Tag: "genetic" at biology news

Association of herpesvirus with lung disorder questioned

...d to heart failure. Some cases are associated with genetic susceptibility, the investigators noted, but the pathogenesis of most cases is not known. Dr. Katano and colleagues conducted their research using a design similar to that in the earlier study: a retrospective analysis of pathology specimens from a ...

Man and mouse share genome structures

...w microarray technology to identify the underlying genetic sequences associated with the tagged chromatin. Next, they teamed up with Michael Kamal, the co-first author of the paper, Eric Lander, and their Broad Institute colleagues, for the daunting computational analysis required to interpret the resulting ...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...the accumulation of DNA damage and accelerates the genetic changes involved in carcinogenesis. To evaluate whether reduced DNA repair capacity in the nucleotide excision pathway that fixes DNA alterations known as bulky DNA adducts is associated with breast cancer risk, Regina M. Santella, Ph.D., of the Col...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...anGenetics. "These findings are probably the first genetic pieces of ahuge 'interferon puzzle,' with whose he...ith world leaders in thetechnology for large-scale genetic analyses and statistics. The geneticand statistical analyses were performed by the doctoral student ...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

... that photolyases may besuccessfully employed as a genetic tool to combat UV-induced skincancer....

W.M. Keck Foundation funds study of friendly microbes

...ole in helping to devise new ways to translate the genetic data obtained from genome sequencing projects to allow researchers to better understand the evolution and diversity of life on Earth, as well as help create new methods to diagnose and treat patients with common and uncommon diseases. "The CGS repre...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...n, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 pe...hen these mice also carried a colon-cancer-causing genetic mutation, they developed twice as many tumors as those with normal IGF2 levels, the researchers repo...

Fox Chase Cancer Center scientists identify immune-system mutation

...ogist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this natur...

Neuronal 'traffic jam' marks early Alzheimer's disease

...t develop spontaneously in people without an overt genetic defect, as the transport machinery in their neurons breaks down with age. "A person could have a predisposition to the disease, or it could just be that as time progresses, one person could by chance accumulate these blockages more than another," sai...

Timing is everything: First step in protein building revealed

...entists has unraveled the firststep in translating genetic information in order to build a protein,only to fi...of the ribosome'smolecular comings and goings, and genetic studies that create mutantribosome parts, which likely affect ribosome function -- and change itstim...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...n Diego, CA, and Barcelona, Spain, have identified genetic and protein markers that can predict whether a CLL patient will follow the benign or aggressive course. Some markers are not yet available for clinical use, however according to the review, measurement of one protein marker called ZAP-70 is becoming ...

Scientists Replicate Hepatitis C Virus in Laboratory

...?meaning that it contained only nucleic acids, the genetic material of the virus, and did not have the HCV viral envelope, a protective shell of lipids and proteins that surrounds the viral RNA in fully-formed HCV. The naked HCV construct was then placed into human liver cells in a cell culture medium. The ...

Scientists detect probable genetic cause of some Parkinson's disease cases

...n in a recently discovered gene is the most common genetic causeof Parkinson's disease identified to date. Th...se. Thefindings could lead to the development of a genetic test to detect themutation in individuals at risk. The research team includesinvestigators at the Na...

Ecological destruction fuels emerging diseases

...ular taxonomy tools to classify parasites based on genetic characteristics. "These things are evolutionary accidents waiting to happen," he warns. "This is not something brand new ?it's something old. But in this case it's something that human beings are stimulating. These little evolutionary land mines are...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...ses to screen hundreds of specimens forcoronavirus genetic material. Ultimately, two specimens were identifie...nsive care.Analysis of the New Haven coronavirus's genetic structure showed manysimilarities to that of a coronavirus recently identified by two groupsin the N...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...therapyis a promising approach to the treatment of genetic disorders,debilitating neurological diseases such as Parkinson’s and endocrinedisorders such as diabetes. This technology may therefore yieldprofound benefits for human health and quality of life.“The technology developed by Dr. Gao and her collabora...

Whole genome fine map of rice completed

...ue to any one of the two strains. Even though the genetic difference between the two strains is small, there...lysis for the maternal strain "PeiAi 64" (its main genetic background being Japonica, as well as a mixture of Indica and Japonica genes ). This would further h...

Research on Worms Yields Clues on Aging

...trol body movement.Scientists previously had found genetic mutations in C. elegans thataffect both the nervous system and life span. The researchers usedthese mutant worms to further pin down the mechanism by which theanticonvulsants increased longevity.The worms' mutated genes affect the function of sensory...

“Nano-scissors?laser shows precise surgical capability

...ary form, opening the door to other experiments on genetic andmolecular factors that determine whether damaged nerve cells regrow.Ben-Yakar developed the femtosecond laser surgery technique using thelaboratories and equipment of Dr. Robert Byer, a Stanford Universityprofessor, while doing post-doctoral work....

Cytoplasm affects the number of vertebrae in carp-goldfish clones

...hina, conclude that the egg cytoplasm, and not the genetic code of the transplanted nucleus, influenced this aspect of the skeleton as the cloned fish developed. They speculate that a so-called "segmentation clock" early in embryonic development is controlled by the egg cytoplasm. Thus the egg cytoplasm of ...

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