generated 2 1

Tag: "generated" at biology news

Wisconsin scientists grow critical nerve cells

...m and precise timing. To start, the Wisconsin team generated neural stem cells from the embryonic stem cells. T...ab dish into spinal motor neuron cells. The newly generated motor neurons, according to Zhang, exhibit telltale electrical activity, a sign that the neurons, wh...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...th in New York, and colleagues analyzed cell lines generated from blood samples taken from pairs of sisters in which one sister had been diagnosed with breast cancer and the other had not. They found that DNA repair capacity was lower in breast cancer patients than in the control subjects. Deficient DNA repai...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

... shown thatdopamine-producing neurons (DA neurons) generated from monkey embryonicstem cells and transplanted i...eircurrent JCI study, Jun Takahashi and colleagues generated neurons frommonkey embryonic stem cells and exposed these cells to FGF20, a growthfactor that is pro...

The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life

...presentation of SPIM at scientific conferences has generated a flood of requests for the instrument. "We were extremely pleased to have found Carl Zeiss as an excellent partner to translate this technology into a product," says Dr. Martin Raditsch, Deputy Managing Director of EMBLEM. EMBL Director-General Pr...

Mitochondrial DNA mutations play significant role in prostate cancer

...dical production. The tumors withthe mutant mtDNAs generated significantly more oxygen radicals thanthose with normal ntDNAs, suggesting that this may be an importantcontributory factor in the mitochondrial enhancement of prostate cancertumor growth. Because the study found that COI mutations were common inthe...

Highly adaptable genome in gut bacterium key to intestinal health

...cies. The complete genome sequence of B. theta was generated two years ago in the same laboratory. The researchers inoculated germ-free mice, who have no intestinal bacteria, with B. theta. The mice were fed a diet high in complex carbohydrates and low in simple sugars. Ten days later, the activity of all gen...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...m has found that 90 to 95 percent of light scatter generated is from optical properties of mitochondria. Working with UCSD According to Bob Naviaux, professor at the School of Medicine at the University of California at San Diego and co-director of its Mitochondrial and Metabolic Disease Center, "What's attr...

Scientists identify new model Of NK cell development

...ts have believed for years that human NK cells are generated in bone marrow, but Michael Caligiuri, director of the OSU Comprehensive Cancer Center and the senior author of the study, says research in his laboratory shows that the precursors to NK cells are actually found in cellular nurseries deep inside the ...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

...rmaceuticals industry, a fast-growing sector which generated US$143 billion sales in 2003. Other applications of IBN’s nanoporous nanoparticles involve therapeutic treatments like targeted drug delivery and gene therapy. Nanoparticles of varying size and structure may be created to act as carriers for drugs, ...

RNA project to create language for scientists worldwide

... Leontis said. The possible applications of newly generated knowledge about RNA are vast. RNA science already is playing an important role in understanding normal and abnormal metabolism and physiology and in designing new strategies for intervention in the form of gene therapy, Leontis said. ...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...th 38,965 known interactions. Their PathBLAST tool generated a list of similar proteins in the three species th...sting proteins. Such novel arrangements would have generated new capabilities or changed existing ones. Pharmaceutical companies have also not had the luxury of...

Wisconsin researchers identify sleep gene

...sium channels. And we know that slow waves must be generated by changes in the excitability of neuron cell membranes," Cirelli says. "Potassium changes may have a huge affect on sleep in humans." Sleep is a highly complex activity and probably involves many genes, some of which are more influential than othe...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...ood. The first human clone of this channel, K2P1, generated a good deal of excitement, Goldstein said, but no one could learn much about it because it always seemed to be mute. "This discouraged a lot of people." The problem was that some hidden mechanism was silencing the channel, plugging the pipeline, but...

Researchers rein in regulatory RNAs

...e transcripts, or SATs, are pairs of RNA molecules generated from opposite DNA strands at the same locus. The n...ndomly chosen SAT pairs revealed that the SAT loci generated multiple transcripts of various sizes, in contrast to a single transcript that is expected under the...

Microbial fuel cell: High yield hydrogen source and wastewater cleaner

... much hydrogen directly out of biomass than can be generated typically by fermentation alone. Dr. Bruce Logan, the Kappe professor of environmental engineering and an inventor of the MFC, says, "This MFC process is not limited to using only carbohydrate-based biomass for hydrogen production like conventional ...

Strongest proof yet found for prion hypothesis

...the only remaining prions were those that had been generated in the test tubes. These were then injected into the brains of healthy hamsters, which began showing TSE symptoms within four months and, on average, died less than six months after inoculation. "For many years, people have tried to make these infec...

Yeast Network Prevents Damage By Oxygen Radicals

...OS." Dr. Kolodner and lead author, Meng-Er Huang, generated various yeast strains each with a mutation in the TSA1 gene, which results in increased production of ROS, plus a mutation in one or more genes involved in DNA repair or cell cycle control. Cell survival and accumulation of DNA mutations and gross ch...

CoPub Mapper: mining MEDLINE based on search term co-publication

...ngs for 15,621 known genes and 3,731 keywords were generated and validated. PubMed IDs were retrieved from MEDLINE and relative probability of co-occurrences of all gene-gene and gene-keyword pairs determined. To assess gene clustering according to literature co-publication, 150 genes consisting of 8 sets with...

Different microarray systems more alike than previously thought

...y provides new hope that the mounds of information generated by these systems might actually be comparable, eve... In general, the study showed Affymetrix GeneChips generated more reproducible data than the other microarrays. But the researchers also showed that any of the ...

Study: 'homemade' gene expression technology unreliable

...sed by seven consortium laboratories, all of which generated data from two standard RNA expression samples, one derived from mouse livers and the other taken from tissues of several mouse organs. According to the study, reproducibility between platforms and across laboratories was generally poor, but reproduc...

1 2 3 4 5 6 7 8 9 10