Study details hepatitis C ability to block immune system response
...se antiviral effects." The knowledge gained from fundamental studies such as these could lay the groundwork for the development of potential new treatment strategies for this devastating global disease. ...Light guides flight of migratory birds
... over the last 30 years have failed to resolve the fundamental question of how migratory birds integrate multiple sources of directional information into a coherent navigational system. Last autumn, Rachel Muheim, a postdoctoral associate in biology professor John Phillips' lab at Virginia Tech, captured Savan...Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein
...reases with age, and a better understanding of the fundamental mechanisms involved in repairing wounds may lead to improved strategies for fostering proper healing with minimal scarring." K17's role in maintaining hair follicle strength is probably centered on its capacity to control the timing of follicle cell...Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
...s from the University of Wisconsin-Madison. This fundamental research about a key step in RNA synthesis has important implications for the study of gene expression in other organisms, and adds to the wealth of knowledge about E. coli contributed by scientists from the UW-Madison. "The kinds of processes that ...When it comes to gene transcription, random pauses aren’t quite so random, study finds
...nthesis. Despite its crucial role in cell biology, fundamental questions remain about how the RNAP enzyme actuall...e control of gene transcription is one of the most fundamental ways to regulate gene expression in general, and one way to control transcription is to control paus...HIV-1's high virulence might be an accident of evolution
...Nef-mediated suppression of T cell activation is a fundamental property of primate lentiviruses that likely evolved to maintain viral persistence in the context of an intact host immune system," the researchers said. "The findings suggest that the gene function was lost during viral evolution in a lineage that g...Scientists identify gene involved in stem cell self-renewal in planaria
...e work could lead to a better understanding of the fundamental mechanisms by which stem cells are regulated; such basic understanding is required for the successful therapeutic application of stem cells in humans. "One of the defining characteristics of stem cells is their ability to self-renew ?that is, to mak...Research links protein to breast-cancer migration
...ch more problematic. "Our research is potentially fundamental to all types of cancers and has the potential to offer alternative therapies to stop cancers spreading to other organs in the body." News of the scientific breakthrough comes as the University announced Breast Cancer Campaign funding for two other r...Study shows frogs can play key role in stem cell research
...o become any of the 200 cell types in the body, is fundamental to all research in the discipline. Until now, stem cells have been obtained from mice, primates and humans, but never from amphibians. But, because the African clawed frog is easier to study than mice and humans, the Edinburgh team anticipate that i...UCSD researchers develop 'smart petri dish'
... of the paper: "The potential of our technique for fundamental studies of cell toxicity is exciting, Since we can monitor cells in real time without removing them from their natural environment, the observed changes provide a time course for performing more detailed tests to find out why drugs are toxic." The s...Gut microbes' partnership helps body extract energy from food, store it as fat
...says. "This project should help answer a number of fundamental questions, including: How different are our individual gut microbiomes? How are our gut microbiomes evolving as a function of changes in our diet, lifestyle and environment? And can we use this knowledge to improve our personal health, including, for...The molecular post office inside the cell
...rted (Science, May 5, 2006). Sorting proteins is fundamental to the gene expression of every organism - from bacteria to humans. Particularly important during biosynthesis is sorting secretory and membrane proteins, which have to find the way to their final destination inside or outside the cell. Secretory pro...Methane-belching bugs inspire a new theory of the origin of life on Earth
...-their discovery also became the inspiration for a fundamental new theory of the origin of life on Earth, reconciling a long-contentious pair of prevailing theories. This new, "thermodynamic" theory of evolution improves upon both previous theories by proposing a central role for energy conservation during earl...In drug design, a loose fit may be best bet
...However this research provides information that is fundamental to cellular signaling, a function that is essential to all cells in all systems in the body, including our sensory systems of hearing, balance, taste, and smell." By tweaking portions of the TRH molecule, the researchers developed six slightly edite......different from vision and audition in lacking this fundamental property," notes senior author Alan Gelperin, PhD, a computational neuroscientist. "We now can use accumulated information about these other sensory systems to help us understand olfaction." Exactly how the many thousands of different odorants are...Mice learn tasks that may help treat human psychiatric disorders
...said. "Previously we were not able to measure this fundamental disease process in autism, trichotillomania (hair pulling), obsessive-compulsive disorder, Parkinson's disease, schizophrenia, Tourette's syndrome, traumatic frontal brain lobe injury and a host of other human mental disorders for which set shifting ...Drug dials down the energy within cells, UM researchers find
...think the way the cells make and utilize energy is fundamental to the disease process. Combining that knowledge with our new knowledge of how to regulate the energy of the cell could open up new avenues for treating disease and monitoring the effectiveness of treatment." ...Medium is the message for stem cells in search of identities
...ain Institute have begun to answer one of the most fundamental questions in science - how does a batch of immatur...sify to form various neural structures, one of the fundamental mysteries of brain development, the researchers say. Since the 1980s, Steindler has studied the ......ain Institute have begun to answer one of the most fundamental questions in science - how does a batch of immatur...sify to form various neural structures, one of the fundamental mysteries of brain development, the researchers say. Since the 1980s, Steindler has studied the ......s the next breeder. The wasps in this queue face a fundamental trade-off: by working harder, they help the group as a whole and as a result indirectly benefit themselves, but they simultaneously decrease their own future survival and fecundity because helping is costly. It involves energy-expensive flight to for...