse of these opioid ...n under pressure from U.S. Food and Drug Administr... of fatal overdoses that occur with these medicati...
(Date:12/4/2009)... back during winter isn,t known, CDC says, , ...ber of states reporting widespread swine flu activ... high of 48 just two weeks ago, a U.S. health offi...N1 swine flu vaccine continues to increase, Dr. Th...Disease Control and Prevention, said during an aft...
(Date:12/4/2009)...lood vessel growth after heart attack , ,...lls appear to help repair heart attack damage, a n...nts found that stem cells from donor bone marrow p...issue damaged by heart attack. , The patients r... having a heart attack. During follow-up, they wer...
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