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Tag: "genetic" at biology news

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...o be vital in generating energy, copying thecell's genetic code and protecting the cell from free radicals an... Without messenger RNA, agene cannot translate its genetic code into proteins that carry out itsintended functions.Thiele said the same scenario may occur in h...

Scientists seek answers on what activates deadly anthrax spores

...r Structural Biology will be used to determine how genetic information in the anthrax chromosome translates into a vast array of protein structures, Claiborne said. Once they know the structures, they may not only be able to provide new details on how anthrax develops, but also pick out structural vulnerabil...

Found: Missing sequence of the human Y chromosome

...of a long-term effort tocharacterize the molecular genetic basis for Y-chromosome-linkedphenotypes. Rappold a...ly mapped theGCY locus, which is thought to be the genetic determinant ofsex-related stature differences in humans and is in close proximity tothe Y centromere...

The secret lives of whales

...bi of Stanford University. Palumbi has applied new genetic techniques to penetrate over a million years of wh...DNA from individual whales. He was amazed at their genetic variation ?an indicator of the past size of their population. Piecing together their ancient family ...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...ts, brings us closer to our goal of reconstructing genetic history. We now have the picture on the outside of... stringing together strands of detached DNA into a genetic trail that could solve a crime or exonerate the falsely accused," says Dr. Ensley. This patent is p...

Molecular machine may lead to new drugs to combat human diseases

...form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treat...s then can take over without actually changing the genetic code. The results of the Purdue study are published in the January issue of the journal Nature Stru...

An HIV Protein Plays a Surprising Role in Gene Activation

... each charged with transcribing different types of genetic elements. RNA polymerase II transcribes protein-coding genes. RNA polymerases join with so-called general transcription factors to form a pre-initiation complex (PIC) on the gene's promoter, where it binds to region rich in thymine (T) and adenine (A...

Mouse brain tumors mimic those in human genetic disorder

...developed mouse model of braintumors common in the genetic disorder neurofibromatosis 1 (NF1)successfully mimics the human condition and provides unique insightinto tumor development, diagnosis and treatment, according toresearchers at Washington University School of Medicine in St. Louis.After validating th...

New Clues Add 40,000 Years to Age of Human Species

...esearchers, an age that agrees with estimates from genetic studies for the age of the last, common Homo sapiens ancestor, and reinforcing evidence that most of human history transpired in Africa. The study was funded by the National Science Foundation, the L. S. B. Leakey Foundation, the National Geograph...

Gene variations explain drug dose required to control seizures

...rugs. The findings suggest that, by incorporating genetic tests into the prescription process, physicians mi...t tailoring the treatment of epilepsy to patients' genetic makeup, between the Department of Clinical and Experimental Epilepsy at the University College Londo...

Solution to Pollution: New Bacteria Eats Toxic Waste

...ed Biosystems funded the biologists to examine the genetic material for the five isolates. They answered ques...essor. The Department of Energy will sequence the genetic material of the microbes, and the researchers will then participate in the annotation process by whi...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...phy, they added. Muscular dystrophies include many genetic diseases, all of which are characterized by progressive weakness and degeneration of the skeletal muscles which control movement. The Muscular Dystrophy Association and Genzyme Corporation supported the research. Several forms of Pompe disease affe...

Enzyme shown to help protect genomic stability

... for protection against unwanted recombinations of genetic material or other disruptions of the genome's inte...ranscription and possibly protected from dangerous genetic recombinations with other regions of the genome. A report on the research, which was conducted in ye...

Scientists decipher genome of fungus that can cause life-threatening infections

...ndation for the developmentand implementation of a genetic map for quantitative genetics andpopulation analysis. In addition, the accuracy of the gene annotationmakes it feasible to use Cryptococcus as a model to study how fungicause disease. Using the genomic sequence data, the Cryptococcusresearch communit...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...e expressed in the brains of developing mice.Using genetic probes to investigate thin sections of mouse brains, thescientists found that only 349 of the TF genes were expressed inspecific regions, and not throughout the brain, as the majority were.They inferred that these 349 genes, therefore, controlled the...

U-M scientists find genes that control growth of common skin cancer

...hor on the paper. This is different frommany other genetic mouse models of cancer, in which tumor regressionfollowing inhibition of an oncogene is frequently followed by theemergence of malignancies that have activated alternativecancer-causing pathways. According to Hutchin, the fact that this doesnot happe...

Critical role in programmed cell death identified

...th a well documented cell lineage that facilitates genetic manipulation. Their cell death machinery is simple, with one component for each of the different factors involved in the central cell killing apparatus. Mammals on the other hand have multiple components or families of proteins for these factors; mor...

Genetically modified natural killer immune cells attack, kill leukemia cells

...atient while in remission and then reinfused after genetic modification if the patient suffers a resurgence of the leukemia. "We look forward to seeing this strategy being added to the management of children with ALL," said Chihaya Imai, M.D., the postdoctoral student who did most of the work on this projec...

Nanogen Issued Patent for Electronic Microarray With Memory

...tations associated with cancer, cardiovascular and genetic diseases. The next generation instrument system, the NanoChip(R) 400, is expected to be available in 2005. Nanogen's subsidiary SynX offers a line of point-of-care diagnostic tests and is building expertise in cardiac related health conditions. Nanog...

Researchers find missing genes of ancient organism

...essors of more modern organisms that have gained a genetic load in the process of evolution," said Söll. "Or ... represent a specialization that has rid itself of genetic baggage to exist in extreme environments." Understanding how primitive organisms like Nanoarchaea o...

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