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Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...uture computer simulations of HIV dynamics to help further drug discovery and prevent deadly infections. “We found that HIV fusion peptide dramatically decreases the amount of energy needed to bend a cell-like membrane,” said Stephanie Tristram-Nagle, associate research professor of biological physics at Ca...

Common cancer gene sends death order to tiny killer

...d p53, but fewer were killed in cells lacking p53, further suggesting that this microRNA gets its kill orders from p53. When researchers examined pancreatic cancer cells known to contain damaged or missing p53, they found that those cells had limited or zero miR-34a. "With no p53 gene or miR-34a to st...

Blood test may help signal tumor's remission, return in throat cancer patients

...not to throat cancer; therefore, they caution that further studies are needed in larger groups of patients to confirm if this could be a useful tool to monitor for cancer, infection, or other complications. In addition, because IL-6, IL-8, VEGF, and HGF have been detected in the blood of patients with breast...

Pregnant mom's exposure to flu vaccine kick-starts fetal immune system

...f cord blood specimens examined. These results and further data reported in the study establish that B and T cell responses to antigens occur in utero following maternal vaccination against influenza, supporting the theory that the human neonatal immune system is not deficient or incompetent but, rather, cap...

CSIRO scientists join fight to save 'Tassie devil'

...ed animals and have also collected and processed a further 30 affected animals where both tumour tissue and tumours grown in the laboratory were examined. A recent Senior Scientist’s Scientific Forum on the DFTD reviewed progress in understanding and managing the disease and set an agenda for future rese...

Dirty snow may warm Arctic as much as greenhouse gases

... century, so cutting back on emissions can prevent further warming but does not produce immediate cooling....

New bacterium discovered -- related to cause of trench fever

... to different drugs, so it is essential to explore further and pinpoint which one is involved.” The cat scratch bacteria and the one that brought down soldiers and AIDS patients can be reined in with the same antibiotic, but the Peruvian microbe is usually countered with different antibiotics, Koehler sa...

Columbine flowers develop long nectar spurs in response to pollinators

...ors occurs very rapidly, followed by periods of no further evolution until another pollinator shift occurs, according to William Zamer, deputy director of NSF's division of integrative organismal systems. "In the case of these flowers, changes appear to happen relatively rapidly in response to changes in ...

Ancient DNA traces the woolly mammoth's disappearance

...ore merging back into a single population. The DNA further suggests that no later than forty thousand years ago, one of the groups died out, leaving only the second alive at the time of the mammoth’s last gasp. “At a time when we should be very concerned about the potential extinction of many existing lar...

New study finds genetically engineered crops could play a role in sustainable agriculture

...e reductions of certain animal groups that warrant further investigation.” What is clear is that the advantages or disadvantages of GM crops depend on the specific goals and vision for agroecosystems. As NCEAS Director, Jim Reichman explains, “This important study by an interdisciplinary research team r...

New collaborative research reveals chimpanzees can sustain multiple-tradition cultures

...y researchers believe exist in the wild, providing further evidence chimpanzees and humans shared a common ancestor five to six million years ago who had a similar level of cultural complexity. For years, primatologists have suggested different communities of chimpanzees across Africa vary in many behavio...

'Lucky 13' as new gene discovery offers further hope for childhood blindness

...tosa Society. "This dramatic discovery provides further information enabling us to combat blindness within the Retinitis Pigmentosa group," says Professor Marshall. "The more genes we discover the better we are placed to treat the diseases by methods such as that recently announced at Moorfields Eye Hospi...

Researchers shed light on shrinking of chromosomes

...ing the late shortening of chromosomes. This could further advance our understanding of cell division and the risk factors that lead to defects in chromosome separation and their dramatic consequences....

Now, self-healing materials can mimic human skin, healing again and again

...is repeated. “Ultimately, the ability to achieve further healing events is controlled by the availability of active catalyst,” said Kathleen S. Toohey, a U. of I. graduate student and lead author of the paper. “While we can pump more healing agent into the network, ‘scar tissue’ builds up in the coating an...

Newly discovered antibody may be body's natural defense against Alzheimer's

...generation of disease-modifying treatments. To further confirm that these natural antibodies bind with ol...f the effect of IVIG therapy to clinical outcomes, further investigation in larger controlled and longer-term trials will be needed to definitively demonstrate...

Physicist cracks women's random but always lucky choice of X chromosome

...ng down X chromosome XIST genes in a manner giving further confirmation to Dr Nicodemi’s research. So the randomness is explained but what about researchers’ other concerns" Dr Nicodemi believes the randomness actually does give an evolutionary advantage. The mechanism means equal numbers of both the materna...

Australian wins prestigious prize in biodiversity informatics

...y and natural resource management agencies, and in further developing its contribution to biodiversity conservation planning.”...

Genetic factors are linked to fever following smallpox vaccination

...re acceptable in the future by discovering ways to further reduce the chance of minor adverse events.” I...ions in host responses to vaccines, and notes that further studies will need to replicate these findings, and to test other vaccines. Both Drs. Stanley and Cr...

Penn researchers link cell's protein recycling systems

...ing old, damaged proteins. The researchers suggest further that when proteasomes are impaired or overwhelmed, which leads to accumulation of defective proteins, HDAC6 facilitates delivery to the autophagy-lysosomal system for degradation. “That’s how we think HDAC6 links the two systems,” says Taylor. Dr ...

In nature, proteins sweep up nanoparticles

...the characteristic signal of proteins. Next, to further zero in on this intriguing signal, they examined the sample using an extremely high-spatial-resolution imaging tool called secondary ion probe spectrometry, which is located at the Department of Energy’s Lawrence Livermore National Laboratory. Also c...

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