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Tag: "fused" at biology news

Plants defy Mendel's inheritance laws, may prompt textbook changes

... plants. In the deformed parents, the flowers were fused into tight balls. But in the grandparents and 10 percent of the grandchildren, the buds become 1-millimeter-long, bright white flowers that fully opened and radiated out from the center of a cluster. "If you take this mutant Arabidopsis, which has t...

Revolutionary nanotechnology illuminates brain cells at work

... amino acids. A protein of interest is genetically fused with two differently colored tags made from variants of the jellyfish Green Fluorescent Protein (GFP). The colored tags are placed at each end of the molecule making a "biosensor." When the substance of interest binds to the sensor, the sensor backbo...

NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells

... the cell membrane, when the vesicles combined, or fused with, the membrane. Researchers had been unable to determine, however, where in the cell the vesicles were stored and how insulin stimulated them to fuse with the cell membrane. In the current study, the NIH researchers observed fat cells taken from...

Double triumph in stem cell quest

...d ESC will reprogram the donor nuclei, turning the fused cell into an ESC too. The result, Verlinsky told a...the adult donors? Verlinsky's response was that he fused male adult cells with a female ESC line, and the resulting cells were male. However, Verlinsky's tea...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...ansferrin, a plasma protein found in blood, can be fused with large, protein-based drugs such as granulocyte colony-stimulating factor (G-CSF) to create a new oral compound that is capable of surviving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloodstream to b...

Breakthrough: Scientists create world's tiniest organic particles

...splay technologies."Prior to this, no one else has fused the highly uniform and precise methods for fabricating transistors with the organic nanoparticle world," said Bruce Boucher, president of Liquidia. "It is truly a revolutionary discovery." ...

Researchers devise new technique for creating human stem cells

...programming can occur when mouse somatic cells are fused to mouse embryonic stem cells. The scientists knew...eved fusion of the two cell types by searching the fused cells for two distinctive genetic markers present in the somatic fibroblast and stem cells. The rese...

A molecule impedes the destruction of the 'Brucella' bacteria

...acrophages within membranous vesicles that are not fused with lysosomes (structures containing cellular products necessary to destroy bacteria) as occurs in other micro-organisms. On the contrary, they reach certain compartments within the macrophage. Here the bacteria multiply and establish a chain of eve...

Scientists devise way to measure RNA synthesis on the fly in a live cell

... to a protein called MS2. This MS2 protein also is fused to a green fluorescent protein that a laser can de...ally small volume. In the absence of RNA, the MS2 fused to the fluorescent protein moves rapidly. But when bound to RNA, the fused proteins move more slowly...

Malfunctioning bone marrow cells sabotage nerve cells in diabetes

...ound that, in diabetes, only nerve cells that have fused with bone marrow cells display the abnormal function and premature death found in neuropathy. Nerve cells that have not merged with the insulin-producing bone marrow cells remain intact and function normally. "Based on these findings, we speculate t...

UCR biochemist goes to Washington with high-protein corn

... aborted flower, resulting in two kernels that are fused together. "Despite the fusion, the kernels are not bigger," Gallie said. "It's basically the same corn, except that it is protein-rich and starch-poor - something that, if applied to sweet corn, would appeal to a large number of weight-conscious peop...

Firefly protein lets researchers monitor molecule linked to cancer

...r cells and by using a technique that inserted the fused IKB/luciferase protein into liver cells only. They are currently working to develop a line of mice with the IKB/luciferase fusion built into its genetic code. In addition, they showed that the system is not only helpful for learning if a drug is hav...

Normal chromosome ends elicit a limited DNA damage response

...complement of chromosomes would inevitably rip the fused chromosomes apart. "Such fusion breakage cycles scramble the genome over time, and cause genome instability, which is a hallmark of cancer cells," explains Karlseder. "This demonstrates the importance of telomeres in preserving genome integrity and...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...to feed them. To counteract that, researchers have fused a nanoshell to an antibody; the idea behindsuch "immunonanoshells" is to have a targeted nanoshell that can find a specific type of cancer wherever it may hide, says study author, bioengineering graduate student Amanda Lowery In the study that Lowe...

SLU researchers uncover direct evidence on how HIV invades healthy cells

.... Once inside the cell, the two viral DNA ends are fused by the integrase to the cell's chromosome. The integrated viral DNA allows virus replication. If the two ends of the viral DNA do not come together, infection does not take place. Millions of HIV tainted cells can be launched from a single infected c...

Common viruses may cause cancer

...l infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless be...fortuitously, that normal cultured human cells are fused by the action of the Mason-Pfizer Monkey Virus (MPMV), but that the resulting hybrid cells do indeed...

New evidence supports century-old theory of cancer spread

...as astonishing," said Pawelek. "In culture dishes, fused cells were extraordinarily motile compared to unfused melanoma cells. They spread rapidly when implanted in mice. Even though the idea is virtually unknown to cancer researchers today, many scientists worked on it in the 20th century. From the late 1...

Sea coral's trick helps scientists tag proteins

... tag labeled and tracked target proteins, the team fused Dendra to proteins that form the cytoskeleton of the cell, including actin and tubulin filaments and found the expected patterns of intracellular protein distribution. Dendra belongs to a small family of green-to-red PAFPs. The first protein in thi...

Molecule by molecule, new assay shows real-time gene activity

...e inclusion of the Tsr domain serves to anchor the fused protein to a cell's membrane, sidestepping the longstanding difficulty of imaging single proteins zipping about in cell cytoplasm, where diffuse fluorescent signals tend to be overwhelmed by background noise. The gene coding for this combined protei...

FSU biologist says new dinosaur is oldest cousin of Tyrannosaurus rex

...haracteristic long hip, the U-shaped teeth and the fused nasal bridge. While they weren't exactly T. rex look-alikes, they were definitely family. But there were marked differences. Among them, in addition to its distinctive cranial crest, Guanlong was roughly 100 million years older and a fourth the size...

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