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Tag: "genes" at biology news

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...'s all in the packaging. How nature wraps and tags genes determines if and when they become active, accordi...surprising and previously unknown specifics of how genes get switched on during development of the human body and in diseases such as cancer. "Each type of ...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...ch genes?called “transcription factors.?When these genes are altered, thegenes they control can go awry, ca...of the major brain areasthat shows what regulatory genes are expressed in those specificlocations,?said Quifu Ma, PhD, of Dana-Farber’s Cancer BiologyDepartm...

U-M scientists find genes that control growth of common skin cancer

...r and the National Cancer Institute haveidentified genes that promote the growth and recurrence of skin cancer.Andrzej Dlugosz, M.D., a professor of dermatology in the U-M MedicalSchool, and colleagues at the University of Michigan and the NationalCancer Institute examined the functions of the Hedgehog (Hh...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

..." view of the human genome, there are about 26,000 genes used to make proteins that ultimately control the structure and function of every cell in the body. Most disease research has focused on studying these protein-coding genes, even though they make up only about two percent of the human genome sequence...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...Research Triangle Park, N.C., have deleted certain genes from theVEE virus, thereby making it impossible fo...the HER2/neu protein in place of the deleted viral genes and thenpackaged the virus vector into virus-like replicon particles, referredto as “VRP-neu.?When t...

Highly adaptable genome in gut bacterium key to intestinal health

...n gut adaptively shifts more than a quarter of its genes into high gear when its host's diet changes from s...simple sugars. Ten days later, the activity of all genes in the bacterial genome was surveyed in B. theta from the mice's guts. The research team found that...

Researchers find missing genes of ancient organism

...ts report in the journal Nature that the "missing" genes for tRNA in an ancient parasite are made up by spl...mewhat similar to internal sequences found in tRNA genes of more complex organisms., These regions, termed introns, are sequences that are cut out of whole g...

Scientists identify genetic pathways essential to RNA interference

...setts General Hospital (MGH) has identified 80 new genes essential to the process of RNA interference (RNAi), a powerful new research tool for inactivating genes in plants or animals. They used the RNAi process itself to find new genes that participate in the ge...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...Research Triangle Park, N.C., have deleted certain genes from theVEE virus, thereby making it impossible fo...the HER2/neu protein in place of the deleted viral genes and thenpackaged the virus vector into virus-like replicon particles, referredto as “VRP-neu.?When t...

Ants Genetic Engineering Leads To Species Interdependency

...anevolutionary innovation involving the sharing of genes between two antspecies has given rise to a deep-se...e workersare hybrids that possess a combination of genes from the two species ina single individual.It is not currently known whether the ants benefit from h...

Same mutation aided evolution in many fish species, Stanford study finds

...redict we would find mutations in any of the three genes in sticklebacks," said Kingsley, who is also a How...am near Fresno. Perhaps mutations in the two other genes cause problems for the fish in addition to reducing the number of armor plates, Kingsley said. Most...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...ing the genetic coding problem, the problem of how genes controlled the synthesis of proteins. In 1961, he ... turned to developmental biology, the study of how genes control the growth and specialization of organs. In 1976, Crick moved to the Salk Institute for Bio...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...ease in its later stages. By inserting corrective genes into the brain, scientists studying small monkeys called marmosets prevented brain damage by producing therapeutic levels of a protein that helps nourish brain cells, said Ron Mandel, Ph.D., a scientist with the University of Florida's McKnight Brain...

Researchers trace evolution to relatively simple genetic changes

...ine. "People have been interested in whether a few genes are involved, or whether changes in many different genes are required to produce major changes in wild populations." The answer, based on new research, is t...

Scientists reveal molecular secrets of the malaria parasite

...le is helping researchersunderstand when different genes switch on and off as the pathogensmetamorphose thr...'s findings will help scientists identify parasite genes that areinteracting with the host as well as new gene targets for vaccines thataim to prevent parasi...

Octopuses occasionally stroll around on two arms, UC Berkeley biologists report

...ine. "People have been interested in whether a few genes are involved, or whether changes in many different genes are required to produce major changes in wild populations." The answer, based on new research, is t...

Studies reveal methods viruses use to sidestep immune system

...latory factor 3 (IRF-3). This protein turns on the genes responsible for producing interferon, which neutra...-3. Without those signals, IRF-3 can't turn on the genes to make interferon, and the virus continues to replicate unimpeded. "Having identified RIG-I, now w...

Alcohol's effects on gene expression in the central nervous system

...s can appear and work so differently with the same genes ?giving us, for example, unique eyes, skin, or hair ?is that only some genes are used or 'turned on' in each cell. This is called gene expression." McBride said that researcher...

An entropy-based gene selection method for cancer classification using microarray data

...h; yet the selection of non-redundant but relevant genes is difficult. The selected gene set should be smal...regular clinical laboratories and ideally identify genes involved in cancer-specific regulatory pathways. Here an entropy-based method is proposed that selec...

Jumping gene helps explain immune system's abilities

...nt proteins might have originated from a family of genes whoseonly apparent function is to jump around in g...nation."Understanding how Hermes and other jumping genes work also holds cluesto fighting bacterial infections, improving gene therapies and tacklingdisease-...

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