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Tag: "genes" at biology news

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...enome have been annotated as antibiotic resistance genes due to their sequence similarity to existing antib...en reading frame is compared with the sequences of genes for other proteins (most of which are from different species) in sequence databases. If a close matc...

Novel Enzyme Shows Potential As An Anti-HIV Target

...e virus is integrated (now called a provirus), its genes can be transcribed. Adept as HIV is in exploiting...scription by modifying Tat. The regulation of HIV genes depends on a complex interplay between proviral DNA, cellular proteins and transcription factors, an...

Found: Missing sequence of the human Y chromosome

...ome. This sequencecontains eight putatively active genes that could be implicated insex-associated height d... active genes, further functional testing of these genes mayreveal insights into the genetic basis for stature and gonadoblastoma....

Study finds more than one-third of human genome regulated by RNA

...llular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this t...es. In December 2003, the samegroup identified 400 genes in the human genome targeted by microRNAs.(Prior to this study, there were no known microRNA targets...

The secret lives of whales

...nged.?/p> Palumbi compares the ability to read genes to counting the rings of a tree ?but looking at the history of an entire population, not just an individual. “Knowing the history of populations is critically important to managing their future,?says Palumbi, “especially for populations like these wh...

NYU researchers simulate molecular biological clock

...llular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this t...es. In December 2003, the samegroup identified 400 genes in the human genome targeted by microRNAs.(Prior to this study, there were no known microRNA targets...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...t covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scien...eces of aged DNA, we should be able to reconstruct genes from animals such as the wooly mammoth, giant sloth, saber-toothed cat or even from tissues of the T...

Gene therapy converts dead bone graft to new, living tissue

...re robust, Schwarz looked into the activity of the genes and proteins that govern its health. His team repl...levels of the active genes. He discovered that the genes that create two key proteins in living bone, called RANKL and VEGF, were barely expressed around the...

Molecular machine may lead to new drugs to combat human diseases

...olden, associate professor of biochemistry. Normal genes then can take over without actually changing the genetic code. The results of the Purdue study are published in the January issue of the journal Nature Structural and Molecular Biology. "In terms of human health, Group I introns are interesting be...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...E toxicity atthe single-neuron level to learn what genes are turned on and off bythe exposure to the chemical mixture. The research is focused on afamily of genes known as P53, which helps to regulate the cell cycle.They have also moved their studies to a new mod...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...E toxicity atthe single-neuron level to learn what genes are turned on and off bythe exposure to the chemical mixture. The research is focused on afamily of genes known as P53, which helps to regulate the cell cycle.They have also moved their studies to a new mod...

Automatic extraction of gene/protein biological functions from biomedical text

...ritical. Since automatic functional annotations of genes are quite useful for interpreting large amounts of high-throughput data efficiently, the demand for automatic extraction of information related to gene functions from text has been increasing. Results: We have developed a method for automatically ex...

A bacterial genome reveals new targets to combat infectious disease

...illion base pairs, and many metabolically critical genes have degraded through mutation to the point of uselessness. This phenomenon, called reductive evolution, is typical of long-term symbioses, as the two partners increasingly complement one another's biochemical activities. Slatko and colleagues enume...

Gene variations explain drug dose required to control seizures

Determining which variants of particular genes patients with epilepsy carry might enable doctors ... them. The researchers found that variants of two genes were more likely to be found in patients who required higher dosages of anti-epileptic drugs. The f...

Solution to Pollution: New Bacteria Eats Toxic Waste

...hen participate in the annotation process by which genes in the sequences will be identified. The researchers will be able to understand the genetic material that allows these bacteria to degrade the PAHs and survive in the soil. Such knowledge may help researchers better understand and utilize the organis...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...s also said their approach of targeting corrective genes to muscles may have application in treating other ...tudy. "By restricting the expression of introduced genes to muscle, the immune response can be prevented or attenuated." The muscle-targeted gene therapy mi...

Enzyme shown to help protect genomic stability

...tive, lengthy stretches of DNA containing multiple genes that are closed to gene transcription. Scientists ...he DNA is tightly wrapped around the histones, the genes cannot be accessed and their expression is repressed. When the coils of DNA around the histones are ...

BRCA1 causes ovarian cancer through indirect, biochemical route

Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering wi...lopian tubes, and that the mice with mutated BRCA1 genes in their granulosa cells developed tumors there as well. "This not only underscores the relevance of...

Scientists decipher genome of fungus that can cause life-threatening infections

...s. TheScience study identified greater than 30 new genes likely involved incapsule biosynthesis, including ... factors than the absence orpresence of individual genes in the two isolates. A combination ofother factors ?perhaps including the cumulative impact of small...

Needling Chromosomes Reveals Cell Division Secret

... DNA strands on each chromatid. DNA, whichmakes up genes in the cell, replicates itself as a central process inchromosome duplication."So, we’re left with the mystery of what molecules hold the chromatidstogether at this point in cell division,?Nicklas said. "But that’s theusual outcome of work in my labor...

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