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Tag: "genetic" at biology news

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...ned on inside cells," said Casey. Ras is a normal genetic component of the cell, but mutations in the gene c...ts showed that knocking out the Icmt protein using genetic targeting also inhibited Ras, so the scientists decided to search for an effective and specific mole...

Tiny scaffolding allows stem cells to become working fat cells

...ey do in normal tissue. They failed to produce the genetic and biologic components that all cells require to do their work. This discovery offers hope of a new approach to growing fat tissue for use in breast reconstruction surgery and other clinical needs, and may even be important for curing type II diabe...

Plants defy Mendel's inheritance laws, may prompt textbook changes

...al traits carried by their grandparents, bypassing genetic abnormalities carried by both parents. These muta...plants apparently have hidden templates containing genetic information from the preceding generation that can be transferred to their offspring, even though th...

New RNA polymerase discovered in plants

...aits. It does its job by copying a template of DNA genetic information in order to make RNAs that encode prot...velopment, but that proved wrong." In a series of genetic and biochemical tests , Pikaard and his collaborators discovered that Pol IV does not share in the d...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...ation and turnover of this layer. In people with a genetic predisposition, like those with Familial Adenomato...radigm for gastrointestinal tumorigenesis, in that genetic events outside the epithelial layer itself have a profound effect on tumor initiation. Thus it appea...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

... especially in patients who don't have the classic genetic mutations that physicians normally use to diagnose the disease. It will also be very interesting to study the effect of drugs that block TEL2 activity, since such an approach might one day represent an effective treatment for leukemia patients." Oth...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...uitfly, fewer than a rice plant—a more fundamental genetic truth has often been obscured. The expression of 20,000?0,000 genes is under the control of an uncounted host of non-coding sequences, which bind transcription factors and thereby regulate when and where genes are expressed. Unlike coding sequences, ...

UCSD team discovers specialized, rare heart stem cells in newborns

... in newborn rats, the UCSD team used sophisticated genetic methods to tag the progenitor cells in living embryonic tissue and in the newborn heart of mice. With these techniques, they were able to show that the isl1+ progenitor cells were spontaneously able to form cardiac muscle tissue. "Furthermore, the c...

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...ealthcare by accelerating the translation of basic genetic research into tools for better diagnosis, prognosi.... During the next five years the projects include genetic analyses and measurement of gene expression in patients with atherosclerosis, breast cancer, rheumat...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...able living cells to change their MRI contrast via genetic instructions." "The new imaging method is a platform technology that can be adapted for many tissue types and for a range of preclinical uses in conjunction with emerging molecular therapeutic strategies," Ahrens said. Ahrens' new approach uses mag...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...lth University researchers have identified several genetic changes in the brains of mice caused by ethanol, w...ted by alcohol that may play a role in determining genetic differences in behavioral responses to alcohol. "These findings help us to better understand the mo...

How an AIDS-Related Cancer Unleashes Inflammation

...nging the stability of cytokine messenger RNA ?the genetic blueprint for cytokine proteins. The longer these messenger RNAs remain in the cell, the more cytokine proteins the cell's protein-making machinery is able to synthesize, said Ganem. The activation of MK2 also increases production of blood-vessel-fo...

Applied Biosystems Introduces Advanced Gene Expression Service Provider Program

...e program, intended to assist service providers in genetic analysis using interpretation tools and content to advance scientific research while helping them achieve necessary return on investment, was announced today in advance of this weekend’s annual World Microarray Congress in Vancouver, Canada. The App...

Sequencing of marine bacterium will help study of cell communication

...t assigns functions to genes. Having access to the genetic sequence in order to perform this chore gave Stevens and Faini early access to specific information about the genes of the bacterium she has been studying for several years. Many different bacteria use quorum sensing. Stevens explains that cells rel...

Harnessing microbes, one by one, to build a better nanoworld

...e program, intended to assist service providers in genetic analysis using interpretation tools and content to advance scientific research while helping them achieve necessary return on investment, was announced today in advance of this weekend’s annual World Microarray Congress in Vancouver, Canada. The App...

Chemists identify key gene in development of type 1 diabetes

...those who have blood markers ?either antibodies or genetic markers ?that are predictive of the disease but are still able to produce insulin. Al-Abed and his associates hope that the experimental compound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achi...

International HapMap consortium expands mapping effort

...plans to create an even more powerful map of human genetic variation than originally envisioned. The map will...for completing its map of common patterns of human genetic variation, also known as haplotypes. By the end of February 2005, however, the group already will ha...

Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth

...The UB researchers currently are examining whether genetic polymorphisms involving PAH metabolism may modify the risk, if lifeline cumulative exposure may be associated with the risk and if this study may be replicated in another geographic settings. Jo Freudenheim, Ph.D., UB professor of social and prevent...

Towards precise classification of cancers based on robust gene functional expression profiles

...those who have blood markers ?either antibodies or genetic markers ?that are predictive of the disease but are still able to produce insulin. Al-Abed and his associates hope that the experimental compound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achi...

Children's taste sensitivity and food choices influenced by taste gene

...sive to bitter taste. Using cheek swabs to obtain genetic samples, researchers classified 143 children and t...perience and culture appear to have overridden the genetic effect." Some mothers and their children may live in different sensory worlds due to differences of...

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